-
Steroid Regulatory Function at Different Professional Law-Enforcement Officer Groups in Dependence from Professional Load
Roman Victorovich Koubassov,
Yury Evlampievich Barachevsky,
Valery Valentinovich Lupachev,
Elena Nikolaevna Sibileva
Issue:
Volume 1, Issue 3, November 2013
Pages:
44-47
Received:
27 October 2013
Published:
20 November 2013
Abstract: At the present time occur a lot of political, ideological, religion, economic crises and other conflicts that lead to global changes of social sphere. The frequent cases of local armed conflict, terrorism act takes a considerable mobilization of economic and human resources. As a rule, the professional members of a police task force occupation for maintain securities are with extreme environments. The occupational hazard effect may evident by overstrain and depletion of functional regulatory mechanisms that provide the adaptation. The law-enforcement officers of Ministry of Home Affairs, aged 23-35 years were investigated. In according to professional occupation this one was divided in three groups: combatants that send on a mission to Caucasus for maintenance of law order; law-enforcement school students; policemen that maintain law order in territory without war conflict and never take part in combat mission. The blood serum steroid hormones (cortisol, testosterone, progesterone and estradiol) were determined. It was provided comparative analysis of means between groups: combatants before – after mission; combatant – students – policemen. Analyses of our results are shown that hormonal levels at all persons were in normal physiological limits. Together with it, significant differences of steroid serum hormonal means between comparative groups as for dependent samples well as for independent samples were revealed. The differences of endocrine system index (hormonal levels of steroid hormones) at different law-enforcement officer groups with intensive professional stress are reactions for adaptation of organism to extreme factors, probably. They provide optimal adaptive changes to response on environment stress.
Abstract: At the present time occur a lot of political, ideological, religion, economic crises and other conflicts that lead to global changes of social sphere. The frequent cases of local armed conflict, terrorism act takes a considerable mobilization of economic and human resources. As a rule, the professional members of a police task force occupation for ...
Show More
-
About Surgical Tactics in Damages of the Thoracic and Lumbar Parts of the Spine
Issue:
Volume 1, Issue 3, November 2013
Pages:
48-52
Received:
4 November 2013
Published:
30 November 2013
Abstract: In the overall structure of spinal injuries in adults vertebro-spinal injury ranges from 2.2% to 20.6%. When fractures of the spine are complicated by neurological disorders, most commonly lower thoracic and lumbar vertebrae - 39.2% and 48.5% are injured respectively. 45 patients with damage to the thoracic and lumbar spine, admitted to the neurosurgical department of RCSUMA. The main method of preparation of the combined graft is performed in the following manner: Bone graft is taken from the iliac crest and wings of the fibula of the patient, depending on the size of the vertebra. Next, the graft is cleaned of soft tissues and placed in a glass, which contains 3% of hydrogen peroxide, then in a second glass with a solution of broad-spectrum antibiotic for 5-10 minutes. To improve and strengthen support ability of bone graft, a hole is formed in the middle of the graft with the drill, which is then filled with bone cement. Bone cement is dissolved before use with a special solvent and liquid form is introduced with a syringe through the hole formed in the bone graft. The bone cement hardens within the bone hole and thereby enhances support ability of the transplant. To increase the coupling properties of the graft a few teeth are formed at its ends. The resulting clinical and neurological findings in these patients showed that after a comprehensive operative and conservative treatment 31 (68.9%) patients had positive neurological symptoms, increased sensitivity below the level of damage, and also the growth of the movement in the distal extremities was noted improvement of function of the pelvic organs in the form of urination. But despite undertaken complex therapeutic measures in 14 (31.1%) patients is not a marked improvement in neurological performance was not noted during treatment. The dynamics of neurological disorders after surgical treatment showed that in complicated injuries of the body of thoracic and lumbar vertebrae combined graft provides sufficient support ability of the spine and thus creates the conditions necessary to restore the function of damaged spinal cord and its elements
Abstract: In the overall structure of spinal injuries in adults vertebro-spinal injury ranges from 2.2% to 20.6%. When fractures of the spine are complicated by neurological disorders, most commonly lower thoracic and lumbar vertebrae - 39.2% and 48.5% are injured respectively. 45 patients with damage to the thoracic and lumbar spine, admitted to the neurosu...
Show More
-
Asymmetric Redox Status and Cardiovascular Risk Factors in Smoker Women and Men
Laura Celano,
Anabel Vidal,
Alicia Olascoaga,
Walter Alallon,
Ana Denicola,
Leonor Thomson
Issue:
Volume 1, Issue 3, November 2013
Pages:
53-57
Received:
11 December 2013
Published:
30 December 2013
Abstract: Profuse epidemiological evidence supports a higher risk for coronary heart disease and stroke in smoker women than in men with the same habit. Although it is already known that cigarette smoking alters the redox state, is unknown if the imbalance in the normal equilibrium between oxidants and antioxidants is responsible for the elevated female susceptibility. Therefore, the aim of this work was to estimate the effect of smoking on serum redox status in women compared with men, accounting for divergences in other major risk factors for cardiovascular disease. Lipid profile, antioxidant capacity, and serum carbonyls were assessed in 116 healthy Uruguayans, composed by 50 females and 66 males. The smoking habit was declared by 17 females (34 %) and 36 males (54 %). The lipid profile was modified by cigarette smoking, affecting in a different way males and females. In particular, HDL-C that was higher in non-smoker females (59 (28) mg/dL) than in non-smoker males (46 (14) mg/dL) significantly decreased in smoker females (51 (13) mg/dL), remaining unchanged in the smoker male population (42 (12) mg/dL). Conversely LDL-C, which gave similar values for non-smoker females (110.1 ± 35.2 mg/dL) and males (98.5 ± 36.0 mg/dL), increased exclusively in smoker males (122.2 ± 36.4 mg/dL, p<0.05). In turn, the level of serum antioxidants that was higher in non-smoker males (1.9 0.3 mM FRAP) than females (1.5 0.4 mM /FRAP), remained unchanged in smokers. Similar results were obtained for carbonyls, which showed higher levels in non-smoker males (0.90 ± 0.32 nmol/mg of protein) than females (0.74 ± 0.32 nmol/mg of protein), and while the level remained unmodified in smokers males (0.86 0.28 nmol/mg of protein) increased non-significantly in smoker females (0.79 0.31 nmol/mg of protein). Whereas the oxidation index correlated positively with LDL-C (r = 0.45) in smoker males, and with triglycerides in both non-smoker and smoker females(r = 0.42 and 0.79, respectively), a negative and intense correlation with HDL-C (r = -0.79), and a positive one with the LDL-C/HDL-C index (r = 0.87) was observed exclusively in smoker females. Our results point to an association at the molecular level between oxidative stress footprints and plasma lipoprotein/cholesterol concentration predominantly in smoker females, and support the concept that the higher sensitivity of women to smoking related cardiovascular pathology is associated with oxidants-mediated biomolecular insults.
Abstract: Profuse epidemiological evidence supports a higher risk for coronary heart disease and stroke in smoker women than in men with the same habit. Although it is already known that cigarette smoking alters the redox state, is unknown if the imbalance in the normal equilibrium between oxidants and antioxidants is responsible for the elevated female susc...
Show More
-
Prevalence of Abnormal Hemoglobin in Gendarmerie Barracks in Abidjan, Cote D’Ivoire
Sekongo Y. M.,
Kouamenan S.,
Siransy B. L.,
Ouattara B.,
Konan S.,
Dembele B.,
Tolo D.A.,
Hyda J.,
Kabore S.,
Konate S.
Issue:
Volume 1, Issue 3, November 2013
Pages:
58-61
Received:
20 November 2013
Published:
10 January 2014
Abstract: In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integration into an army corps those are asymptomatic blood donors. This prospective and descriptive study took place in a gendarmerie barracks in Abidjan, Ivory Coast, from October 01, 2011 to December 31, 2011. All candidates for inclusion in the corps army, aged 18 to 25 years, ivorian, from all regions of the Ivory Coast, were included in the study.EDTA tubes for Celluloseacetate electrophoresisat alkaline pHandblood count and dry tube for biochemical and virological testswere taken during donations. A total of 9526 were enrolled in this study. The median age of our patients with abnormal hemoglobins was 23 years with extremes of 18 and 25. The overall prevalence of abnormal hemoglobins was 15.07%. The prevalence was 9.54%, forHbS5,6 % for HbC and 0.052% for beta-thalassemia profile.The heterozygous AS (61.56%) and AC (35.38%), predominated. We noted 25 cases of sickle cell disease, including 14 major cases (0.97%) of homozygous SS and 11 cases (0.77%) of double heterozygous SC. We also noted 14 cases (0.97%) for CC homozygotes. The beta-thalassemia profile was weakly present in 0.35%.This study ofasymptomatic adults population, confirmed the high prevalence of HbS in Ivory Coast and the lack of a national program to fight against sickle cell disease. This should motivate the introduction of screening for abnormal hemoglobins to all the blood donors in Côte d’Ivoire
Abstract: In Ivory Coast, Sickle cell disease is a public health problem. Approximately, there are 98,000 blood donors annually to the national blood transfusion center. Among these, some holders of abnormal hemoglobins are often diagnosed. The objective of this study is to determine the prevalence of abnormal hemoglobins during a mass balance for the integr...
Show More
