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Lyell Syndrome in the Pediatric Emergency Room of the University Hospital Center (UHC) Gabriel Toure
Dembele Adama,
Maiga Belco,
Cisse Mohamed Elmouloud,
Doumbia Abdoul Karim,
Cissoko Nia,
Coulibaly Oumar,
Sacko Karamoko,
Issa Amadou,
Dembele Guediouma,
Karabinta Yamoussa,
Coulibaly Yacaria,
Togo Pierre,
Sidibe Lala Ndrainy,
Konate Djeneba,
Diall Hawa Gouro,
Traore Kalirou,
Kone Oumou,
Ahamadou Ibrahim,
Diakite Abdoul Aziz,
Konare Awa,
Sylla Fatou,
Togo Boubacar
Issue:
Volume 10, Issue 3, May 2022
Pages:
106-109
Received:
14 April 2022
Accepted:
3 May 2022
Published:
12 May 2022
Abstract: Introduction: Toxic epidermal necrolysis (TEN) or Lyell syndrome is the most severe form of toxidermia. It is clinically characterised by a generalised exanthema with a skin detachment of more than 30% of the body surface area, which differentiates it from Stevens-Johnson syndrome (SJS), which affects less than 10% of the body surface area. Its management is essentially symptomatic. The aim of our study is to investigate the clinical, therapeutic and evolutionary aspects of Lyell syndrome. Materials and Method: We conducted a retrospective prospective cross-sectional and descriptive study over a period of 5 years (from 1 January 2014 to 31 December 2018). It concerned children from 1 month to 15 years old. Data were collected using a pre-established survey form and inpatient records. After informed consent from parents and the Head of Department, all information was collected in strict confidentiality. Results: During the study period, we were able to collect 10 patients meeting our inclusion criteria out of 9050 hospitalizations, or a frequency of 0.11%. The sex ratio was 4. The age group (6 months to 5 years) was the most affected with 60% of cases. Almost all patients (90%) consulted for skin lesions. The drugs frequently incriminated were non-steroidal anti-inflammatory drugs and anti-epileptics in equal proportions (20%). In 4 patients (40%), no drug could be clearly incriminated. On physical examination, NIKOLSKI's sign was found in 90% of patients. Management was essentially based on rehydration, antibiotic therapy, analgesics and local care. However, mortality remains very high (7 out of 10 patients). Conclusion: A rare but very serious pathology, Lyell syndrome has a poor prognosis in our context.
Abstract: Introduction: Toxic epidermal necrolysis (TEN) or Lyell syndrome is the most severe form of toxidermia. It is clinically characterised by a generalised exanthema with a skin detachment of more than 30% of the body surface area, which differentiates it from Stevens-Johnson syndrome (SJS), which affects less than 10% of the body surface area. Its man...
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Epidemiological and Clinical Aspects of Acute Intoxications in Children Between 1 Month and 15 Years in the Paediatric Emergency of the UHC Gabriel Toure
Dembele Adama,
Cisse Mohamed Elmouloud,
Doumbia Abdoul Karim,
Maiga Belco,
Maiga Fatoumata,
Sacko Karamoko,
Coulibaly Oumar,
Togo Pierre,
Konate Djeneba,
Diall Hawa Gouro,
Sidibe Lala Ndrainy,
Coulibaly Yacouba Aba,
Diakite Fatoumata Leonie,
Kone Younoussa Dembele Guediouma,
Kone Oumou,
Ahamadou Ibrahim,
Traore Kalirou,
Konare Awa,
Diakite Abdoul Aziz,
Togo Boubacar
Issue:
Volume 10, Issue 3, May 2022
Pages:
110-114
Received:
14 April 2022
Accepted:
3 May 2022
Published:
12 May 2022
Abstract: Introduction: Defined by the WHO as all the pathological manifestations following ingestion of food or the administration of products or drugs behaving like a poison in the body, acute intoxication is a growing problem. serious in pediatrics, in developing countries because of their frequency and the difficulties of care. In Mali, poisoning in children is very poorly assessed, in part due to the lack of popularization of poison control and pharmacovigilance centers. The objective of our study is to study the epidemiological and clinical aspects of acute poisoning in children in the emergency department of the pediatric department of the Gabriel Touré University Hospital. Material and methods: We carried out a retrospective, cross-sectional and descriptive study from January 2016 to December 2018, or a period of 3 years. It concerned children from 1 month to 15 years old hospitalized in the pediatric emergency room of the Gabriel Touré University Hospital for proven acute poisoning. The data were collected by: a pre-established individual survey form, information contained in the medical files of patients after the approval of the Head of the Department. Results: During our study period, 80 children were hospitalized for acute poisoning out of a total of 5,437, a frequency of 1.47%. The sex ratio was 1.3. The 13-48-month age group accounted for 65% of cases. The patients themselves were responsible for their poisoning in 74.2% of cases. Poisoning by unspecified drugs accounted for 25% of cases. The oral route represented 92.4% of the poisoning routes. Ingestion of milk (29.9%) and oil (6.3%) were the most common actions for parents. Vomiting with 35% and respiratory distress with 35% were the most frequent manifestations. The mean hospital stay was 3.5 days (50%). In 50% of cases, death occurred within the first 24 hours. Conclusion: Poisoning remains a common occurrence in our department, mainly linked to several medicines and household products.
Abstract: Introduction: Defined by the WHO as all the pathological manifestations following ingestion of food or the administration of products or drugs behaving like a poison in the body, acute intoxication is a growing problem. serious in pediatrics, in developing countries because of their frequency and the difficulties of care. In Mali, poisoning in chil...
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Effects of Different Absenteeism Statistical Methods on Influenza Surveillance
Zhen Yang,
Cheng-hua Jiang
Issue:
Volume 10, Issue 3, May 2022
Pages:
115-123
Received:
24 May 2022
Published:
26 May 2022
Abstract: Background The existing absenteeism surveillance systems in China rely heavily on school doctors to collect data manually, but the low prevalence rate of school doctors makes it difficult to popularize this mode. The method of absenteeism statistics requires new breakthroughs. Objective The purpose of this study was to evaluate the feasibility of an established absenteeism surveillance system based on face recognition, and to explore the appropriate surveillance index for this system. Methods A primary school of about 1900 students was selected. Absenteeisms reported by school doctors and this system from March 1, 2021 (week 9) to January 14, 2022 (week 2) were collected, as well as weekly positive rate of influenza virus (WPRIV) released by China National Influenza Center. Eight weekly absenteeism rate indicators were calculated: all-cause absenteeism rate reported by system (WAR1), all-cause absenteeism rate reported by school doctors (WAR2), sickness absenteeism rate reported by school doctors (WAR3), and the rate of students absent one time (WAR4), two times (WAR5), three to four times (WAR6), one to two times (WAR7) and two to four times (WAR8) a week reported by the system. Pearson correlation coefficients of eight indicators and WPRIV were analyzed, and the change trend of their time series diagram was investigated. Results During week 9-42, WAR1 (r=0.614, p=0.001), WAR4 (r=0.631, p<0.001), WAR5 (r=0.651, p<0.001), WAR6 (r=0.541, p<0.001), WAR7 (r=0.654, p<0.001) and WAR8 (r=0.644, p<0.001) were significantly correlated with WPRIV, while WAR2 (r=0.262, p>0.05) and WAR3 (r=0.239, p>0.05) were not. Throughout the surveillance period, WAR1 (r=0.671, p<0.001), WAR2 (r=0.638, p<0.001), WAR3 (r=0.752, p<0.001), WAR5 (r=0.682, p<0.001), WAR6 (r=0.535, p<0.001) and WAR8 (r=0.683, p<0.001) were significantly correlated with WPRIV, while WAR4 (r=0.086, p>0.05) and WAR7 (r=0.242, p>0.05) were not. Conclusions Absenteeism reported by the system was more effective for influenza surveillance than absenteeism reported by school doctors, especially when the influenza activity level was low. When WAR1, WAR5 and WAR8 were combined together, the epidemic situation of influenza could be more comprehensively aware.
Abstract: Background The existing absenteeism surveillance systems in China rely heavily on school doctors to collect data manually, but the low prevalence rate of school doctors makes it difficult to popularize this mode. The method of absenteeism statistics requires new breakthroughs. Objective The purpose of this study was to evaluate the feasibility of a...
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IoT Drone Technology Integration in Medical Logistics Delivery
Janet Folasade Taiwo,
Okochi Ijeoma Prisca,
Ugochukwu Okwudili Matthew,
Amaonwu Onyebuchi,
Ubochi Chibueze Nwamouh,
Ugochukwu Iheruo Robert,
Ani Okechukwu Matthew
Issue:
Volume 10, Issue 3, May 2022
Pages:
124-133
Received:
14 February 2022
Accepted:
21 March 2022
Published:
31 May 2022
Abstract: Drone technology has linked up several opportunities to enable direct connection with the medical consumable donors to receive request through mobile phone communication and deliver medical consumables via Drone device. The recent development in autonomous air navigation and implementation of Drones into mainstream geographical ecosystem have been recognized for adoption in healthcare emergency responses. At the center of the innovation is the Internet of Things (IoT) technology which had necessitated advanced mission specification for Drones to operate beyond visually line of sight (BVLOS) in responding to classified healthcare assignments. The use of Drones in the healthcare management, welfare support, emergency responses and health risk management was investigated in the selected country of the Central East Africa (Rwanda). The research discovered a system of dynamic connection between the tiers of governments in active partnership with the private sector initiative to exploit Drone technology innovation to improve healthcare service delivery up to the grass root level with an outstanding productivity. The article evaluated Africa’s involvement in the society healthcare extreme automation using Drone technology capabilities and deliberated on the possibilities and benefits for implementation and adoption into the national healthcare sector in Nigeria. The paper concluded that future implementation of the research will accomplish the digital health demands of Nigeria government, public and private sector health maintenance to guarantee sustainable healthcare investment and effective healthcare service delivery.
Abstract: Drone technology has linked up several opportunities to enable direct connection with the medical consumable donors to receive request through mobile phone communication and deliver medical consumables via Drone device. The recent development in autonomous air navigation and implementation of Drones into mainstream geographical ecosystem have been ...
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Bibliometric Analysis of Publication Hot Topics of Smartphones in the Field of Health and Medical Services
Zhiqiang Tian,
Yanjun Wang,
Jiao Lu,
Li Song,
Jianzhong Zheng
Issue:
Volume 10, Issue 3, May 2022
Pages:
134-141
Received:
31 May 2022
Published:
1 June 2022
Abstract: Smartphones have captured the attention of many health- and medical-services researchers. This study aimed to quantify research ‘hotspots’ in this field, analyse the relationship between research hotspots and the resulting knowledge groups, and provide visual representations of the findings. Using bibliometric analysis software tools for keyword frequency analysis, research hotspots were identified using keywords from PubMed entries from a 14-year period. The analyses of hotspots were performed using keyword co-occurrence analysis, social network analysis, principal component analysis, multidimensional scaling analysis, and network visualization technology. The results confirmed that the number of articles have been increasing each year. The topics of mobile applications, telemedicine, self-care, Diabetes Mellitus, treatment outcomes, health promotion, and patient satisfaction associated with smartphones were highlighted. The 35 high-frequency keywords that were extracted constituted five principal components of research related to information technology and telemedicine, diabetes, t-health promotion, and smartphones/handheld computers. Figures of knowledge network maps and perceptual maps show the relationship between the high-frequency keywords. Research hotspots for smartphone-related information technology, telemedicine, and health promotion have broad prospects for development. This study provides directions for research hotspots and future research in the field of smartphone applications for health and medical services.
Abstract: Smartphones have captured the attention of many health- and medical-services researchers. This study aimed to quantify research ‘hotspots’ in this field, analyse the relationship between research hotspots and the resulting knowledge groups, and provide visual representations of the findings. Using bibliometric analysis software tools for keyword fr...
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A Systematic Review and Meta-analysis of the Efficacy of Medical Masks and N95 Respirators for Protection Against Respiratory Infectious Diseases
Gaohong Wu,
Qingyang Ji,
Huiwen Huang,
Xueping Zhu
Issue:
Volume 10, Issue 3, May 2022
Pages:
142-157
Received:
12 May 2022
Accepted:
13 June 2022
Published:
16 June 2022
Abstract: To evaluate the efficacy of N95 respirators and medical masks for protection against respiratory infectious diseases, including COVID-19. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) and observational studies evaluating the use of N95 respirators and medical masks for protection against respiratory infectious diseases. We retrieved relevant articles published from January 1994 to January 2020 by searching the PubMed, EMBASE, Cochrane CENTRAL, and Web of Science databases. The study quality was evaluated using the Cochrane Risk of Bias tool with RevMan 5.3 software. Eleven RCTs adjusted for clustering were included in the meta-analysis. Compared with the control group, N95 respirators or medical masks conferred significant protection against respiratory infectious diseases (odds ratio (OR) = 0.20; 95% CI: 0.08–0.51). Compared to medical masks, N95 respirators conferred significant protection against respiratory infectious diseases (OR = 0.75; 95% confidence interval (CI): 0.57–0.99). Meta-analysis of 10 observational studies adjusting for clustering also suggested that N95 respirators and medical masks are effective for protection against respiratory infectious diseases (OR = 0.30; 95% CI: 0.15–0.63). Given the body of evidence through a systematic review and meta-analyses, our findings supported the use of N95 respirators or medical masks has a significantly greater protective effect against respiratory infectious diseases among medical workers compared with those who did not use these types of PPE. However, only one case report showed the effectiveness of medical masks for preventing COVID-19. Although medical masks and N95 respirators may confer significant protection against respiratory infectious diseases, there is insufficient evidence to conclude that these types of personal protective equipment offer similar protection against COVID-19. Moreover, in the absence of sufficient resources during an epidemic, medical masks and N95 respirators should be reserved for high-risk, aerosol-generating producing procedures.
Abstract: To evaluate the efficacy of N95 respirators and medical masks for protection against respiratory infectious diseases, including COVID-19. We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) and observational studies evaluating the use of N95 respirators and medical masks for protection against respiratory infec...
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