American Journal of Clinical and Experimental Medicine

Volume 7, Issue 5, September 2019

  • Electrophysiology of Seizure Disorders May Hold Key to the Pathophysiology of Psychiatric Disorders

    Michael Raymond Binder

    Issue: Volume 7, Issue 5, September 2019
    Pages: 103-110
    Received: 20 August 2019
    Accepted: 20 September 2019
    Published: 30 September 2019
    Abstract: Despite the increasing burden of mental illness, social stigma and fears that psychological and emotional problems are a sign of character weakness prevent most sufferers from seeking treatment. These barriers are reinforced by diagnostic ambiguity, frequent drug side effects, variable treatment success, and a lack of clarity about the cause of men... Show More
  • Effect of “Nourishing Yin and Qi, Promoting Blood Circulation and Detoxification” on Endoplasmic Reticulum Stress CHOP Apoptotic Bypass in Diabetic Atherosclerosis

    Fu Xianzhao, Li Chunyan, Huang Wenhua, Li Xingchan, Qiu Haixian, Huang Guangming, Cao Qiuxia, Lu Mian

    Issue: Volume 7, Issue 5, September 2019
    Pages: 111-118
    Received: 19 September 2019
    Accepted: 28 September 2019
    Published: 15 October 2019
    Abstract: To explore the mechanism of Huoxue Jiedu Jiangtang Recipe (HJJR) in alleviating endoplasmic reticulum stress (ERS) - inflammation, inhibiting ERS apoptotic bypass of CHOP and alleviating diabetic atherosclerosis (AS). Diabetic AS rats were duplicated by feeding of high lipid diet and intraperitoneal injection of streptozotocin. After diabetes model... Show More
  • Effects of shRNA Expression Vector-mediated Glutathione S-transferase P1 Gene Silencing on Prostate Cancer DU145 Cells

    Ruirui Xu, Zhufu Shao, Zhi Xiao

    Issue: Volume 7, Issue 5, September 2019
    Pages: 119-125
    Received: 23 September 2019
    Published: 18 November 2019
    Abstract: Objective: This study aims to explore the impact of silent GSTP1 gene on the proliferation activity, cell cycle and apoptotic rate of the androgen-independent prostate cancer cell strain DU145. Methods: Thirty subjects with benign prostatic hyperplasia (BPH) who had been subject to urinary surgical resection and pathological diagnosis, 30 subjects ... Show More