American Journal of Internal Medicine

Volume 4, Issue 4, July 2016

  • Association Between Soluble CD40L with Thrombosis Occurrence and JAK2 V617F Mutation in Essential Thrombocythemia

    Wafaa S. Mohammed, Wael A. Abbas, Ola A. Afifi, Ahmad F. Thabet

    Issue: Volume 4, Issue 4, July 2016
    Pages: 60-65
    Received: 2 May 2016
    Accepted: 21 May 2016
    Published: 4 June 2016
    Abstract: Thrombo-haemorrhagic events are the main cause of mortality in essential thrombocythemia (ET). The aim of this study was to measure soluble CD40 ligand (sCD40L) in the plasma of healthy individuals and in patients with an elevated platelet count and investigate the association of sCD40L with thrombosis in ET patients and their JAK2 V617F mutation. ... Show More
  • Treatment with Tyrosine Kinase Inhibitors in Chronic Myeloproliferative Neoplasms: Pros and Cons

    Safaa A. A. Khaled

    Issue: Volume 4, Issue 4, July 2016
    Pages: 66-74
    Received: 10 June 2016
    Accepted: 20 June 2016
    Published: 4 July 2016
    Abstract: Myeloproliferative neoplasms (MPNs) are a group of hematological disorders characterized by proliferation of one or more than one myeloid lineage. Genetically they express single or multiple mutations of the Janus tyrosine kinase receptors. Advances in understanding molecular and cytogenetic pathophysiology of MPNs led to further identification of ... Show More
  • Mortality in a Primary and Secondary Transported of STEMI Patients, a Prospective Study

    Al Mawiri A., Stasek J., Vojáček J., Bis J., Albahri Z.

    Issue: Volume 4, Issue 4, July 2016
    Pages: 75-78
    Received: 30 June 2016
    Accepted: 19 July 2016
    Published: 29 July 2016
    Abstract: In ST-elevation myocardial infarction (STEMI), the pre-hospital phase is the most critical and appropriate treatment in a timely manner which is instrumental for mortality reduction. STEMI systems of care based on networks of medical institutions connected by an efficient emergency medical service (EMS) are pivotal. The first steps are devoted to m... Show More