World Journal of Medical Case Reports

Submit a Manuscript

Publishing with us to make your research visible to the widest possible audience.

Propose a Special Issue

Building a community of authors and readers to discuss the latest research and develop new ideas.

Bicytopenia and Urinary Infection Due to Chryseobacterium indologenes in an Immunocompetent Patient: A Case Report

Chryseobacterium indologenes was saprophytic gram-negative rods which can give multiple organ failure among the immunocompromised patients. In this paper, we herein report a case of bicytopenia and severe urinary infection due to Chryseobacterium indologenes in immunocompetent patient. The case consisted of a 45-year-old Malagasy male immunocompetent patient, admitted for acute onset of fever and chills three days after laparotomy. He had no past medical history. Clinical examination showed low blood pressure 80/40mmHg, heart rate beat 130 bpm. He presented distended bladder. The remainder of the physical examination was unremarkable. Laboratory test showed anemia and thrombocytopenia and elevated C reactive protein. Urine culture was positive for multiresistant C. indologenes, but the antibiogram was unavailable. The patient’s inflammatory and vasculitis work-up was unremarkable. Malignancy work-up was also negative. Bladder catheter was removed. Clinical improvement was observed on empiric levofloxacin® and trimethoprim-sulfamethoxazole® antibiotic therapy. Bicytopenia and severe form urinary infection in an immunocompetent patient was a manifestation of C. indologenes in our case. Association of broad-spectrum antibiotic might be used in nosocomial infection if the antibiogram was unavailable in this infection. Removing the bladder catheter may also be an important consideration. Furthermore, there was no similar case in our hospital. So, more epidemiological studies are required to explain the transmission mechanism and develop effective preventive measures.

Chryseobacterium indologenes, Nosocomial Urinary Infection, Bicytopenia, Immunocompetent

APA Style

Randriamampianina Tahianasoa, Ernestho-Ghoud Indretsy Mahavivola, Rakotonaivo Andoniaina, Soilihi Moustafa Abdou, Raveloson Nasolotsiry Enintsoa, et al. (2023). Bicytopenia and Urinary Infection Due to Chryseobacterium indologenes in an Immunocompetent Patient: A Case Report. World Journal of Medical Case Reports, 4(2), 22-25. https://doi.org/10.11648/j.wjmcr.20230402.11

ACS Style

Randriamampianina Tahianasoa; Ernestho-Ghoud Indretsy Mahavivola; Rakotonaivo Andoniaina; Soilihi Moustafa Abdou; Raveloson Nasolotsiry Enintsoa, et al. Bicytopenia and Urinary Infection Due to Chryseobacterium indologenes in an Immunocompetent Patient: A Case Report. World J. Med. Case Rep. 2023, 4(2), 22-25. doi: 10.11648/j.wjmcr.20230402.11

AMA Style

Randriamampianina Tahianasoa, Ernestho-Ghoud Indretsy Mahavivola, Rakotonaivo Andoniaina, Soilihi Moustafa Abdou, Raveloson Nasolotsiry Enintsoa, et al. Bicytopenia and Urinary Infection Due to Chryseobacterium indologenes in an Immunocompetent Patient: A Case Report. World J Med Case Rep. 2023;4(2):22-25. doi: 10.11648/j.wjmcr.20230402.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Acosta-Ochoa MI, Rodrigo-Parra A, Rodriguez-Martin F, Molina-Miguel A. Urinary infection due to Chryseobacterium indologenes. Nefrologia. 2013; 33: 620.
2. Omar A, Camara M, Fall S, Ngom-Cisse S, Fall B, Ba-Diallo A et al. Chryseobacterium indologenes in a woman with acute leukemia in Senegal: a case report. J Med Case Rep. 2014; 8: 138.
3. Palewar MS, Mudshingkar SS, Dohe V, Bharadwaj R. Infection by multidrug-resistant Chryseobacterium indologenes in cases of obstructive uropathy: Case series with short review. Med J DY Patil Univ. 2017; 10: 376-380.
4. Bhuyar G, Jain S, Shah H, Mehta VK. Urinary tract infection by Chryseobacterium indologenes. Indian J Med Microbiol. 2012; 30: 370-372.
5. Solanke V, Verma S, Nataraj G, Mehta P. Chryseobacterium indologenes associated urinary tract infection- a case report. Br Biomed Bull. 2015; 3: 75-80.
6. Mukerji R, Kakarala R, Smith SJ, Kusz GH. Chryseobacterium indologenes: an emerging infection in the USA. BMJ Case Rep 2016: 1-4.
7. Cunha V, Ferreira M, Fonseca AG, Diogo J. Community-acquired Chryseobacterium indologenes in an immunocompetent patient. JMM Case Reports 2014: 1.
8. Chen FL, Wang GC, Teng SO, Ou TY, Yu FL, Lee WS. Clinical and epidemiological features of Chryseobacterium indologenes infections: analysis of 215 cases. J Microbiol Immunol Infect. 2013; 46: 425-432.
9. Kirby JT, Sader HS, Walsh TR, Jones RN. Antimicrobial susceptibility and epidemiology of a worldwide collection of Chryseobacterium spp: Report from the SENTRY Antimicrobial Surveillance Program (1997-2001). J Clin Microbiol 2004; 42: 445-448.
10. Chou DW, Wu SL, Lee CT, Tai FT, Yu WL. Clinical characteristics, antimicrobial susceptibilities, and outcomes of patients with Chryseobacterium indologenes bacteremia in an intensive care unit. Jpn J Infect Dis. 2011; 64: 520-24.
11. Yadav VS, Das BK, Gautam H, Sood S, Kapil A, Mohapatra S. Chryseobacterium Indologenes: An emerging uropathogen among hematological malignancy patients. South Asian J Cancer. 2018; 7: 218.
12. Hsueh PR, Teng LJ, Ho SW et al.. Clinical and microbiological characteristics of Flavobacterium indologenes infections associated with indwelling devices. J Clin Microbiol 1996; 34: 1908-1913.
13. Wang YC, Yeh KM, Chiu SK et al.. Chryseobacterium indologenes peritonitis in a patient with malignant ascites. Int Med Case Rep J 2011; 4: 13-15.
14. Lin JT, Wang WS, Yen CC et al. Chryseobacterium indologenes bacteremia in a bone marrow transplant recipient with chronic graft-versus-host disease. Scand J Infect Dis 2003; 35: 882-883.
15. Mutcali SI, Yemisen M, Soylu H et al. Recurrent port infection due to chryseobacterium indologenes. Eurasian J Med 2013; 45: 60-61.