Metals contribute important roles in biological system. It is recognized that metals are highly linked in cellular and subcellular functions. With the application of novel and experienced tools to study biological and biochemical systems the true role of inorganic salts in biological systems can be studied. Schiff base metal complexes show a broad range of biological activity. The activity of Schiff base ligand is usually increased by complexation with the metal ion. The copper complexes of Schiff bases have striking properties such as antibacterial, antifungal, antiviral, anti-inflammatory, anti-tumor and cytotoxic activities, plant development controller, enzymatic activity and applications in pharmaceutical fields. The divalent cations Zn2+, Ca2+ and Mg2+ prevent cytotoxicity and in vivo antagonize Cd- induced carcinogenesis. Lack of body iron is common in cancer patients and it is associated with complications in surgery and in animal experiments. The transport of iron and other metal ions by the blood plasma is achieved through the formation of protein complexes. Copper is placed as a vital metalloelement and is primarily connected with copper-dependent cellular enzymes. Metals are also used as inorganic drugs for many diseases. In this review our main focused on research undertaken for biological activity study of Cu(II) metal complexes containing Schiff bases over the past few decades.
| Published in | American Journal of Heterocyclic Chemistry (Volume 5, Issue 1) |
| DOI | 10.11648/j.ajhc.20190501.14 |
| Page(s) | 11-22 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Schiff Bases, Biological Activity, Copper Complexes, Antibacterial, Antifungal, Antiviral, Anti-inflammatory, Anti-tumor and Cytotoxic Activity
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APA Style
Md. Nur Amin Bitu, Md. Saddam Hossain, A. A. S. M. Zahid, C. M. Zakaria, Md. Kudrat-E-Zahan. (2019). Anti-pathogenic Activity of Cu(II) Complexes Incorporating Schiff Bases: A Short Review. American Journal of Heterocyclic Chemistry, 5(1), 11-22. https://doi.org/10.11648/j.ajhc.20190501.14
ACS Style
Md. Nur Amin Bitu; Md. Saddam Hossain; A. A. S. M. Zahid; C. M. Zakaria; Md. Kudrat-E-Zahan. Anti-pathogenic Activity of Cu(II) Complexes Incorporating Schiff Bases: A Short Review. Am. J. Heterocycl. Chem. 2019, 5(1), 11-22. doi: 10.11648/j.ajhc.20190501.14
AMA Style
Md. Nur Amin Bitu, Md. Saddam Hossain, A. A. S. M. Zahid, C. M. Zakaria, Md. Kudrat-E-Zahan. Anti-pathogenic Activity of Cu(II) Complexes Incorporating Schiff Bases: A Short Review. Am J Heterocycl Chem. 2019;5(1):11-22. doi: 10.11648/j.ajhc.20190501.14
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Download@article{10.11648/j.ajhc.20190501.14,
author = {Md. Nur Amin Bitu and Md. Saddam Hossain and A. A. S. M. Zahid and C. M. Zakaria and Md. Kudrat-E-Zahan},
title = {Anti-pathogenic Activity of Cu(II) Complexes Incorporating Schiff Bases: A Short Review},
journal = {American Journal of Heterocyclic Chemistry},
volume = {5},
number = {1},
pages = {11-22},
doi = {10.11648/j.ajhc.20190501.14},
url = {https://doi.org/10.11648/j.ajhc.20190501.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhc.20190501.14},
abstract = {Metals contribute important roles in biological system. It is recognized that metals are highly linked in cellular and subcellular functions. With the application of novel and experienced tools to study biological and biochemical systems the true role of inorganic salts in biological systems can be studied. Schiff base metal complexes show a broad range of biological activity. The activity of Schiff base ligand is usually increased by complexation with the metal ion. The copper complexes of Schiff bases have striking properties such as antibacterial, antifungal, antiviral, anti-inflammatory, anti-tumor and cytotoxic activities, plant development controller, enzymatic activity and applications in pharmaceutical fields. The divalent cations Zn2+, Ca2+ and Mg2+ prevent cytotoxicity and in vivo antagonize Cd- induced carcinogenesis. Lack of body iron is common in cancer patients and it is associated with complications in surgery and in animal experiments. The transport of iron and other metal ions by the blood plasma is achieved through the formation of protein complexes. Copper is placed as a vital metalloelement and is primarily connected with copper-dependent cellular enzymes. Metals are also used as inorganic drugs for many diseases. In this review our main focused on research undertaken for biological activity study of Cu(II) metal complexes containing Schiff bases over the past few decades.},
year = {2019}
}
TY - JOUR T1 - Anti-pathogenic Activity of Cu(II) Complexes Incorporating Schiff Bases: A Short Review AU - Md. Nur Amin Bitu AU - Md. Saddam Hossain AU - A. A. S. M. Zahid AU - C. M. Zakaria AU - Md. Kudrat-E-Zahan Y1 - 2019/04/22 PY - 2019 N1 - https://doi.org/10.11648/j.ajhc.20190501.14 DO - 10.11648/j.ajhc.20190501.14 T2 - American Journal of Heterocyclic Chemistry JF - American Journal of Heterocyclic Chemistry JO - American Journal of Heterocyclic Chemistry SP - 11 EP - 22 PB - Science Publishing Group SN - 2575-5722 UR - https://doi.org/10.11648/j.ajhc.20190501.14 AB - Metals contribute important roles in biological system. It is recognized that metals are highly linked in cellular and subcellular functions. With the application of novel and experienced tools to study biological and biochemical systems the true role of inorganic salts in biological systems can be studied. Schiff base metal complexes show a broad range of biological activity. The activity of Schiff base ligand is usually increased by complexation with the metal ion. The copper complexes of Schiff bases have striking properties such as antibacterial, antifungal, antiviral, anti-inflammatory, anti-tumor and cytotoxic activities, plant development controller, enzymatic activity and applications in pharmaceutical fields. The divalent cations Zn2+, Ca2+ and Mg2+ prevent cytotoxicity and in vivo antagonize Cd- induced carcinogenesis. Lack of body iron is common in cancer patients and it is associated with complications in surgery and in animal experiments. The transport of iron and other metal ions by the blood plasma is achieved through the formation of protein complexes. Copper is placed as a vital metalloelement and is primarily connected with copper-dependent cellular enzymes. Metals are also used as inorganic drugs for many diseases. In this review our main focused on research undertaken for biological activity study of Cu(II) metal complexes containing Schiff bases over the past few decades. VL - 5 IS - 1 ER -
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