American Journal of Clinical and Experimental Medicine

Volume 1, Issue 1, July 2013

  • Toxicity Effects of Amlodipine on the Body Weight and Sperm Count in Adult Wistar Rats

    Huthman Ibrahim Oluwaseun, Ibrahim Bilikis, Huthman Adebukola Selimot, Otulana Jibril

    Issue: Volume 1, Issue 1, July 2013
    Pages: 1-4
    Received: 30 April 2013
    Published: 10 June 2013
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    Abstract: Amlodipine is one of the calcium channel blocker class of antihypertensive used in the treatment of hypertension. Amlodipine is widely used in Nigeria today as an antihypertensive although the side effect on health has been reported, based on researches done. This study was carried out to appraise the toxicity effects of Amlodipine on the body weig... Show More
  • Studying Group Behaviour: Cluster Randomized Clinical Trials

    Charles J. Kowalski, Adam J. Mrdjenovich

    Issue: Volume 1, Issue 1, July 2013
    Pages: 5-15
    Received: 16 May 2013
    Published: 10 June 2013
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    Abstract: Cluster randomized trials (CRTs) are experiments in which clusters of persons, rather than the persons themselves, are randomized to receive one of the interventions being studied. The use of CRTs has been increasing in response to the attention being paid to pragmatic as opposed to explanatory clinical trials, comparative effectiveness research, a... Show More
  • Effect of Polyols P-5003-AC, P-373-2-20, P-294-2-35 on the Sanitary Regime of Water Reservoirs and Organoleptic Properties of Water in Connection with the Water Reservoirs Protection

    Zhukov V., Zaytseva O., Rezunenko Y. K., Telegin V., Bondarenko M., Knigavko V.

    Issue: Volume 1, Issue 1, July 2013
    Pages: 16-19
    Received: 14 May 2013
    Published: 30 June 2013
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    Abstract: Xenobiotics effects on the organoleptic properties of water and sanitary regime of water reservoirs had been studied by estimation of their stability and transformation in aqueous medium. Limiting indicators was revealed for substantiation of threshold concentration for the purpose of development of hygiene regulations.
  • Clinical Aspects of Juvenile Idiopathic Arthritis: Extended Experience from Bangladesh

    Shahana A Rahman, Mohammad Imnul Islam, Manik Kumar Talukder

    Issue: Volume 1, Issue 1, July 2013
    Pages: 20-23
    Received: 13 June 2013
    Published: 10 July 2013
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    Abstract: Objectives: To assess the different clinical aspects of JIA patients as well as the disease activity status during follow-up period. This study also compared its findings with the previous baseline study done in our country. Methodology: A prospective observational study carried out in the department of pediatrics, Bangabandhu Sheikh Mujib Medical ... Show More
  • Composite Endpoints: Sometimes More than a Solely Economic Consideration

    Charles J Kowalski

    Issue: Volume 1, Issue 1, July 2013
    Pages: 24-34
    Received: 18 June 2013
    Published: 20 July 2013
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    Abstract: Endpoints are response variables, or outcomes, that are measured during the course of a clinical trial. I consider endpoints that are either events (e.g., death) or the time to an occurrence of an event (e.g., time to disease progression). A composite endpoint (CEP) is an endpoint that consists of a number of component endpoints, and is considered ... Show More