Advances in Biochemistry

Volume 13, Issue 3, September 2025

  • Research Article

    Gastroprotective and Antigastric Ulcer Effects of the Methanol Fraction of Cleistopholis Patens Leaves on Two Ulcer Models in Rats

    Nnamani Ikenna, Parker Joshua*, Ikechukwu Okoro, Innocent Okagu, Victor Ogugua

    Issue: Volume 13, Issue 3, September 2025
    Pages: 61-78
    Received: 14 March 2025
    Accepted: 26 March 2025
    Published: 4 July 2025
    DOI: 10.11648/j.ab.20251303.11
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    Abstract: Background: Cleistopholis patens leaves are used to treat stomach disorders in Nigeria. This research investigated the gastroprotective and antigastric ulcer effects of the methanol fraction of Cleistopholis patens leaves (MFCPL) in rats. Methods: In vitro experiments involved DPPH-radical scavenging and H+/K+-ATPase inhibitory activities. Two ulce... Show More