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Establishment of Microbial Limit Test Assay for Traditional Mongolian Medicine ShaoSha-7 Pills
Song Fushun,
Seyinbaoyin,
Caolungaowa,
Aodongtana,
Bao Siqin,
Alatengqimuge,
Wuhanqimuge
Issue:
Volume 1, Issue 1, December 2018
Pages:
1-5
Received:
17 August 2018
Accepted:
18 December 2018
Published:
20 December 2018
Abstract: This study is aimed at establishing the Microbiological standard for ShaoSha-7 pills by referring to the general provisions 1105 and 1106 of part IV of “Chinese pharmacopoeia” 2015 edition, and supplying the data for improving the quality and ensuring the medical effect of ShaoSha-7 pills. Routine essay, dilution method，membrane-filter procedure and quantitative method were used to examine the microbial of ShaoSha-7 pills and the system suitability of experimental method was tested. Results showed that the recovery for the total number of strains (Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Monilia albican, Aspergillus niger) was 88-127% when membrane-filter method was used, and the recovery for fungus and yeasts was 87-120% while the bacteria was counted by routine method. Both recoveries met the requirement of pharmacopoeia. For the control strains experiment, Escherichia coli and Salmonella paratyphi B of ShaoSha-7 pills were detectable through routine method, and Bile salt resistant gram-negative bacteria of ShaoSha-7 pills was detectable by quantitative assay, respectively. Meanwhile, no strains were observed in the negative control of both cases, indicating the methods were feasible. Finally, the assay for checking microbial of ShaoSha-7 pills was initially established based on the above results. It supplies the data for setting up the quality control standard, especially microbiological standard for ShaoSha-7 pills.
Abstract: This study is aimed at establishing the Microbiological standard for ShaoSha-7 pills by referring to the general provisions 1105 and 1106 of part IV of “Chinese pharmacopoeia” 2015 edition, and supplying the data for improving the quality and ensuring the medical effect of ShaoSha-7 pills. Routine essay, dilution method，membrane-filter procedure an...
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Memory Alloy Clamp in the Treatment of Patella Fracture
Yang Bin,
Li Zhijin,
Yang Xiaojun,
Chen Guohui,
Xu Linlin
Issue:
Volume 1, Issue 1, December 2018
Pages:
6-9
Received:
22 August 2018
Accepted:
3 December 2018
Published:
21 December 2018
Abstract: Objective: To explore the therapeutic effects of the treatment of patella fracture with memory alloy clamp fixation. Methods: A retrospective review of 78 patients with patella fractures and received memory alloy clamp fixation admitted to our department in the past 24 months in 2016 was performed. The operation time, postoperative complications and recovery of postoperative knee function were collected and analyzed. Results: All patients were followed up for a minimum of 6 months. The operation time was 40-90 minutes, with an average of 60 minutes. All the patients were healed in the first stage except one elderly patient who develops incision infection. After active debridement and usual dressing change, the patient finally recovered without internal fixation remove. All patients got an ideal knee function recovery after operation. According to the classification criteria of the Hospital for Special Surgery (HSS), 69 cases were excellent, 6 cases were good, 2 cases were normal, and 1 case was poor. Conclusion: The memory alloy clamp is an ideal internal fixation method for the treatment of patella fracture, with the advantages of simple operation, good histocompatibility, dynamic-stereoscopic continuous compression, conformity to the tension band principle, no need for external fixation with plaster, ideal knee joint function recovery, which worthy of clinical population.
Abstract: Objective: To explore the therapeutic effects of the treatment of patella fracture with memory alloy clamp fixation. Methods: A retrospective review of 78 patients with patella fractures and received memory alloy clamp fixation admitted to our department in the past 24 months in 2016 was performed. The operation time, postoperative complications an...
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A Case of Addison's Disease with Only Progressive Skin Pigmentation
Lingji Zeng,
Zhongye Chen
Issue:
Volume 1, Issue 1, December 2018
Pages:
10-13
Received:
14 September 2018
Accepted:
3 December 2018
Published:
4 January 2019
Abstract: A 47 years old woman presented with darkening skins on exposed and frictional areas for more than one year, in addition to fatigue, loss of appetite and weight loss for 2 months. One year ago, there was no inducement of pigmentation on the back of the hand, and it spread to the elbow. Then, the skin of the chest, lower limbs, abdomen, neck, forehead, and internal eyelids also gradually appeared diffuse dark spots. Meanwhile she had low 24-hour urinary excretion of 17-hydroxy steroid and increased ACTH. X-ray test showed point-like calcification shadow on bilateral lungs; CT test showed increased adrenal gland volume, substantially uninformed density, and multiple stippled calcification. Histopathological results: Chromatophilic cells and macrophages that were arranged in nests, scattered and pigment-laden can see subepidermally. Diagnosis: Addison’s disease. After 6 months anti-TB and glucocorticoid hormone replacement therapy, the patient had a good general condition, disappeared clinical symptoms as well as laboratory and imaging test results returned to normal. Now no drugs have been administrated except for 2.5mg of prednisone tablets to take at a draught every morning. The patient is still traced and observed. The study in this case suggests that clinicians should be highly vigilant against Addison's disease in patients who are treated with multiple skin progressive pigmentation.
Abstract: A 47 years old woman presented with darkening skins on exposed and frictional areas for more than one year, in addition to fatigue, loss of appetite and weight loss for 2 months. One year ago, there was no inducement of pigmentation on the back of the hand, and it spread to the elbow. Then, the skin of the chest, lower limbs, abdomen, neck, forehea...
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Pyruvate Application Indicates an Important Medical Advance
Issue:
Volume 1, Issue 1, December 2018
Pages:
14-20
Received:
6 November 2018
Accepted:
3 January 2019
Published:
4 January 2019
Abstract: On the occasion of the 50th anniversary of WHO-guided oral rehydration salts (ORS) clinical application, this review mainly discussed recent findings in ORS, a novel pyruvate-enriched ORS (Pyr-ORS), in animal experiments. Since past several decades, numerous pieces of evidence have shown that pyruvate owns superior biological and pharmacological characteristics that benefit critical care patients: enhancement of anoxia/hypoxia tolerance, correction of hypoxic lactic acidosis, antagonism of oxidative stress and inflammation, protection of mitochondrial structure and function and anti-apoptosis, etc. Therefore, pyruvate prevents from multi-organ dysfunction and corrects disturbances of glucose metabolism and acid-base balance in patients subjected with various pathogen insults. In recent years, investigations of intravenous pyruvate and oral pyruvate in ORS demonstrated properties above and a double increase of survival in animals subjected to hemorrhagic or burn shock. In the review, biological properties of pyruvate and the high efficiency, underlying mechanisms and vast potential clinical indications of Pyr-ORS were illustrated. The review points out that pyruvate-enriched fluids may be the third generation of fluid therapy, not only a volume expander, but also a therapeutic agent for organ dysfunction and metabolic disturbance; pyruvate may be the first-line drug for fluid therapy: Pyr-ORS becomes the first choice for patients who require fluid rehydration alone or in combination with intravenous pyruvate. Pyruvate applications would improve overall clinical outcomes of various diseases, particularly critical illnesses, potentiating a new most important medical advance this century.
Abstract: On the occasion of the 50th anniversary of WHO-guided oral rehydration salts (ORS) clinical application, this review mainly discussed recent findings in ORS, a novel pyruvate-enriched ORS (Pyr-ORS), in animal experiments. Since past several decades, numerous pieces of evidence have shown that pyruvate owns superior biological and pharmacological ch...
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Application of Thermostat Heating Contrast Agent to Improve Nursing Satisfaction Rate of MSCT Enhancement
Li Ruixiong,
Xu Wanling,
Zhou Qi,
Liu Shaoying,
Deng Jinqun
Issue:
Volume 1, Issue 1, December 2018
Pages:
21-23
Received:
15 September 2018
Accepted:
17 September 2019
Published:
5 January 2019
Abstract: Objective to explore the effect of thermostat heated injection contrast agent on nursing satisfaction in multi-slice spiral CT (MSCT) enhancement. Methods 456 patients who underwent enhanced CT examination in the Radiology Department of People's Hospital from September 2017 to January 2018 were randomly divided into control group and research group.The study group used the contrast agent heated by the thermostat, while the control group used the contrast agent at room temperature, The adverse reactions of the two groups were compared, and comfort and nursing satisfaction were investigated. Results There were 2 mild adverse reactions both in the study group and the control group, and no moderate or more adverse reactions occurred. The nursing satisfaction of the study group was 94%, while that of the control group was 82%, and the difference between the two groups was statistically significant. (P<0.01). Conclusion In MSCT enhanced scanning, the use of thermostat heated injection contrast agent can alleviate the discomfort of patients and improve nursing satisfaction, which is worthy of promotion.
Abstract: Objective to explore the effect of thermostat heated injection contrast agent on nursing satisfaction in multi-slice spiral CT (MSCT) enhancement. Methods 456 patients who underwent enhanced CT examination in the Radiology Department of People's Hospital from September 2017 to January 2018 were randomly divided into control group and research group...
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