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Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report)

Received: 23 November 2021     Accepted: 6 December 2021     Published: 8 January 2022
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Abstract

Background to discuss the clinical characteristics of primary hyperparathyroidism (PHPT) with renal stones. Methods Clinical data of 13 Patients diagnosed With Primary hyperparathyroidism with repeated renal stones during May. 2006 to Oct. 2019 were analyzed retros Pectively. Results 13 patients, 4 males, 9 females, 7 kidney stones, 3 ureteral stones, 3 kidney and ureteral stones, 7 unilateral stones, 6 bilateral stones, 7 cases of rapid postoperative recurrence of kidney and ureteral stones were diagnosed with PHPT, 6 cases of preoperative diagnosis with pHPT; in all cases, blood calcium and parathyroid glandular hormone were significantly increased, 6 cases of blood phosphorus were decreased; 12 cases were diagnosed with thyroid ultrasound and neck CT, and the operation was performed One case was diagnosed as hyperparathyroidism by 99mTc-MIBI. Conclusions Parathyroidectomy is effective to treat the disease which can reduce recurrence of kidney stones remarkably. Early diagnosis and treatment of Primary hyperparathyroidism is helpful to reduce stone recurrence and Preserve renal function.

Published in International Journal of Clinical Urology (Volume 6, Issue 1)
DOI 10.11648/j.ijcu.20220601.11
Page(s) 1-4
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Primary Hyperparathyroidism, Renal Stone, Minimally Invasive Treatment

References
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[2] Fu Lijun, Yan Hongyin, Dong Hanhua, et al. Analysis of diagnosis and treatment of primary hyperparathyroidism [J]. Chinese Journal of Endocrine Surgery, 2010, 4 (12): 396-398.
[3] Yu Junxia, Ouyang Zhaoqiang, Zhang Xia, et al. Parathyroid adenoma with primary hyperparathyroidism clinical characteristics and analysis of the causes of misdiagnosis [J]. Clinical misdiagnosis and mistreatment, 2016, 28 (11): 21-25.
[4] Han Enkun, Liu Zikuan, Zhu Liwei, et al. Analysis of 101 cases of primary hyperparathyroidism [J]. Chinese Journal of Practical Surgery, 1998, 18: 147-149.
[5] Wang Gang, Zhang Xiaochun, Pan Bainian, et al. Diagnosis and treatment of primary hyperparathyroidism with urinary tract stones [J]. Journal of Clinical Urology, 2005, 85 (9): 618-620.
[6] Luo Hua, Huang Qijun, Qiu Mingquan, et al. Experience in diagnosis and treatment of kidney stones with primary hyperparathyroidism [J]. Journal of Modern Urology, 2012, 17 (4): 390-391.
[7] Corbetta S, Baccarelli A, Aroldi A, et al. Risk factors associated to kidney stones in primary hyperparathyroidism. J Endocrinol Invest, 2005, 28: 122—128.
[8] Zhang Tao, Ding Yancai, Jiang Xu, et al. Minimally invasive percutaneous nephroscope holmium laser combined with pneumatic lithotripsy for the treatment of kidney and upper ureteral calculi (report of 1870 cases) [J]. Chinese Journal of Minimally Invasive Surgery, 2013, 13 (06): 513-515.
[9] Ding Yancai, Zhang Tao, Liu Li, et al. Comparison of the curative effect of 3 standard flexible ureteroscope holmium laser lithotripsy in the treatment of kidney stones [J]. Northwestern National Defense Medical Journal, 2016, 37 (4): 223-225.
[10] Srivastava A, Zaman W, Singh V, et al. Efficacy of extracorporeal shock wave lithotripsy for solitary lower calyceal stone: a statistical model [J]. BJU international, 2004, 93 (3): 364-368.
[11] Yang Bo, Hu Weiguo, Hu Hao, et al. Analysis and countermeasures of failure of retrograde intrarenal surgery to treat kidney stones [J]. Journal of Peking University (Medical Edition), 2014, 46 (05): 794-797.
[12] Abdelshehid C, Ahlering M T, Chou D, et al. Comparison of flexible ureteroscopes: deflection, irrigant flow and optical characteristics [J]. The Journal of urology, 2005, 173 (6): 2017-2021.
[13] Marchini G S, Batagello C A, Monga M, et al. In Vitro Evaluation of Single-Use Digital Flexible Ureteroscopes: A Practical Comparison for a Patient-Centered Approach [J]. J Endourol, 2018, 32 (3): 184-191.
[14] Yang Enguang, Jing Suoshi, Wang Zhiping. The application status and research progress of disposable flexible ureteroscope [J]. Chinese Journal of Minimally Invasive Surgery, 2019, 19 (09): 846-848.
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  • APA Style

    Li Feiyu, Xu Rui, Liu Li, Ding Yancai, Ma Xiao Yun. (2022). Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report). International Journal of Clinical Urology, 6(1), 1-4. https://doi.org/10.11648/j.ijcu.20220601.11

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    ACS Style

    Li Feiyu; Xu Rui; Liu Li; Ding Yancai; Ma Xiao Yun. Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report). Int. J. Clin. Urol. 2022, 6(1), 1-4. doi: 10.11648/j.ijcu.20220601.11

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    AMA Style

    Li Feiyu, Xu Rui, Liu Li, Ding Yancai, Ma Xiao Yun. Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report). Int J Clin Urol. 2022;6(1):1-4. doi: 10.11648/j.ijcu.20220601.11

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  • @article{10.11648/j.ijcu.20220601.11,
      author = {Li Feiyu and Xu Rui and Liu Li and Ding Yancai and Ma Xiao Yun},
      title = {Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report)},
      journal = {International Journal of Clinical Urology},
      volume = {6},
      number = {1},
      pages = {1-4},
      doi = {10.11648/j.ijcu.20220601.11},
      url = {https://doi.org/10.11648/j.ijcu.20220601.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.11},
      abstract = {Background to discuss the clinical characteristics of primary hyperparathyroidism (PHPT) with renal stones. Methods Clinical data of 13 Patients diagnosed With Primary hyperparathyroidism with repeated renal stones during May. 2006 to Oct. 2019 were analyzed retros Pectively. Results 13 patients, 4 males, 9 females, 7 kidney stones, 3 ureteral stones, 3 kidney and ureteral stones, 7 unilateral stones, 6 bilateral stones, 7 cases of rapid postoperative recurrence of kidney and ureteral stones were diagnosed with PHPT, 6 cases of preoperative diagnosis with pHPT; in all cases, blood calcium and parathyroid glandular hormone were significantly increased, 6 cases of blood phosphorus were decreased; 12 cases were diagnosed with thyroid ultrasound and neck CT, and the operation was performed One case was diagnosed as hyperparathyroidism by 99mTc-MIBI. Conclusions Parathyroidectomy is effective to treat the disease which can reduce recurrence of kidney stones remarkably. Early diagnosis and treatment of Primary hyperparathyroidism is helpful to reduce stone recurrence and Preserve renal function.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Diagnosis and Treatment of Primary Hyperparathyroidism with Repeated Bilateral Renal Stones (13 Cases Report)
    AU  - Li Feiyu
    AU  - Xu Rui
    AU  - Liu Li
    AU  - Ding Yancai
    AU  - Ma Xiao Yun
    Y1  - 2022/01/08
    PY  - 2022
    N1  - https://doi.org/10.11648/j.ijcu.20220601.11
    DO  - 10.11648/j.ijcu.20220601.11
    T2  - International Journal of Clinical Urology
    JF  - International Journal of Clinical Urology
    JO  - International Journal of Clinical Urology
    SP  - 1
    EP  - 4
    PB  - Science Publishing Group
    SN  - 2640-1355
    UR  - https://doi.org/10.11648/j.ijcu.20220601.11
    AB  - Background to discuss the clinical characteristics of primary hyperparathyroidism (PHPT) with renal stones. Methods Clinical data of 13 Patients diagnosed With Primary hyperparathyroidism with repeated renal stones during May. 2006 to Oct. 2019 were analyzed retros Pectively. Results 13 patients, 4 males, 9 females, 7 kidney stones, 3 ureteral stones, 3 kidney and ureteral stones, 7 unilateral stones, 6 bilateral stones, 7 cases of rapid postoperative recurrence of kidney and ureteral stones were diagnosed with PHPT, 6 cases of preoperative diagnosis with pHPT; in all cases, blood calcium and parathyroid glandular hormone were significantly increased, 6 cases of blood phosphorus were decreased; 12 cases were diagnosed with thyroid ultrasound and neck CT, and the operation was performed One case was diagnosed as hyperparathyroidism by 99mTc-MIBI. Conclusions Parathyroidectomy is effective to treat the disease which can reduce recurrence of kidney stones remarkably. Early diagnosis and treatment of Primary hyperparathyroidism is helpful to reduce stone recurrence and Preserve renal function.
    VL  - 6
    IS  - 1
    ER  - 

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Author Information
  • Department of Urology, the 942 Hospital of PLA, Yinchuan, China

  • Department of Laser, General Hospital of Ningxia Medical University, Yinchuan, China

  • Department of Urology, the 942 Hospital of PLA, Yinchuan, China

  • Department of Urology, the 942 Hospital of PLA, Yinchuan, China

  • Department of Urology, the 942 Hospital of PLA, Yinchuan, China

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