International Journal of Genetics and Genomics

Volume 11, Issue 4, December 2023

  • Research Article

    Y-Chromosome Microdeletion Screening in Senegalese Infertile Men

    Adji Dieynaba Diallo*, Arame Ndiaye, Fatou Diop Gueye, Ndiaga Diop, Rokhaya Ndiaye, Amath Thiam, Abdoulaye Sega Diallo, Mame Venus Gueye, Mama Sy Diallo, Oumar Faye

    Issue: Volume 11, Issue 4, December 2023
    Pages: 112-118
    Received: Sep. 21, 2023
    Accepted: Oct. 20, 2023
    Published: Nov. 30, 2023
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    Abstract: Background: Significant progress has been made in recent years towards understanding the pathogenesis of spermatogenic arrest and infertility. Genetic factors contribute to 10-15% of male infertility. After chromosomal abnormalities, Azoospermia factor (AZF) microdeletions in the Yq region are the second most prevalent spermatogenic disorder among ... Show More
  • Research Article

    Genetic Variability in Sesame (Sesamum indicum L.) Genotypes for Shattering and Shattering-Related Traits

    Sintayehu Gedifew

    Issue: Volume 11, Issue 4, December 2023
    Pages: 119-125
    Received: Sep. 25, 2023
    Accepted: Oct. 24, 2023
    Published: Nov. 30, 2023
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    Abstract: Shattering has a substantial yield reduction in sesame. Sixty-four sesame genotypes were evaluated using 8 x 8 lattice design with two replications at the main research station of Pawe Agricultural Research Center to assess the genetic variability among sesame genotypes for shattering and shattering-related traits. Data were collected on days to fi... Show More
  • Research Article

    Evaluation of Food Barley (Hordeum vulgare L.) Varieties at Highlands of Southwestern Part of Ethiopia Using AMMI and GGE Biplot Stability Models

    Tegegn Belete

    Issue: Volume 11, Issue 4, December 2023
    Pages: 126-132
    Received: Nov. 13, 2023
    Accepted: Nov. 30, 2023
    Published: Dec. 08, 2023
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    Abstract: A multi location trial was conducted across the highlands of Southwestern (SW) Ethiopia from 2020 to 2022 during main cropping seasons to evaluate grain yield and yield related traits of food barley varieties across the different locations to identify and recommend high yielding and stable food barley varieties to farmers for large scale planting u... Show More
  • Research Article

    Construction of a Cuproptosis-Related Gene Clinical Prediction Model for Juvenile Idiopathic Arthritis Using Machine Learning

    Yiwei Hong, Xu Cai, Xinpeng Chen, Xinmin Huang, Zhengbo Yan, Peihu Li, Jianwei Xiao*

    Issue: Volume 11, Issue 4, December 2023
    Pages: 133-138
    Received: Nov. 23, 2023
    Accepted: Dec. 07, 2023
    Published: Dec. 22, 2023
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    Abstract: Objective: Juvenile Idiopathic Arthritis (JIA) is a chronic inflammatory joint disease affecting children and adolescents, where early diagnosis and treatment are crucial for improving prognosis. This study aimed to identify cuproptosis-related genes in JIA and develop a clinical predictive model. Methods: The GSE13849 dataset was retrieved from th... Show More