Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of <i>Tropaeolum tuberosum</i> (Ruiz & Pav.) Kuntze (Tropaeolaceae)

Jiménez-Heinert María Elena; Gutiérrez-Gaitén Yamilet Irene; Chóez-Guaranda Iván; Miranda-Martínez Migdalia

doi:doi:10.11648/j.ijpc.20200604.12

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Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae)

Jiménez-Heinert María Elena, Gutiérrez-Gaitén Yamilet Irene, Chóez-Guaranda Iván, Miranda-Martínez Migdalia

Published in International Journal of Pharmacy and Chemistry (Volume 6, Issue 4)

Received: 16 July 2020 Accepted: 10 August 2020 Published: 25 August 2020

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Abstract

Ecuador has among its foods a series of potatoes and tubers that are not only nutritious, but also contain properties such as adjuvants which aid in the treatment of diseases caused by an inflammatory state. However, there is a lack of scientific evidence to support these hypotheses. The objective of this study was to carry out a comparative study of two varieties of the mashua tuber (Tropaeolum tuberosum spp tuberosum (Ruíz & Pavón, Kuntze)), by analyzing the pharmacognostic, chemical and anti-inflammatory characteristics. Since there are no previous reports regarding the macro- and micromorphological characteristics of the tubers, the following analyses were conducted; the establishment of physical-chemical parameters, the qualitative determination of the secondary metabolites, the quantification of phenols as well as flavonoids and the characterization of the extracts of ethyl acetate, ethyl alcohol and the coupling of the system through gas chromatography-mass spectrometry. Significant differences were found in the macro- and micromorphology, as well as in the secondary metabolite between the two varieties studied. The black mashua showed a higher concentration quantification of phenols and flavonoids. Some phytosterols and triterpenoids were reported for the first time in these species and the anti-inflammatory activity of the tubers was demonstrated. These findings can lead to further research for a future use in a clinical trial.

Published in	International Journal of Pharmacy and Chemistry (Volume 6, Issue 4)
DOI	10.11648/j.ijpc.20200604.12
Page(s)	41-53
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Anti-Inflammatory, Chemical Composition, Macro and Micromorphology

References

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Jiménez-Heinert María Elena, Gutiérrez-Gaitén Yamilet Irene, Chóez-Guaranda Iván, Miranda-Martínez Migdalia. (2020). Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). International Journal of Pharmacy and Chemistry, 6(4), 41-53. https://doi.org/10.11648/j.ijpc.20200604.12

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Jiménez-Heinert María Elena; Gutiérrez-Gaitén Yamilet Irene; Chóez-Guaranda Iván; Miranda-Martínez Migdalia. Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). Int. J. Pharm. Chem. 2020, 6(4), 41-53. doi: 10.11648/j.ijpc.20200604.12

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AMA Style

Jiménez-Heinert María Elena, Gutiérrez-Gaitén Yamilet Irene, Chóez-Guaranda Iván, Miranda-Martínez Migdalia. Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). Int J Pharm Chem. 2020;6(4):41-53. doi: 10.11648/j.ijpc.20200604.12

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@article{10.11648/j.ijpc.20200604.12,
  author = {Jiménez-Heinert María Elena and Gutiérrez-Gaitén Yamilet Irene and Chóez-Guaranda Iván and Miranda-Martínez Migdalia},
  title = {Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae)},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {6},
  number = {4},
  pages = {41-53},
  doi = {10.11648/j.ijpc.20200604.12},
  url = {https://doi.org/10.11648/j.ijpc.20200604.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20200604.12},
  abstract = {Ecuador has among its foods a series of potatoes and tubers that are not only nutritious, but also contain properties such as adjuvants which aid in the treatment of diseases caused by an inflammatory state. However, there is a lack of scientific evidence to support these hypotheses. The objective of this study was to carry out a comparative study of two varieties of the mashua tuber (Tropaeolum tuberosum spp tuberosum (Ruíz & Pavón, Kuntze)), by analyzing the pharmacognostic, chemical and anti-inflammatory characteristics. Since there are no previous reports regarding the macro- and micromorphological characteristics of the tubers, the following analyses were conducted; the establishment of physical-chemical parameters, the qualitative determination of the secondary metabolites, the quantification of phenols as well as flavonoids and the characterization of the extracts of ethyl acetate, ethyl alcohol and the coupling of the system through gas chromatography-mass spectrometry. Significant differences were found in the macro- and micromorphology, as well as in the secondary metabolite between the two varieties studied. The black mashua showed a higher concentration quantification of phenols and flavonoids. Some phytosterols and triterpenoids were reported for the first time in these species and the anti-inflammatory activity of the tubers was demonstrated. These findings can lead to further research for a future use in a clinical trial.},
 year = {2020}
}

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TY  - JOUR
T1  - Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae)
AU  - Jiménez-Heinert María Elena
AU  - Gutiérrez-Gaitén Yamilet Irene
AU  - Chóez-Guaranda Iván
AU  - Miranda-Martínez Migdalia
Y1  - 2020/08/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ijpc.20200604.12
DO  - 10.11648/j.ijpc.20200604.12
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 41
EP  - 53
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20200604.12
AB  - Ecuador has among its foods a series of potatoes and tubers that are not only nutritious, but also contain properties such as adjuvants which aid in the treatment of diseases caused by an inflammatory state. However, there is a lack of scientific evidence to support these hypotheses. The objective of this study was to carry out a comparative study of two varieties of the mashua tuber (Tropaeolum tuberosum spp tuberosum (Ruíz & Pavón, Kuntze)), by analyzing the pharmacognostic, chemical and anti-inflammatory characteristics. Since there are no previous reports regarding the macro- and micromorphological characteristics of the tubers, the following analyses were conducted; the establishment of physical-chemical parameters, the qualitative determination of the secondary metabolites, the quantification of phenols as well as flavonoids and the characterization of the extracts of ethyl acetate, ethyl alcohol and the coupling of the system through gas chromatography-mass spectrometry. Significant differences were found in the macro- and micromorphology, as well as in the secondary metabolite between the two varieties studied. The black mashua showed a higher concentration quantification of phenols and flavonoids. Some phytosterols and triterpenoids were reported for the first time in these species and the anti-inflammatory activity of the tubers was demonstrated. These findings can lead to further research for a future use in a clinical trial.
VL  - 6
IS  - 4
ER  -

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Author Information

Jiménez-Heinert María Elena

Faculty of Chemical Sciences, University of Guayaquil, Guayaquil, Ecuador
Gutiérrez-Gaitén Yamilet Irene

Pharmacy and Food Institute, University of Havana, Havana, Cuba
Chóez-Guaranda Iván

Biotechnological Research Center of Ecuador, Polytechnic Superior School of the Littoral, Guayaquil, Ecuador
Miranda-Martínez Migdalia

Biotechnological Research Center of Ecuador, Polytechnic Superior School of the Littoral, Guayaquil, Ecuador

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Jiménez-Heinert María Elena, Gutiérrez-Gaitén Yamilet Irene, Chóez-Guaranda Iván, Miranda-Martínez Migdalia. (2020). Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). International Journal of Pharmacy and Chemistry, 6(4), 41-53. https://doi.org/10.11648/j.ijpc.20200604.12

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ACS Style

Jiménez-Heinert María Elena; Gutiérrez-Gaitén Yamilet Irene; Chóez-Guaranda Iván; Miranda-Martínez Migdalia. Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). Int. J. Pharm. Chem. 2020, 6(4), 41-53. doi: 10.11648/j.ijpc.20200604.12

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AMA Style

Jiménez-Heinert María Elena, Gutiérrez-Gaitén Yamilet Irene, Chóez-Guaranda Iván, Miranda-Martínez Migdalia. Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae). Int J Pharm Chem. 2020;6(4):41-53. doi: 10.11648/j.ijpc.20200604.12

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@article{10.11648/j.ijpc.20200604.12,
  author = {Jiménez-Heinert María Elena and Gutiérrez-Gaitén Yamilet Irene and Chóez-Guaranda Iván and Miranda-Martínez Migdalia},
  title = {Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae)},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {6},
  number = {4},
  pages = {41-53},
  doi = {10.11648/j.ijpc.20200604.12},
  url = {https://doi.org/10.11648/j.ijpc.20200604.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20200604.12},
  abstract = {Ecuador has among its foods a series of potatoes and tubers that are not only nutritious, but also contain properties such as adjuvants which aid in the treatment of diseases caused by an inflammatory state. However, there is a lack of scientific evidence to support these hypotheses. The objective of this study was to carry out a comparative study of two varieties of the mashua tuber (Tropaeolum tuberosum spp tuberosum (Ruíz & Pavón, Kuntze)), by analyzing the pharmacognostic, chemical and anti-inflammatory characteristics. Since there are no previous reports regarding the macro- and micromorphological characteristics of the tubers, the following analyses were conducted; the establishment of physical-chemical parameters, the qualitative determination of the secondary metabolites, the quantification of phenols as well as flavonoids and the characterization of the extracts of ethyl acetate, ethyl alcohol and the coupling of the system through gas chromatography-mass spectrometry. Significant differences were found in the macro- and micromorphology, as well as in the secondary metabolite between the two varieties studied. The black mashua showed a higher concentration quantification of phenols and flavonoids. Some phytosterols and triterpenoids were reported for the first time in these species and the anti-inflammatory activity of the tubers was demonstrated. These findings can lead to further research for a future use in a clinical trial.},
 year = {2020}
}

Copy | Download

TY  - JOUR
T1  - Pharmacognostic, Chemical and Anti-inflammatory Activity Study of Two Varieties of Tropaeolum tuberosum (Ruiz & Pav.) Kuntze (Tropaeolaceae)
AU  - Jiménez-Heinert María Elena
AU  - Gutiérrez-Gaitén Yamilet Irene
AU  - Chóez-Guaranda Iván
AU  - Miranda-Martínez Migdalia
Y1  - 2020/08/25
PY  - 2020
N1  - https://doi.org/10.11648/j.ijpc.20200604.12
DO  - 10.11648/j.ijpc.20200604.12
T2  - International Journal of Pharmacy and Chemistry
JF  - International Journal of Pharmacy and Chemistry
JO  - International Journal of Pharmacy and Chemistry
SP  - 41
EP  - 53
PB  - Science Publishing Group
SN  - 2575-5749
UR  - https://doi.org/10.11648/j.ijpc.20200604.12
AB  - Ecuador has among its foods a series of potatoes and tubers that are not only nutritious, but also contain properties such as adjuvants which aid in the treatment of diseases caused by an inflammatory state. However, there is a lack of scientific evidence to support these hypotheses. The objective of this study was to carry out a comparative study of two varieties of the mashua tuber (Tropaeolum tuberosum spp tuberosum (Ruíz & Pavón, Kuntze)), by analyzing the pharmacognostic, chemical and anti-inflammatory characteristics. Since there are no previous reports regarding the macro- and micromorphological characteristics of the tubers, the following analyses were conducted; the establishment of physical-chemical parameters, the qualitative determination of the secondary metabolites, the quantification of phenols as well as flavonoids and the characterization of the extracts of ethyl acetate, ethyl alcohol and the coupling of the system through gas chromatography-mass spectrometry. Significant differences were found in the macro- and micromorphology, as well as in the secondary metabolite between the two varieties studied. The black mashua showed a higher concentration quantification of phenols and flavonoids. Some phytosterols and triterpenoids were reported for the first time in these species and the anti-inflammatory activity of the tubers was demonstrated. These findings can lead to further research for a future use in a clinical trial.
VL  - 6
IS  - 4
ER  -

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