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Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values

Received: 28 August 2026     Accepted: 20 September 2026     Published: 29 October 2026
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Abstract

Serum biochemical parameters provide valuable information on the physiological, metabolic, and health status of animals and are commonly used in veterinary clinical practice. However, biochemical values vary with breed, nutrition, management, environmental conditions, age, sex, and physiological status, highlighting the need for locally relevant data. This study examined serum biochemical parameters of goats in Sokoto Metropolis, to produce preliminary local biochemical values for clinical assessment. Forty (40) apparently healthy goats were randomly selected from households, farms, and semi-intensive production systems. Approximately 5 mL of blood was collected from the jugular vein into plain tubes, and serum was analyzed using an automated chemistry analyzer at the Clinical Pathology Laboratory. Total protein, albumin, globulin, ALT, AST, ALP, urea, creatinine, total bilirubin, and direct bilirubin were Parameters assessed. The data were summarized using descriptive statistics. Mean ± SD values were 8.28 ± 1.02 g/dL for total protein, 2.61 ± 0.23 g/dL for albumin, 5.67 ± 1.05 g/dL for globulin, 40.89 ± 71.10 U/L for ALT, 32.23 ± 36.84 U/L for AST, 99.49 ± 78.65 U/L for ALP, 47.64 ± 24.87 mg/dL for urea, 4.35 ± 0.53 mg/dL for creatinine, 3.84 ± 4.02 mg/dL for total bilirubin, and 6.52 ± 1.56 mg/dL for direct bilirubin. Most values were mostly comparable with previous reports for indigenous Nigerian goats, even though considerable variation occurred in some liver enzymes and bilirubin indices. These findings provide preliminary local biochemical data and emphasize the importance of regional, nutritional, environmental, and management factors in interpreting serum biochemical results.

Published in Biochemistry and Molecular Biology (Volume 11, Issue 3)
DOI 10.11648/j.bmb.20261103.12
Page(s) 59-64
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2026. Published by Science Publishing Group

Keywords

Liver Function, Renal Function, Red Sokoto Goat, Sokoto

References
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[2] Daramola, J. O., Adeloye, A. A., Fatoba, T. A., & Soladoye, A. O. (2005). Haematological and biochemical parameters of West African Dwarf goats. Livestock Research for Rural Development, 17(8), 95-102.
[3] Njidda, A. A., Hassan, I. T., & Olatunji, E. A. (2013). Haematological and biochemical parameters of goats of semi-arid environment fed on natural grazing rangeland of Northern Nigeria. IOSR Journal of Agriculture and Veterinary Science, 3(2), 1-8.
[4] Aba, P. E., Oguike, M. A., & Omede, A. A. (2020). Serum biochemical profiles of Red Sokoto goats raised under different management systems in Southeastern Nigeria. Nigerian Veterinary Journal, 41(3), 150-159.
[5] Kolo, P. S., Lawal, M., & Ibrahim, S. (2021). Comparative evaluation of serum enzyme activities in Red Sokoto and Sahel goats managed under semi-intensive systems in Northwestern Nigeria. Nigerian Journal of Animal Science, 23(2), 87-96.
[6] Ameh, J. A., & Egwu, G. O. (2020). Livestock development in the arid and semi-arid zones of Nigeria: Challenges and opportunities. Nigerian Veterinary Journal, 41(1), 88-97.
[7] Waba, J. T., Malgwi, I. H., & Abubakar, M. M. (2023). Assessment of serum biochemical parameters as indicators of liver function in indigenous goat breeds in Northern Nigeria. Tropical Animal Health and Production, 55(4), 203-214.
[8] Afolabi, K. D., Akinsoyinu, A. O., & Mba, A. U. (2021). Nutritional and economic significance of goats in rural livelihoods in West Africa. Tropical Animal Health and Production, 53(6), 1-9.
[9] Ogunsanmi, A. O., Taiwo, V. O., & Oke, O. A. (2002). Biochemical, hematological and physical changes in West African Dwarf goats experimentally infected with Trypanosoma brucei. Israel Journal of Veterinary Medicine, 57(1), 1-9.
[10] Bukola, T. A., Olabisi, O. A., & Odetola, O. M. (2022). Assessment of liver enzyme activities and serum metabolites in goats reared under varying nutritional conditions. Sokoto Journal of Veterinary Sciences, 20(1), 33-41.
[11] Idamokoro, E. M., Muchenje, V., & Masika, P. J. (2017). Yield and milk composition at different stages of lactation from a small herd of Nguni, Boer, and non-descript goats raised in an extensive production system. Sustainability, 9(6), 1000.
[12] Aminu, H. O., & Adamu, M. (2021). Evaluation of reference values for serum biochemical parameters in Sahel goats reared in Northwestern Nigeria. Nigerian Journal of Animal Health and Production, 18(2), 77-86.
[13] Ayo, J. O., Obidi, J. A., & Rekwot, P. I. (2018). Seasonal variations in physiological responses and serum biochemical parameters of livestock under tropical conditions. African Journal of Biotechnology, 17(4), 101-110.
[14] Yakubu, A., Salako, A. E., & Imumorin, I. G. (2011). Comparative multivariate analysis of biometric traits of West African Dwarf and Red Sokoto goats. Tropical Animal Health and Production, 43, 561-566.
[15] Abubakar, M., Ibrahim, S., & Waba, J. T. (2021). Comparative assessment of biochemical indices in West African Dwarf and Red Sokoto goats in Northern Nigeria. Nigerian Journal of Animal Production, 48(2), 203-212.
[16] Al-Musawi, Z. J., Al-Khafaji, N. J., & Hussain, N. A. (2017). Serum biochemical responses of goats to heat stress and nutritional variation. Journal of Animal and Veterinary Advances, 16(2), 59-67.
[17] Adeniran, K. A., Olatunji, E. A., & Oladele, S. B. (2020). A review of small ruminant production in Nigeria: Potentials and challenges. Nigerian Journal of Animal Science, 22(3), 45-56.
[18] Tukur, H. M., Bello, M. B., & Lawal, M. (2014). The Red Sokoto goat: Its characteristics, management, and economic importance. Nigerian Journal of Animal Science, 16(2), 45-53.
[19] Oluwatayo, I. B., & Oluwatayo, T. B. (2018). Small ruminants as a source of financial security among women in rural southwest Nigeria. Journal of Agribusiness and Rural Development, 49(3), 333-341.
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    Jafaru, A. I., Ahmad, A. A., Durkwa, H. U., Pali, M. B., Dahiru, A., et al. (2026). Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values. Biochemistry and Molecular Biology, 11(3), 59-64. https://doi.org/10.11648/j.bmb.20261103.12

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    ACS Style

    Jafaru, A. I.; Ahmad, A. A.; Durkwa, H. U.; Pali, M. B.; Dahiru, A., et al. Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values. Biochem. Mol. Biol. 2026, 11(3), 59-64. doi: 10.11648/j.bmb.20261103.12

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    AMA Style

    Jafaru AI, Ahmad AA, Durkwa HU, Pali MB, Dahiru A, et al. Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values. Biochem Mol Biol. 2026;11(3):59-64. doi: 10.11648/j.bmb.20261103.12

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  • @article{10.11648/j.bmb.20261103.12,
      author = {Abdullahi Ishaq Jafaru and Abdulganiyyu Abdullahi Ahmad and Hussaini Usman Durkwa and Muazu Bala Pali and Ashiru Dahiru and Faruk Bilal Dabai and Sadiya Bello Usman and Mercy Christopher Danzaria and Nafisat Abdulazeez and Ibrahim Maina Hassan},
      title = {Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values},
      journal = {Biochemistry and Molecular Biology},
      volume = {11},
      number = {3},
      pages = {59-64},
      doi = {10.11648/j.bmb.20261103.12},
      url = {https://doi.org/10.11648/j.bmb.20261103.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bmb.20261103.12},
      abstract = {Serum biochemical parameters provide valuable information on the physiological, metabolic, and health status of animals and are commonly used in veterinary clinical practice. However, biochemical values vary with breed, nutrition, management, environmental conditions, age, sex, and physiological status, highlighting the need for locally relevant data. This study examined serum biochemical parameters of goats in Sokoto Metropolis, to produce preliminary local biochemical values for clinical assessment. Forty (40) apparently healthy goats were randomly selected from households, farms, and semi-intensive production systems. Approximately 5 mL of blood was collected from the jugular vein into plain tubes, and serum was analyzed using an automated chemistry analyzer at the Clinical Pathology Laboratory. Total protein, albumin, globulin, ALT, AST, ALP, urea, creatinine, total bilirubin, and direct bilirubin were Parameters assessed. The data were summarized using descriptive statistics. Mean ± SD values were 8.28 ± 1.02 g/dL for total protein, 2.61 ± 0.23 g/dL for albumin, 5.67 ± 1.05 g/dL for globulin, 40.89 ± 71.10 U/L for ALT, 32.23 ± 36.84 U/L for AST, 99.49 ± 78.65 U/L for ALP, 47.64 ± 24.87 mg/dL for urea, 4.35 ± 0.53 mg/dL for creatinine, 3.84 ± 4.02 mg/dL for total bilirubin, and 6.52 ± 1.56 mg/dL for direct bilirubin. Most values were mostly comparable with previous reports for indigenous Nigerian goats, even though considerable variation occurred in some liver enzymes and bilirubin indices. These findings provide preliminary local biochemical data and emphasize the importance of regional, nutritional, environmental, and management factors in interpreting serum biochemical results.},
     year = {2026}
    }
    

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  • TY  - JOUR
    T1  - Serum Biochemical Profiles of Apparently Healthy Goats in Sokoto Metropolis, Northwestern Nigeria: Preliminary Local Reference Values
    AU  - Abdullahi Ishaq Jafaru
    AU  - Abdulganiyyu Abdullahi Ahmad
    AU  - Hussaini Usman Durkwa
    AU  - Muazu Bala Pali
    AU  - Ashiru Dahiru
    AU  - Faruk Bilal Dabai
    AU  - Sadiya Bello Usman
    AU  - Mercy Christopher Danzaria
    AU  - Nafisat Abdulazeez
    AU  - Ibrahim Maina Hassan
    Y1  - 2026/10/29
    PY  - 2026
    N1  - https://doi.org/10.11648/j.bmb.20261103.12
    DO  - 10.11648/j.bmb.20261103.12
    T2  - Biochemistry and Molecular Biology
    JF  - Biochemistry and Molecular Biology
    JO  - Biochemistry and Molecular Biology
    SP  - 59
    EP  - 64
    PB  - Science Publishing Group
    SN  - 2575-5048
    UR  - https://doi.org/10.11648/j.bmb.20261103.12
    AB  - Serum biochemical parameters provide valuable information on the physiological, metabolic, and health status of animals and are commonly used in veterinary clinical practice. However, biochemical values vary with breed, nutrition, management, environmental conditions, age, sex, and physiological status, highlighting the need for locally relevant data. This study examined serum biochemical parameters of goats in Sokoto Metropolis, to produce preliminary local biochemical values for clinical assessment. Forty (40) apparently healthy goats were randomly selected from households, farms, and semi-intensive production systems. Approximately 5 mL of blood was collected from the jugular vein into plain tubes, and serum was analyzed using an automated chemistry analyzer at the Clinical Pathology Laboratory. Total protein, albumin, globulin, ALT, AST, ALP, urea, creatinine, total bilirubin, and direct bilirubin were Parameters assessed. The data were summarized using descriptive statistics. Mean ± SD values were 8.28 ± 1.02 g/dL for total protein, 2.61 ± 0.23 g/dL for albumin, 5.67 ± 1.05 g/dL for globulin, 40.89 ± 71.10 U/L for ALT, 32.23 ± 36.84 U/L for AST, 99.49 ± 78.65 U/L for ALP, 47.64 ± 24.87 mg/dL for urea, 4.35 ± 0.53 mg/dL for creatinine, 3.84 ± 4.02 mg/dL for total bilirubin, and 6.52 ± 1.56 mg/dL for direct bilirubin. Most values were mostly comparable with previous reports for indigenous Nigerian goats, even though considerable variation occurred in some liver enzymes and bilirubin indices. These findings provide preliminary local biochemical data and emphasize the importance of regional, nutritional, environmental, and management factors in interpreting serum biochemical results.
    VL  - 11
    IS  - 3
    ER  - 

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Author Information
  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Federal University of Agriculture, Zuru, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Abubakar Tafawa Balewa University, Bauchi, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Abubakar Tafawa Balewa University, Bauchi, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Abubakar Tafawa Balewa University, Bauchi, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

  • Department of Veterinary Physiology and Biochemistry, Usmanu Danfodiyo University, Sokoto, Nigeria

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