International Journal of Otorhinolaryngology


Submit a Manuscript

Publishing with us to make your research visible to the widest possible audience.

Propose a Special Issue

Building a community of authors and readers to discuss the latest research and develop new ideas.

Research Article |

Endovascular Management of Massive Bleeding from Laryngeal Tumor

Laryngeal tumors are commonly seen in Ear, Nose and Throat (ENT) department. Hemoptysis is one of the common presentations of these tumors. Carotid blowout syndrome (CBS) due to bleeding from the pseudo-aneurysm (PA) is a dreaded complication of head and neck tumors. Sometimes it can be massive and difficult to control and maybe fatal. Surgical bypass or ligation of external carotid was the only option available, but it had high mortality and morbidity associated with it. Endovascular management has given a new hope for these patients, in the form of covered stent implantation. These endovascular stents works by reconstructing the arterial wall, maintain its patency and decrease the ischemic complication rate which was higher with surgical option due to vessel deconstruction strategies. Recurrent bleeding can occur due to infection of stent which is a fearful complication but it occurs late and its reported rate in the previous studies ranges from 33-86%. We present a case of such tumor complicated with massive bleeding, which was managed by an endovascular approach. This is probably the first case where massive bleeding from the laryngeal tumor was managed with endovascular stent and embolization of blood vessels supplying the larynx.

Laryngeal Tumor, Bleeding, Embolization

APA Style

Bharadwaj, R., Datta, G., Pruthi, T., Mittal, S. (2023). Endovascular Management of Massive Bleeding from Laryngeal Tumor. International Journal of Otorhinolaryngology, 9(2), 26-29.

ACS Style

Bharadwaj, R.; Datta, G.; Pruthi, T.; Mittal, S. Endovascular Management of Massive Bleeding from Laryngeal Tumor. Int. J. Otorhinolaryngol. 2023, 9(2), 26-29. doi: 10.11648/j.ijo.20230902.13

AMA Style

Bharadwaj R, Datta G, Pruthi T, Mittal S. Endovascular Management of Massive Bleeding from Laryngeal Tumor. Int J Otorhinolaryngol. 2023;9(2):26-29. doi: 10.11648/j.ijo.20230902.13

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Bernier J, Cooper JS, Pajak TF, van Glabbeke M, Bourhis J, Forastiere A, et al. Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501) Head Neck. 2005; 27: 843–50.
2. Barnes L, Eveson JW, Reichart P, Sidransky D. World Health Organization Classification of Tumours: Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005.
3. Canova C, Richiardi L, Merletti F, Pentenero M, Gervasio C, Tanturri G, et al. Alcohol, tobacco and genetic susceptibility In relation to cancers of the upper aerodigestive tract in northern Italy. Tumori. 2010; 96: 1–10.
4. Steuer CE, El-Deiry M, Parks JR, Higgins KA, Saba NF. An an update on larynx cancer. CA: A Cancer Journal for Clinicians. 2017; 67 (1): 31-50.
5. Remmelts AJ, Hoebers FJP, Klop WMC, Balm AJM, Hamming-Vrieze O, van den Brekel MWM. Evaluation of laser surgery and radiotherapy as treatment modalities in early stage laryngeal carcinoma: tumour outcome and quality of voice. Eur Arch Otorhinolaryngol. 2013; 270 (7): 2079-2087.
6. Pereira J, Phan T. Management of bleeding in patients with advanced cancer. Oncologist. 2004; 9 (5): 561-570.
7. Johnstone C, Rich SE. Bleeding in cancer patients and its treatment: a review. Ann Palliat Med. 2018; 7 (2): 265-273.
8. Soria JC, Deutsch E. Hemorrhage caused by antiangiogenic therapy within previously irradiated areas: expected consequence of tumor shrinkage or a warning for antiangiogenic agents combined to radiotherapy? Ann Oncol. 2011; 22 (6): 1247-1249.
9. Weycker D, Hatfield M, Grossman A, et al. Risk and consequences of chemotherapy-induced thrombocytopenia in US clinical practice. BMC Cancer. 2019; 19 (1): 151.
10. Rosenthal DI, Mohamed AS, Weber RS, et al. Long-term outcomes after surgical or nonsurgical initial therapy for patients with T4 squamous cell carcinoma of the larynx: a 3-decade survey. Cancer. 2015; 121 (10): 1608- 1619.
11. Sadoughi B. Quality of life after conservation surgery for laryngeal cancer. Otolaryngol Clin North Am. 2015; 48 (4): 655- 665.
12. Shuman AG, Larkin K, Thomas D, et al. Patient reflections on decision making for laryngeal cancer treatment. Otolaryngol Head Neck Surg. 2017; 156 (2): 299- 304.
13. Lotempio MM, Wang KH, Sadeghi A, Delacure MD, Juillard GF, Wang MB. Comparison of quality of life outcomes in laryngeal cancer patients following chemoradiation vs. total laryngectomy. Otolaryngol Head Neck Surg. 2005; 132 (6): 948- 953.
14. Hamilton DW, Bins JE, McMeekin P, et al. Quality compared to quantity of life in laryngeal cancer: a time trade-off study. Head Neck. 2016; 38 (S1): E631- E637.
15. Citardi MJ, Chaloupka JC, Son YH et al. Management of carotid artery rupture by monitored endovascular therapeutic occlusion (1988–1994). Laryngoscope 1995; 105: 1086–92.
16. Lesley WS, Chaloupka JC, Weigele JB, et al.. Preliminary experience with endovascular reconstruction for the management of carotid blowout syndrome. AJNR Am J Neuroradiol 2003; 24: 975–81.