Augmentation Potency of Ethanol Seed Extract of <i>Ricinodendron heudelotii</i> on Some Male Reproductive Hormones in Wistar Albino Rats

Tamuno-boma Odinga; Ndidi Nwachoko; Christine Umanu Gabriel-Brisibe

doi:doi:10.11648/j.ijpc.20200602.11

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Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats

Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe

Published in International Journal of Pharmacy and Chemistry (Volume 6, Issue 2)

Received: 27 April 2020 Accepted: 20 May 2020 Published: 9 June 2020

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Abstract

The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.

Published in	International Journal of Pharmacy and Chemistry (Volume 6, Issue 2)
DOI	10.11648/j.ijpc.20200602.11
Page(s)	11-15
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Ricinodendron heudelotii, Testosterone, Follicle Stimulating Hormone, Luteinizing Hormone

References

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APA Style

Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. (2020). Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. International Journal of Pharmacy and Chemistry, 6(2), 11-15. https://doi.org/10.11648/j.ijpc.20200602.11

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ACS Style

Tamuno-boma Odinga; Ndidi Nwachoko; Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int. J. Pharm. Chem. 2020, 6(2), 11-15. doi: 10.11648/j.ijpc.20200602.11

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AMA Style

Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int J Pharm Chem. 2020;6(2):11-15. doi: 10.11648/j.ijpc.20200602.11

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@article{10.11648/j.ijpc.20200602.11,
  author = {Tamuno-boma Odinga and Ndidi Nwachoko and Christine Umanu Gabriel-Brisibe},
  title = {Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {6},
  number = {2},
  pages = {11-15},
  doi = {10.11648/j.ijpc.20200602.11},
  url = {https://doi.org/10.11648/j.ijpc.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20200602.11},
  abstract = {The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.},
 year = {2020}
}

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TY - JOUR
T1 - Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats
AU - Tamuno-boma Odinga
AU - Ndidi Nwachoko
AU - Christine Umanu Gabriel-Brisibe
Y1 - 2020/06/09
PY - 2020
N1 - https://doi.org/10.11648/j.ijpc.20200602.11
DO - 10.11648/j.ijpc.20200602.11
T2 - International Journal of Pharmacy and Chemistry
JF - International Journal of Pharmacy and Chemistry
JO - International Journal of Pharmacy and Chemistry
SP - 11
EP - 15
PB - Science Publishing Group
SN - 2575-5749
UR - https://doi.org/10.11648/j.ijpc.20200602.11
AB - The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.
VL - 6
IS - 2
ER -

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Author Information

Tamuno-boma Odinga

Department of Biochemistry, Faculty of Science, Rivers State University, Port Harcourt, Nigeria
Ndidi Nwachoko

Department of Biochemistry, Faculty of Science, Rivers State University, Port Harcourt, Nigeria
Christine Umanu Gabriel-Brisibe

Department of Medical Biochemistry, College of Medical Sciences, Rivers State University, Port Harcourt, Nigeria

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APA Style

Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. (2020). Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. International Journal of Pharmacy and Chemistry, 6(2), 11-15. https://doi.org/10.11648/j.ijpc.20200602.11

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ACS Style

Tamuno-boma Odinga; Ndidi Nwachoko; Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int. J. Pharm. Chem. 2020, 6(2), 11-15. doi: 10.11648/j.ijpc.20200602.11

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AMA Style

Tamuno-boma Odinga, Ndidi Nwachoko, Christine Umanu Gabriel-Brisibe. Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats. Int J Pharm Chem. 2020;6(2):11-15. doi: 10.11648/j.ijpc.20200602.11

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@article{10.11648/j.ijpc.20200602.11,
  author = {Tamuno-boma Odinga and Ndidi Nwachoko and Christine Umanu Gabriel-Brisibe},
  title = {Augmentation Potency of Ethanol Seed Extract of Ricinodendron heudelotii on Some Male Reproductive Hormones in Wistar Albino Rats},
  journal = {International Journal of Pharmacy and Chemistry},
  volume = {6},
  number = {2},
  pages = {11-15},
  doi = {10.11648/j.ijpc.20200602.11},
  url = {https://doi.org/10.11648/j.ijpc.20200602.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20200602.11},
  abstract = {The quest for the use of plants in the management of reproductive hormone dysfunction prompted this research. This study explored the effects of Ricinodendron heudelotti seed ethanol extract on some male reproductive hormones. Twenty five male albino rats were used. The animals were grouped into five and each group had five (5) albino rats. The extract was processed from the seeds of Ricinodendron heudelotti. Group A served as control, group B animals were administered with 300mg/kg.bw, while groups C, D and E animals were administered 450, 600 and 750 mg/kg.bw of the extract respectively for twenty one days. The animals were sacrificed and their blood samples were collected for the assay of testosterone, Follicle stimulating hormone (FSH) and Luteinizing hormone (LH). From the results obtained, the serum testosterone level of the experimental animals showed a concentration dependent increase in all the extract administered groups when compared with the value of the control group. FSH and LH levels showed an increase statistically (p≤0.05) in comparison to the level of the control. Ricinodendron heudelotti seed extract effectively increased the reproductive hormones of the animals by increasing the serum Testosterone, FSH and LH levels, hence suggests its effectiveness in enhancement of the male reproductive function.},
 year = {2020}
}

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