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Diagnosis and Control of Peste Des Petits (PPR) in Small Ruminants: A Comprehensive Review

PPR (Peste des petits ruminants) is a highly infectious serious infection that affects a lot of sheep and goats. In nations like Pakistan, where small ruminant products are crucial for long-term livelihoods, the infection has a significant economic impact. Goats are known to be more sensitive to the sickness than other animals. It's a highly contagious illness that affects tiny ruminants and has a high morbidity and fatality rate. The timing of infection, the spread of the virus, and the early identification of the disease all need to be better understood. Disease has an almost universal geographic spread. The PPRV is a virus that affects both domestic and wild ruminants. In Pakistan, PPR is diagnosed mostly by postmortem examination of clinical symptoms and lesions. Conjunctivitis and rhinotracheitis, stomatitis, gastroenteritis, and pneumonia are all caused by PPRV, a lymphotropic and epitheliotropic virus. Pathognomonic symptoms include necrotizing tonsils, fibrinohemorrhagic enteritis, proliferative interstitial pneumonia, supportiv bronchointerstitial pneumonia, multinucleated giant cells [syncytia], and cytoplasmic and/or nuclear eosinophilic inclusion bodies. The acute type, which is identical to rinderpest, is most commonly found in goats. A severe respiratory condition is a common symptom of PPR. The subacute type is more common in sheep, although it can also happen in goats. Immunization, isolation, transportation restriction, and hygienic slaughter and disinfection are all part of the control and preventive programme. Moreover, in addition to the issue of resistance to antibiotics, further research into antibiotics resistance and the development of new antibiotics can aid in enhanced therapeutic intervention. Reviewing existing preventative approaches and focusing on creating new strain-based or recombinant vaccines that target specific antigens is the most effective strategy to treat the illness internationally (capsular or cellular).

Peste Des Petit Ruminants, Morbillivirus, Epidemic Curve, Small Ruminants, Diagnosis, Control

APA Style

Adnan Yousaf, Dad Muhammad Anwar, Mehtab Ahmed, Imran Qaiser, Rasheed Ahmed Rabbani, et al. (2023). Diagnosis and Control of Peste Des Petits (PPR) in Small Ruminants: A Comprehensive Review . Animal and Veterinary Sciences, 11(5), 111-127. https://doi.org/10.11648/j.avs.20231105.13

ACS Style

Adnan Yousaf; Dad Muhammad Anwar; Mehtab Ahmed; Imran Qaiser; Rasheed Ahmed Rabbani, et al. Diagnosis and Control of Peste Des Petits (PPR) in Small Ruminants: A Comprehensive Review . Anim. Vet. Sci. 2023, 11(5), 111-127. doi: 10.11648/j.avs.20231105.13

AMA Style

Adnan Yousaf, Dad Muhammad Anwar, Mehtab Ahmed, Imran Qaiser, Rasheed Ahmed Rabbani, et al. Diagnosis and Control of Peste Des Petits (PPR) in Small Ruminants: A Comprehensive Review . Anim Vet Sci. 2023;11(5):111-127. doi: 10.11648/j.avs.20231105.13

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Atmaca HT, Kul O (2012) Examination of epithelial tissue cytokine response to natural peste des petits ruminants virus (PPRV) infection in sheep and goats by immunohistochemistry. Histol Histopathol 27: 69-78.
2. Balamurugan V, Sen A, Saravanan P, Singh RP, Singh RK (2006) One-step multiplex RT-PCR assay for the detection of Peste-des-petits ruminants virus in clinical samples. Vet Res Commun 30: 655-666.
3. Abbas F, Ullah A, Awan MA, Tariq MM, Ali M, Khan FA (2012) Tissue Culture Based Peste Des Petits Ruminants (PPR) Vaccine at CASVAB, Quetta, Pakistan. Pak. j. life soc. Pak J life Soc Sci. 10 (1): 80–3.
4. Abraham G, Berhan A (2001). The use of antigen-capture enzyme-linked immunosorbent assay (ELISA) for the diagnosis of rinderpest and peste des petits ruminants in Ethiopia. Trop Anim Health Product. 33: 423–30. doi: 10.1023/A:1010547907730.
5. Abraham G, Sintayehu A, Libeau G, Albina E, Roger F (2005) Antibody seroprevalences against peste des petits ruminants (PPR) virus in camels, cattle, goats and sheep in Ethiopia. Pre Vet Med 70: 51-57.
6. Abubakar AB, El-Yuduga AD, Baba SS (2008) Seroprevalence of Morbillivirus antibody and abattoir survey of one humped slaughtered camels (Camelus dromedarius) in Maiduguri municipal abattoir, Maiduguri, Nigeria. Asian Journal Scientail Research 1: 85-89.
7. Abubakar M, Ali Q, Khan HA (2008) Prevalence and mortality rate of peste des petits ruminant (PPR): possible association with abortion in goat. Trop Anim Health Pro 40: 317-321.
8. Abubakar M, Arshed MJ, Zahur AB, Ali Q, Banyard AC. (2012) Natural infection with peste des petits ruminants virus: A pre and post vaccinal assessment following an outbreak scenario. Virus Res. 167: 43–7.
9. Abubakar M, Arshed MJ, Zahur AB, Ullah F, Ishfaq F, Ali Q. (2011) Post Outbreak Profile of Peste des petits ruminants (PPR) Virus Antibodies in Relation with Vaccination in Recovered Goats. Pak J Life Soc Sci. 9 (2): 169–71.
10. Abubakar M, Jamal SM, Arshed MJ, Hussain M, Ali Q. (2009) Peste des petits ruminants virus (PPRV) infection; Its association with species, seasonal variations and geography. Trop Anim Health Prod. 41: 1197–202.
11. Abubakar M, Jamal SM, Hussain M, Ali Q (2008) Incidence of peste des petits ruminants (PPR) virus in sheep and goat as detected by immuno-capture ELISA (Ic ELISA). Small Ruminant Res. 75: 256–9.
12. Abubakar M, Jamal SM, Khan MA, Ali Q (2008) Peste des petits ruminants outbreak in small ruminants of Northern areas of Pakistan. Res J Vete Sci. 1 (1): 56–61.
13. Abubakar M, Manzoor S, Ali Q (2015) Evaluating the role of vaccine to combat peste des petits ruminants outbreaks in endemic disease situation. J Anim Sci Technol. 57: 2.
14. Abubakar M, Munir M (2014). Peste des Petits Ruminants Virus: An Emerging Threat to Goat Farming in Pakistan. Transbound Emerg Dis. 61 Suppl 1: 1–4.
15. Abubakar M, Rajput ZI, Arshed MJ, Sarwar G, Ali Q (2011) Evidence of peste des petits ruminants virus (PPRV) infection in Sindh Ibex (Capra aegagrusblythi) in Pakistan as confirmed by detection of antigen and antibody. Trop Anim Health Pro 43: 745-747.
16. Abubakar M, Rasool MH, Manzoor S, Saqalein M, Rizwan M, Munir M (2016). Evaluation of risk factors for peste des petits ruminants virus in sheep and goats at the Wildlife-Livestock Interface in Punjab Province, Pakistan. BioMed Res Int. 7826245. doi: 10.1155/2016/7826245.
17. Abu-Elzein EME, Housawi FMT, Bashareek Y, GameelAA, Al-Afaleq AI, et al. (2004) Severe PPR infection in gazelles kept under semi-free range conditions. J Vet Med B Infect Dis Vet Public Health 51: 68-71.
18. Afrika JG, Ajumbo G. (2012). Informal cross border trade in Africa: Implications and policy recommendations. Afr Econ Brief. 3: 1–13.
19. Agga GE, Raboisson D, Walch L, Alemayu F, Tesfaye D, Bahiru G (2019). Epidemiological survey of peste des petits ruminants in Ethiopia: cattle as potential sentinel for surveillance. Front Veterinary Sci. 6: 302. doi: 10.3389/fvets.2019.00302.
20. Ahmad K, Jamal S, Ali Q, Hussain M (2005) An outbreak of peste des petits ruminants in a goat flock in Okara, Pakistan. Pak Vet J 25: 146-148.
21. Albina E, Kwiatek O, Minet C, Lancelot R, de Almeida RS, Libeau G. (2013) Peste des petits ruminants, the next eradicated animal disease?. Veterinary Microbiol. 165: 38–44. doi: 10.1016/j.vetmic.2012.12.013.
22. Al-Dubaib MA (2008) Prevalence of peste des petits ruminants virus infection in sheep and goat farms at the central region of Saudi Arabia. RJVS 1: 67-70.
23. Al-Majali AM, Hussain NO, Amarin NM, Majok AA (2008) Seroprevalence of, and risk factors for, Peste des petits ruminants in sheep and goats in Northern Jordan. Pre Vet Med 85: 1-8.
24. Al-Naeem A, Elzein E, Al-Afaleq AI (2000) Epizootiological aspects of peste des petits ruminants and rinderpest in sheep and goats in Saudi Arabia. Rev Sci Tech Oie 19: 855-858.
25. Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR (2019). Taxonomy of the order Mononegavirales: update 2019. Arch Virol. 164: 1967–80. doi: 10.1007/s00705-019-04247-4.
26. Amjad H, Qamarul I, Forsyth M, Barrett T, Rossiter PB (1996) Peste des petits ruminants in goats in Pakistan. Vet. Rec 139: 118-119.
27. Anderson J, McKay JA (1994) The detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes. Epidemiol Infect 112: 225-231.
28. Anees M, Shabbir MZ, Muhammad K, Nazir J, Shabbir MA, Wensman JJ, et al. Genetic analysis of peste des petits ruminants virus from Pakistan. BMC Vet Res. 2013; 9: 60. doi: 10.1186/1746-6148-9-60.
29. Appel MJG, Gibbs EPJ, Martin SJ, Meulen VT, Rima BK, et al. (1981) Virus diseases of animals and man. Academic Press, New York.
30. Asil RM, Ludlow M, Ballal A, Alsarraj S, Ali WH, Mohamed BA, et al. First detection and genetic characterization of peste des petits ruminants virus from dorcas gazelles “Gazella dorcas” in the Sudan, 2016-2017. Arch Virol. (2019) 164: 2537–43. doi: 10.1007/s00705-019-04330-w.
31. Asim M, Rashid A, Chaudhary AH, Noor MS. Production Of Homologous Live Attenuated Cell Culture Vaccine For The Control Of Peste Des Petits Ruminants In Small Ruminants. Pakistan Vet J. 2009; 29 (2): 72–4.
32. Attieh E (2007) Enqueˆtese´ro-e´pide´miologiquesur les principals maladies caprines au Liban. EcoleNationaleVe´te´rinaire de Toulouse - ENVT.
33. Ayari-Fakhfakh E, Ghram A, Bouattour, A, Larbi I, Gribaa-Dridi L, et al. (2011) First serological investigation of peste-des-petits-ruminants and rift valley fever in Tunisia. Vet J 187: 402-404.
34. Bailey D, Banyard A, Dash P, Ozkul A, Barrett T (2005) Full genome sequence of peste des petits ruminants virus, a member of the Morbillivirus genus. Virus Res 110: 119-124.
35. Balamurugan V, Hemadri D, Gajendragad MR, Singh RK, Rahman H (2014) Diagnosis and control of peste des petits ruminants: a comprehensive review. Virus Dis 25: 39-56.
36. Balamurugan V, Sen A, Venkatesan G, Bhanot V, Yadav V, et al. (2012) Peste des petits ruminants virus detected in tissues from an Asiatic lion (Panthera Leo Persica) belongs to Asian lineage IV. J Vet Sci 13: 203-206.
37. Balamurugan V, Sen A, Venkatesan G, Yadav V, Bhanot V, et al. (2010) Sequence and phylogenetic analyses of the structural genes of virulent isolates and vaccine strains of peste des petites ruminants virus from India. Transbound Emerg Dis 57: 352-364.
38. Banyard AC, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gener Virol. (2010) 91: 2885–97. doi: 10.1099/vir.0.025841-0.
39. Banyard AC, Wang Z, Parida S. Peste des petits ruminants virus, eastern Asia. Emerg Infect Dis. (2014) 20: 2176–8. doi: 10.3201/eid2012.140907.
40. Bao J, Wang Z, Li L, Wu X, Sang P, et al. (2011) Detection and genetic characterization of peste des petits ruminants virus in free-living bharals (Pseudois nayaur) in Tibet, China. Res Vet Sci 90: 238-240.
41. Barhoom S, Hassan W, Mohammed T (2000) Iraqi Journal of Veterinary Sciences. Iraqi J Vet Sci 13: 381-385.
42. Baron J, Bin-Tarif A, Herbert R, Frost L, Taylor G, et al. (2014) Early changes in cytokine expression in peste des petits ruminants disease. Vet Res 45: 22.
43. Baron MD, Diop B, Njeumi F, Willett BJ, Bailey D. Future research to underpin successful peste des petits ruminants virus (PPRV) eradication. J General Virol. (2017) 98: 2635–44. doi: 10.1099/jgv.0.000944.
44. Bataille A, Baron MD, Liu F, Batten C, Wang Z, Libeau G. OIE reference laboratories for PPR provide support to the PPR Global Eradication Programme. In: PANORAMA 2018-2 OIE Buletin. Paris: OIE (2018). doi: 10.20506/bull.2018.2.2871.
45. Bataille A, Kwiatek O, Belfkhi S, Mounier L, Parida S, Mahapatra M, et al. Optimization and evaluation of a non-invasive tool for peste des petits ruminants surveillance and control. Sci Rep. (2019) 9: 4742. doi: 10.1038/s41598-019-41232-y.
46. Bazarghani TT, Charkhkar S, Doroudi J, Bani Hassan E (2006) A review on peste des petits ruminants (PPR) with special reference to PPR in Iran. J Vet Med B 53: 17-18.
47. Bedore B, Mustefa M, Tamire M, Geinoro T. Current status of occurrence and socio-economic impacts of peste des petits ruminants virus (PPRV) on small ruminant population in Ethiopia. Am J Epidemiol Public Health. (2019) 3: 12–6.
48. Berhe G, Minet C, Goff C, Barrett T, Ngangnou A, et al. (2003) Development of a dual recombinant vaccine to protect small ruminants against peste-des petits-ruminants virus and capripoxvirus infections. J Virol 77: 1571-1577.
49. Bidjeh K, Bornarel P, Imadine M, Lancelot R (1995) First- time isolation of the peste des petits ruminants (PPR) virus in Chad and experimental induction of the disease. Rev Elev Med Vet Pays Trop 48: 295-300.
50. Bora M, Yousuf RW, Dhar P, Singh RP. An overview of process intensification and thermo stabilization for upscaling of Peste des petits ruminants vaccines in view of global control and eradication. Virus Dis. (2018) 29: 285–96. doi: 10.1007/s13337-018-0455-3.
51. Borrow P, Oldstone MB (1995) Measles virus-mononuclear cell interactions. Curr Top MicrobiolImmunol 191: 85-100.
52. Brindha K, Raj GD, Ganesan PI, Thiagarajan V, Nainar AM, et al. (2001) Comparison of virus isolation and polymerase chain reaction for diagnosis of peste des petits ruminants. Acta Virol 45: 169-172.
53. Bundza AA, Afshar TW, Dukes DJ, Myers GD, Becker AWE (1988) Experimental PPR (goat plague) in goats and sheep. Can J Comp Med Vet Sci 52: 46-52.
54. Caufour P, Rufael T, Lamien CE, Lancelot, R, Kidane M, et al. (2014) Protective efficacy of a single immunization with capripoxvirus-vectored recombinant peste des petits ruminants vaccines in presence of pre-existing immunity. Vaccine 32: 3772-3779.
55. Chandran D, Reddy KB, Vijayan SP, Sugumar P, Rani GS, et al. (2010) MVA recombinants expressing the fusion and hemagglutinin genes of PPRV protects goats against vilrulent challenge. Indian J Microbiol 50: 266-274.
56. Chauhan HC, Chandel BS, Kher HN, Dadawala AI, Agrawal SM (2009) Pesti des petits ruminants virus infection in animals. Veterinary World 2: 150-155.
57. Chazya R, Muma JB, Mwacalimba KK, Karimuribo E, Mkandawire E, Simuunza M. A qualitative assessment of the risk of introducing peste des petits ruminants into northern Zambia from Tanzania. Veterinary Med Int. (2014) 2014: 202618. doi: 10.1155/2014/202618.
58. Chota A, Shirima G, Kusiluka L. Risk factors associated with Mycoplasma capricolum subspecies capripneumoniae and morbillivirus infection in small ruminants in Tanzania. Trop Anim Health Product. (2019) 51: 1807–15. doi: 10.1007/s11250-019-01981-4.
59. CIDRAP (2003) Peste des Petits Ruminants. Center for infectious diseases research and policy (CIDRAP). Academic health center, University of Minnesota.
60. Clarke BD, Islam MR, Yusuf MA, Mahapatra M, Parida S. Molecular detection, isolation and characterization of Peste-des-petits ruminants virus from goat milk from outbreaks in Bangladesh and its implication for eradication strategy. Transbound Emerg Dis. (2018) 65: 1597–604. doi: 10.1111/tbed.12911.
61. Cosby SL, Chieko K and Yamaguchi K. (2004) Rinderpest and Peste Des Petits Ruminants Virus: Plague of Large and Small Ruminants; Biology of Animal Infections. Academic Press, London, UK.
62. Couacy-Hymann E, Bodjo C, Danho T, Libeau G, Diallo A (2007) Evaluation of the virulence of some strains of PPR virus (PPRV) in experimentally infected West African dwarf goats. The Vet J 173: 178-183.
63. Couacy-Hymann E, Bodjo SC, Danho T, Koffi MY, Libeau G, et al. (2007) Early detection of viral excretion from experimentally infected goats with peste-des-petits ruminants virus. Pre Vet Med 78: 85-88.
64. Couacy-Hymann E, Roger F, Hurard C, Guillou JP, Libeau G, et al. (2002) Rapid and sensitive detection of peste des petits ruminants virus by a polymerase chain reaction assay. J Virol Methods 100: 17-25.
65. Couacy-Hymann ERF, Bidjeh K, Angba A, Domenech J, Diallo A (1995) Protection of goats against rinderpest by vaccination with attenuated peste des petits ruminants virus. Res Vet Sci 59: 106-109.
66. Covarrubias K, Nsiima L, Zezza A. Livestock and livelihoods in Rural Tanzania. A Descriptive Analysis of the 2009 National Panel Survey. (2012).
67. Das SC, Baron MD, Barrett T (2000) Recovery and characterization of a chimeric rinderpest virus with the glycoproteins of peste-des-petits ruminants virus: Homologous F and H proteins are required for virus viability. J Virol 74: 9039-9047.
68. DEFRA (2007) International disease monitoring Preliminary outbreak assessment: Peste des Petits Ruminants.
69. Delil F, Asfaw Y, Gebreegziabher B (2012) Prevalence of antibodies to peste des petits ruminants virus before and during outbreaks of the disease in Awashfentale district, Afar, Ethiopia. Trop Anim Health Pro 44: 1329-1330.
70. Dhar P, Sreenivasa BP, Barrett T, Corteyn M, Singh RP, Bandyopadhyay SK. Recent epidemiology of peste des petits ruminants virus (PPRV). Veterinary Microbiol. (2002) 88: 153–9. doi: 10.1016/S0378-1135(02)00102-5.
71. Diallo A, Barrett T, Barbron M, Subbarao SM, Taylor WP (1989) Differentiation of rinderpest and peste des petits ruminants viruses using specific cDNA clones. J Virol Methods 23: 127-136.
72. Diallo A, Minet C, Berhe G, Goff C, Black DN, et al. (2002) Goat immune response to capri pox vaccine expressing the hemagglutinin protein of peste des petits ruminants. Ann N Y Acad Sci, 969: 88-91.
73. Diallo A, Minet C, Le Goff C, Berhe G, Albina E, et al. (2007) The threat of peste des petits ruminants: Progress in vaccine development for disease control. Vaccine journal 25: 5591-5597.
74. Dundon WG, Diallo A, Cattoli G. Peste des petits ruminants in Africa: a review of currently available molecular epidemiological data, 2020. Arch Virol. (2020) 165: 2147–63. doi: 10.1007/s00705-020-04732-1.
75. Dundon WG, Kihu SM, Gitao GC, Bebora LC, John NM, Oyugi JO, et al. Detection and genome analysis of a lineage III peste des petits ruminants virus in Kenya in 2011. Transbound Emerg Dis. (2017) 64: 644–50. doi: 10.1111/tbed.12374.
76. Durojaiye OA (1987) Application of a precipitinogen inhibition test in the detection of antibody to peste des petits ruminants virus. Rev Elev Med Vet Pays Trop 40: 17-20.
77. Durrani A, Kamal N, Mehmood N, Shakoori A (2010) Prevalence of peste des petits ruminants (KATA) in sheep and goats of Punjab. Pac J Zool 42: 211-216.
78. ElArbi AS, Metras R, Hammami P, Ciss M, Beye A, Diallo A, et al. PPR control in a Sahelian Setting: what vaccination strategy for Mauritania. Front Veterinary Sci. (2019) 6: 242. doi: 10.3389/fvets.2019.00242.
79. El-Rahim IHAA, Baky MHA, Habashi AR, Mahmoud MM, Al-Mujalii DM (2005) Peste des petits ruminants among sheep and goats in Saudi Arabia in 2004. Assiut Vet. Med. J 51: 100-111.
80. Elsawalhy A, Mariner JC, Chibeu D, Wamway H, Wakhusama S, Olaho Mukani W, et al. Pan African strategy for the progressive control of peste des petits ruminants (Pan African PPR Strategy). Bullet Anim Health Produc Africa. (2011) 58: 185–93. doi: 10.4314/bahpa.v58i3.64206.
81. Esolen LM, Ward BJ, Moench TR, Griffin DE (1993) Infection of monocytes during Measles. JID 168: 47-52.
82. Ezeibe MC, Okoroafor ON, Ngene AA, Eze JI, Eze IC, et al. (2008) Persistent detection of peste de petits ruminants antigen in the faeces of recovered goats. Trop Anim Health Pro 40: 517-519.
83. Ezeibe MCO, Wosu LO, Erumaka IG (2004) Standardisation of the haemagglutination test for peste des petits ruminants (PPR). Small Ruminant Res 51: 269- 272.
84. FAO (1999) Recognizing Peste des Petits Ruminants: A field manual. Animal Production and Health Division. VialedelleTeme di Caracalla: Rome, Italy.
85. FAO and OIE. Peste des Petits Ruminants Global Eradication Programme. Rome: The Food and Agriculture Organization of the United Nations and the World Organisation for Animal Health (2016).
86. Felix N (2013) Current scenario and control initiatives for PPR at global, regional and country level according to the risk factors and socioeconomic impact. In Proceedings of the Second Regional Conference on Progressive Control of Peste Des Petits Ruminants in South Asia.
87. Forsyth MA, Barrett T (1995) Detection and differentiation of rinderpest and peste des petits ruminants viruses in diagnostic and experimental samples by polymerase chain reaction using P and F gene-specific primers. Virus Res 39: 151-63.
88. Forsyth MA, Parida S, Alexandersen S, Belsham GJ, Barrett T (2003) Rinderpest virus lineage differentiation using RT-PCR and SNAP-ELISA. J Virol Methods 107: 29-36.
89. Furley CW, Taylor WP, Obi TU (1987) An outbreak of peste des petits ruminants in a zoological collection. Vet Rec 121: 443-447.
90. Galbraith SE, McQuaid S, Hamill L, Pullen L, Barrett T, et al. (2002) Rinderpest and peste des petits ruminants viruses exhibit neurovirulence in mice. J Neurovirol 8: 45-52.
91. Gargadennec L, Lalanne A (1942) La peste des petits ruminants (in French). Bull Serv Zoot Epiz Afr Occ Fr 5: 16-21.
92. Gargadennec L, Lalanne A. La peste des petits ruminants. Bull des Serv Zootechniques et des Epizooties de l’Afrique Occidentale Francaise. (1942) 5: 16–21.
93. George A, Dhar P, Sreenivasa BP, Singh RP, Bandyopadhyay SK (2006) The M and N genes-based simplex and multiplex PCRs are better than the F or H gene-based simplex PCR for peste-despetits- ruminants virus. Acta Virol 50: 217-222.
94. Gibbs EP, Taylor WP, Lawman MJ, Bryant J (1979) Classification of peste des petits ruminants virus as the fourth member of the genus morbillivirus. Intervirology 11: 268-274.
95. Gibbs PJ, Taylor WP, Lawman MJ, Bryant J. Classification of peste des petits ruminants virus as the fourth member of the genus Morbillivirus. Intervirology. (1979) 11: 268–74. doi: 10.1159/000149044.
96. Gilbert Y, Monnier J (1962) Adaptation of the virus of peste des petits ruminants to tissue cultures. Revue Elev-Med. Vet Pays Trop 15: 321-335.
97. Gitao CG, Kihu SM, Bebora LC, Njenga JM, Wairire GG, Maingi N, et al. Comparison of Peste des petits ruminants (PPR) disease between Tanzania and Kenya. In: The 3rd RUFORUM Biennial Conference. (2012). Entebe.
98. Govindarajan R, Koteeswaran A, Venugopalan AT, Shyam G, Shaouna S, et al. (1997) Isolation of peste des petits ruminants virus from an outbreak in Indian buffalo (bubalus bubalis). Vet Rec 141: 573-574.
99. Griffin DE (1995) Immune responses during Measles virus infection. Curr Top Microbiol Immunol 191: 117-134.
100. Gur S, Albayrak H (2010) Seroprevalence of peste des petits ruminants (PPR) in goitered gazelle (Gazella subgutturosa subgutturosa) in Turkey. Journal of wildlife diseases 46: 673-677.
101. Gustafson CR, VanWormer E, Kazwala R, Makweta A, Paul G, Smith W, et al. Educating pastoralists and extension officers on diverse livestock diseases in a changing environment in Tanzania. Pastoralism. (2015) 5: 1–12. doi: 10.1186/s13570-014-0022-5.
102. Heaney J, Barrett T, Cosby SL (2002) Inhibition of in vitro leukocyte proliferation by morbilliviruses. J Virol 76: 3579-3584.
103. Herbert R, Baron J, Batten C, Baron M, Taylor G (2014) Recombinant adenovirus expressing the haemagglutinin of peste des petits ruminants virus (PPRV) protects goats against challenge with pathogenic virus; a DIVA vaccine for PPR. Vet Res 45: 24.
104. Herzog CM, de Glanville WA, Willett BJ, Cattadori IM, Kapur V, Hudson PJ, et al. Identifying age cohorts responsible for Peste des petits ruminants virus transmission among sheep, goats, and cattle in northern Tanzania. Viruses. (2020) 12: 186. doi: 10.3390/v12020186.
105. Herzog CM, de Glanville WA, Willett BJ, Cattadori IM, Kapur V, Hudson PJ, et al. Peste des petits ruminants virus transmission scaling and husbandry practices that contribute to increased transmission risk: an investigation among sheep, goats, and cattle in Northern Tanzania. Viruses. (2020) 12: 930. doi: 10.3390/v12090930.
106. Herzog CM, de Glanville WA, Willett BJ, Kibona TJ, Cattadori IM, Kapur V, et al. Pastoral production is associated with increased peste des petits ruminants seroprevalence in northern Tanzania across sheep, goats and cattle. Epidemiol Infect. (2019) 147: e242. doi: 10.1017/S0950268819001262.
107. Hickman CJ, Khan AS, Rota PA, Bellini, WJ (1997) Use of synthetic peptides to identify Measles nucleoprotein T-cell epitopes in vaccinated and naturally infected humans. Virology 235: 386-397.
108. Hoffmann B, Wiesner H, Maltzan J, Mustefa R, Eschbaumer M, et al. (2012) Fatalities in Wild Goats in Kurdistan Associated with Peste Des Petits Ruminants Virus. Transbound Emerg Dis 59: 173-176.
109. Housawi F, Abu Elzein E, Mohamed G, Gameel A, Al-Afaleq A, et al. (2004) Emergence of peste des petits ruminants virus in sheep and goats in Eastern Saudi Arabia. Revue d’elevageet de medecineveterinaire des pays tropicaux 57: 31-34.
110. Huygelen, C (1960) Failure to demonstrate agglutination of red blood cells by rinderpest virus. Bull Anim Health Prod Afr 8: 121-125.
111. Ilukor J. Improving the delivery of veterinary services in Africa: insights from the empirical application of transaction costs theory in Uganda and Kenya. Rev Sci Techn. (2017) 36: 279–89. doi: 10.20506/rst.36.1.2628.
112. Intizar M, Ahmad MD, Anjum AA, Hanif A. Comparative Efficacy Of Peste Des Petits Ruminants (PPR) Vaccines available in Pakistan in Sheep and Goats. Pakistan Vet J. 2009; 29 (4): 202–5.
113. Ismail IM, House J (1990) Evidence of identification of peste des petits ruminants from goats in Egypt. Arch Exp Veterinar med 44: 471-474.
114. Jagtap SP, Rajak KK, Garg UK, Sen A, Bhanuprakash V, et al. (2012) Effect of immunosuppression on pathogenesis of peste des petits ruminants (PPRV) virus infection in goats. Microb Pathog 52: 217-226.
115. Jones BA, Mahapatra M, Chubwa C, Clarke B, Batten C, Hicks H, et al. Characterisation of Peste Des Petits Ruminants Disease in pastoralist flocks in Ngorongoro District of Northern Tanzania and Bluetongue Virus Co Infection. Viruses. (2020) 12: 389. doi: 10.3390/v12040389.
116. Jones BA, Rich KM, Mariner JC, Anderson J, Jeggo M, Thevasagayam S, et al. The economic impact of eradicating peste des petits ruminants: a benefit-cost analysis. PLoS ONE. (2016) 11: e0149982. doi: 10.1371/journal.pone.0149982.
117. Kabir A, Abro DHKSH, Kalhoro MS, Yousafzai HA, Shams S, Khan IU, et al. Peste des petits ruminants: a review. Pure Appl Biol. (2019) 8: 1214–22. doi: 10.19045/bspab.2019.80063.
118. Kahn CM (2005) The Merck Veterinary Manual. (9 edtn) White House Station, New Jersey.
119. Kamwendo GC. Assessment of the epidemiological status, seroprevalence and molecular detection of Peste des Petits Ruminants in goats and sheep along Tanzania-Malawi Border (Doctoral dissertation) Sokoine University of Agriculture (2016) p. 45.
120. Kardjadj M. Epidemiological situation of transboundary animal diseases in North African countries—proposition of a regional control strategy. Trop Anim Health Product. (2018) 50: 459–67. doi: 10.1007/s11250-017-1453-y.
121. Karimuribo ED, Loomu PM, Mellau LSB, Swai E. Retrospective study on sero epidemiology of peste des petits ruminants before its official confirmation in northern Tanzania in 2008. Res Opini Anim Veterinary Sci. (2011) 1: 184–7.
122. Kaul R (2004) Hemagglutinin gene based molecular epidemiology of PPR virus. Dissertation, Indian Veterinary Research Institute, Izatnagar, Uttar Pradesh, India.
123. Kgotlele T, Chota A, Chubwa CC, Nyasebwa O, Lyimo B, Torsson E, et al. Detection of peste des petits ruminants and concurrent secondary diseases in sheep and goats in Ngorongoro district, Tanzania. Compar Clin Pathol. (2019) 28: 755–9. doi: 10.1007/s00580-018-2848-5.
124. Kgotlele T, Kasanga CJ, Kusiluka LJ, Misinzo G. Preliminary investigation on presence of peste des petits ruminants in Dakawa, Mvomero district, Morogoro region, Tanzania. Onderstepoort J Veterinary Res. (2014) 81: 2–4. doi: 10.4102/ojvr.v81i2.732.
125. Kgotlele T, Macha ES, Kasanga CJ, Kusiluka LJM, Karimuribo ED, Van Doorsselaere J, et al. Partial genetic characterization of peste des petits ruminants virus from goats in Northern and Eastern Tanzania. Transbound Emerg Dis. (2014) 61: 56–62. doi: 10.1111/tbed.12229.
126. Kgotlele T, Torsson E, Kasanga CJ. Seroprevalence of Peste Des Petits Ruminants virus from samples collected in different regions of Tanzania in 2013 and 2015. J Veterinary Sci Technol. (2016) 7: 1–5. doi: 10.4172/2157-7579.1000394.
127. Khalafalla AI, Saeed IK, Ali YH, Abdurrahman MB, Kwiatek O, et al. (2010) An outbreak of peste des petits ruminants (PPR) in camels in the Sudan. Acta Tropica 116: 161-165.
128. Khan HA, Siddique M, Abubakar M, Arshad MJ, Hussain M. Prevalence and distribution of peste des petits ruminants virus infection in small ruminants. Small Rumin Res. 2008; 79: 152–7.
129. Khan MA, Hussain SN, Bahadar S, Ali A, Shah IA. An outbreak of Peste des petits ruminants (PPR) in goats in district Chitral, N. W. F. P., Pakistan. J Agric Biol Sci. 2008; 3 (2): 19–22.
130. Kihu SM, Gitao GC, Bebora LC, John NM, Wairire GG, Maingi N, et al. Economic losses associated with Peste des petits ruminants in Turkana County Kenya. Pastoralism. (2015) 5: 9. doi: 10.1186/s13570-015-0029-6.
131. Kivaria FM, Kwiatek O, Kapaga AM, Swai ES, Libeau G, Moshy W, et al. The incursion, persistence and spread of peste des petits ruminants in Tanzania: epidemiological patterns and predictions. Onderstepoort J. Veterinary Res. (2014) 81: 593. doi: 10.4102/ojvr.v80i1.593.
132. Kul O, Kabakci N, Atmaca HT, Ozkul A (2007) Natural peste des petits ruminants virus infection: Novel pathologic findings resembling other Morbillivirus infections. Vet Pathol 44: 479-486.
133. Kulkarni DD, Bhikane AU, Shaila MS, Varalakshmi P, Apte MP, Narladkar BW. Peste des petits ruminants in goats in India. Veterinary Rec. (1996) 138: 187. doi: 10.1136/vr.138.8.187.
134. Kumar KS, Babu A, Sundarapandian G, Roy P, Thangavelu A, Kumar KS, et al. Molecular characterisation of lineage IV peste des petits ruminants virus using multi gene sequence data. Veterinary Microbiol. (2014) 174: 39–49. doi: 10.1016/j.vetmic.2014.08.031.
135. Kumar P, Tripathi BN, Sharma AK, Kumar R, Sreenivasa BP, et al. (2004) Pathological and immunohistochemical study of experimental Peste des petits ruminants virus infection in goats. J Vet Med B Infect Dis Vet Public Health 51: 153-159.
136. Kwiatek O, Ali YH, Saeed IK, Khalafalla AI, Mohamed OI, et al. (2011). Asian lineage of peste des petits ruminants virus, Africa. Emerg. Infect. Dis 17: 1223-1231.
137. Lefevre PC, Diallo A (1990) Peste des petits ruminants. Rev SciTechnol 9: 951-65.
138. Lefevre PCA, Diallo F, Schenkel S, Hussein G (1991) Serological evidence of peste des petits ruminants in Jordan. Vet Rec 128: 110.
139. Lembo T, Oura C, Parida S, Hoare R, Frost L, Fyumagwa R, et al. Peste des petits ruminants infection among cattle and Wildlife in Northern Tanzania. Emerg Infect Dis. 19: 2037–40. doi: 10.3201/eid1912.130973.
140. Libeau G, Diallo A, Calvez D, Lefevre PC (1992) A competitive ELISA using anti-N monoclonal antibodies for specific detection of RP antibodies in cattle and small ruminants. Vet Microbiol 31: 147-160.
141. Libeau G, Diallo A, Colas F, Guerre L (1994) Rapid differential diagnosis of RP and PPR using an immunocapture ELISA. Vet Rec 134: 300-4.
142. Little PD. Hidden Value on the Hoof: Cross-Border Livestock Trade in Eastern Africa. Common Market for Eastern and Southern Africa Comprehensive African Agriculture Development Program, Policy Brief number 2, February 2009. Midrand: CAADP (2009).
143. Liu F, Wu X, Liu W, Li L, Wang Z. Current perspectives on conventional and novel vaccines against peste des petits ruminants. Veterinary Res. Commun. 38: 307–22. doi: 10.1007/s11259-014-9618-x.
144. LPP (2006) Small stock in Development. International Livestock Production Programme (LPP).
145. Lyons NA, Jemberu WT, Chaka H, Salt JS, Rushton J. Field-derived estimates of costs for Peste des Petits Ruminants vaccination in Ethiopia. Prevent Veterinary Med. (2019) 163: 37–43. doi: 10.1016/j.prevetmed.2018.12.007.
146. Mahamat O, Doungous T, Kebkiba B, Oumar HA, Oussiguéré A, Yacoub AH, et al. Seroprevalence, geographical distribution, and risk factors of peste des petits ruminants in the Republic of Chad. J Adv Veterinary Animal Res. (2018) 5: 420. doi: 10.5455/javar.2018.e293.
147. Mahapatra M, Parida S, Baron MD, Barrett T (2006) Matrix protein and glycoproteins F and H of peste des petits ruminants virus function better as a homologous complex. J Gen Virol 87: 2021-2029.
148. Mahapatra M, Sayalel K, Muniraju M, Eblate E, Fyumagwa R, Shilinde S, et al. Spillover of peste des petits ruminants virus from domestic to wild ruminants in the Serengeti ecosystem, Tanzania. Emerg Infect Dis. (2015) 21: 2230–4. doi: 10.3201/eid2112.150223.
149. Majiyagbe KA, Nawathe DR, Abegunde A (1984) Rapid diagnosis of PPR infection, application of immuno-etectro-osmophoresis (IEOP) technique. Rev Elev Med Vet Pays Trop 37: 11-15.
150. Manual for PPR detection. (2005) EMPRES (Livestock) Animal Production and Health Division Vialedelle Terme di Cara-calla 00100 Rome, Italy.
151. Marie JC, Kehren J, Trescol-Biemont MC, Evlashev A, Valentin H, et al. (2001) Mechanism of Measles virus-induced suppression of inflammatory immune responses. Immunity 14: 69-79.
152. Mariner JC, House JA, Mebus CA, van den Ende MC (1993) The use of thermostable Vero cell-adapted rinderpest vaccine as a heterologous vaccine against peste des petits ruminants. Res Vet Sci 54: 212-216.
153. Mariner JC, Jones BA, Rich KM, Thevasagayam S, Anderson J, Jeggo M, et al. The opportunity to eradicate Peste des Petits Ruminants. J Immunol. (2016) 196: 3499–506. doi: 10.4049/jimmunol.1502625.
154. Matthew M, Mruttu H, Gebru G. Animal Health Strategy and Vision for Tanzania. Nairobi: Tanzania Ministry of Agriculture, Livestock and Fisheries and International Livestock Research Institute (ILRI) (2016).
155. Mbyuzi AO, Komba EV, Kimera SI, Kambarage DM. Sero-prevalence and associated risk factors of peste des petits ruminants and contagious caprine pleuro-pneumonia in goats and sheep in the Southern Zone of Tanzania. Prevent Veterinary Med. (2014) 116: 138–44. doi: 10.1016/j.prevetmed.2014.06.013.
156. Mbyuzi AO, Komba EVG, Cordery-Cotter R, Magwisha HB, Kimera SI, Kambarage DM. Descriptive survey of Peste des Petits Ruminants and Contagious Caprine Pleuropneumonia outbreaks in traditional goat flocks in Southern Tanzania: producers concerns, knowledge and attitudes. Livestock Res Rural Dev. (2015) 27: 1–9.
157. Mdetele D, Mwakabumbe S, Seth M, Madege M. Evaluation of effectiveness of pest des petits ruminants vaccine in Northern Tanzania. Res Opin Anim Veterinary Sci. (2015) 5: 401–5.
158. Mdetele D, Seth M, Kabululu M, and Misinzo G. (2020). A comparative study of the sero-prevalence of Peste Des Petits Ruminants Virus among districts of different agro-ecological zones in Tanzania. East Af J Sci Technol Innovat. 1: 1–12. doi: 10.37425/eajsti.v1i3.167.
159. Megersa B, Biffa D, Abunna F, Regassa A, Bohlin J, et al. (2012). Epidemic characterization and modeling within herd transmission dynamics of an “emerging trans-boundary” camel disease epidemic in Ethiopia. Trop Anim Health Pro 44: 1643-1651.
160. Mehmood A, Qurban A, Gadahi AJ, Malik SA, Syed IS (2009) Detection of peste des petits ruminants (PPR) virus antibodies in sheep and goat populations of the North West Frontier Province (NWFP) of Pakistan by competitive ELISA (cELISA). Veterinary World 2: 333-336.
161. Michael S, Mbwambo N, Mruttu H, Dotto MM, Ndomba C, da Silva M, et al. Tanzania Livestock Master Plan Developed by the Tanzania Ministry of Livestock and Fisheries (MLF) and the International Livestock Research Institute (ILRI) Livestock Master Plan Team. (2018). Available online at: https://cgspace.cgiar.org/bitstream/handle/10568/92405/ livestockMasterPlan.Tanzania.pdf?sequence=1 (accessed December, 2019).
162. Misinzo G, Kgotlele T, Muse EA, Van Doorsselaere J, Berg M, Munir M. Peste des petits ruminants virus lineage II and IV from goats in southern tanzania during an outbreak in 2011. Br J Virol. (2015) 2: 1–4.
163. Mondal B, Sreenivasa BP, Dhar P, Singh RP, Bandyopadhyay SK (2001) Apoptosis induced by peste des petits ruminants virus in goat peripheral blood mononuclear cells. Virus Res 73: 113-119.
164. Mornet P, Orue J, Gilbert Y, Thiery G, Sow M (1956). La peste des petits ruminants en AfriqueOccidentaleFrançaise. Ses rapports avec la peste bovine. Revue d’e´levageet de me´decineve´te´rinaire des paystropicaux 9: 313-342.
165. Moumin G, Moussa C, Teshale S, Gezahegne M. Seroprevalence and risk factors for peste des petits ruminants in sheep and goats in Djibouti. Rev Sci Tech. (2018) 37: 961–9. doi: 10.20506/37.3.2899.
166. Munir M (2013) Mononegaviruses of Veterinary Importance, Pathobiology and Molecular Diagnosis; CABI International. Oxfordshire, UK.
167. Munir M (2015) Pathology of Peste des Petits Ruminants Virus Infection in Small Ruminants and Concurrent Infections, Peste des Petits Ruminants Virus.
168. Munir M. Role of wild small ruminants in the epidemiology of peste des petits ruminants. Transbound Emerg Dis. (2014) 61: 411–24. doi: 10.1111/tbed.12052.
169. Muse EA, Karimuribo ED, Gitao C, Misinzo G, Mellau LS, Msoffe PL, et al. Epidemiological investigation into the introduction and factors for spread of Peste des Petits Ruminants, southern Tanzania. Onderstepoort J. Vet Res. (2012) 79: 49–54. doi: 10.4102/ojvr.v79i2.457.
170. Muse EA, Matondo RB, Karimuribo ED, Misinzo G, Mellau LSB, Msoffe PLMAMO, GGC. Peste des Petits Ruminants (PPR) outbreak in southern, Tanzania. In: The 3rd RUFORUM Biennial Conference, 24th – 28th September 2012. Entebbe (2012). p. 1–3.
171. Naik S, Renukaradhya GJ, Rajasekhar M, Shaila MS (1997) Immunogenic and protective properties of haemagglutinin protein (H) of rinderpest virus expressed by a recombinant baculovirus. Vaccine 15: 603-607.
172. Namtimba AM. Seroprevalence and genetic characterisation Of Peste Des Petits Ruminants Virus in selected areas of Tanzania. Morogoro: Sokoine University of Agriculture (2015).
173. Nawathe DR, Taylor WP (1979) Experimental infection of domestic pigs with the virus of peste des petits ruminants. Trop Anim Health Prod 11: 120-122.
174. Niyokwishimira A, de D Baziki J, Dundon WG, Nwankpa N, Njoroge C, Boussini H, et al. Detection and molecular characterization of Peste des Petits Ruminants virus from outbreaks in Burundi, December 2017–January 2018. Transbound Emerg Dis. (2019) 66: 2067–73. doi: 10.1111/tbed.13255.
175. Njeumi F, Bailey D, Soula J, Diop B, Tekola BG. Eradicating the Scourge of Peste Des Petits Ruminants from the World. Viruses. (2020) 12: 313. doi: 10.3390/v12030313.
176. Nkangaga JJ, Matondo AB, Karimuribo E. Peste des petits ruminants (PPR) in western Tanzania. Tanzania Veterinary J. (2019) 34: 44–53.
177. Nkangaga JJ. Disease Status And Risk Factors for Peste Des Petits Ruminants Along Tanzania-Burundi and Democratic Republic of Congo Border. Morogoro: Sokoine University of Agriculture (2014).
178. Obi TU, Ojeh CK (1989) Dot enzyme immuno assay for visual detection of Peste des Petits ruminants virus antigen from infected caprine tissues. J Clin Microbiol 27: 2096-2099.
179. Odo BI. Comparative study of some prevalent diseases of ecotype goats reared in southeastern Nigeria. Small Rumin. Res. 50, 203–207, Petits Ruminanants: A Field Manual. FAO Anim Health Manual. 2003; 5: 28–207.
180. Ohishi K, Inui K, Yamanouchi K, Barrett T (1999) Cell-mediated immune responses in cattle vaccinated with a vaccinia virus recombinant expressing the nucleocapsid protein of rinderpest virus. J Gen Virol 80: 1627-1634.
181. OIE. Peste des Petits Ruminant Technical Disease card, Animals. (2009). p. 1–6.
182. OIE. Peste des Petits Ruminants (Infection With Peste des Petits Ruminants) in OIE Terrestrial Mannual 2019. (2019). p. 1–16.
183. Olaleye OD, Oyejide A, Ikede BO (1989) Correlation of humoral immune response with clinical presentation, pulmonary lesions and mortality patterns of goats experimentally infected with peste des petits ruminants virus. Cytobios 57: 141-147.
184. Osman NA, Rahman MEA, Ali AS, Fadol MA (2008) Rapid detection of Peste des Petits Ruminants (PPR) virus antigen in Sudan by agar gel precipitation (AGPT) and haemagglutination (HA) Tests. Trop Anim Health Prod 40: 363-368.
185. Osunkoya BO, Ukaejiofo EO, Ajayi O, Akinyemi AA (1990) Evidence that circulating lymphocytes act as vehicles or viraemia in Measles. West Afr J Med 9: 35-39.
186. Ozkul A, Akca Y, Alkan F, Barrett T, Karaoglu T, et al. (2002) Prevalence, distribution and host range of peste des petits ruminants virus, Turkey. Emerg Infect Dis 8: 708-712.
187. Pandey KD, Baron MD, Barrett T (1992) Differential diagnosis of rinderpest and PPR using biotinylated cDNA probes. Vet Rec 131: 199-200.
188. Parida S, Muniraju M, Altan E, Baazizi R, Raj GD, Mahapatra M. Emergence of PPR and its threat to Europe. Small Ruminant Res. (2016) 142: 16–21. doi: 10.1016/j.smallrumres.2016.02.018.
189. Parida S, Selvaraj M, Gubbins S, Pope R, Banyard A, Mahapatra M. Quantifying levels of peste des petits ruminants (PPR) virus in excretions from experimentally infected goats and its importance for nascent PPR eradication programme. Viruses. (2019) 11: 249. doi: 10.3390/v11030249.
190. Pasick J. Application of DIVA vaccines and their companion diagnostic tests to foreign animal disease eradication. Anim Health Res Rev. (2004) 5: 257–62. doi: 10.1079/AHR200479.
191. Pegram RG, Tereke F. Observation on the health of Afar livestock. Ethiop Veterinary J. (1981) 5: 11–4.
192. Pope RA, Parida S, Bailey D, Brownlie J, Barrett T, et al. (2013) Early events following experimental infection with peste-des-petits ruminants virus suggest immune cell targeting. PLoS One, 8: e55830.
193. Pruvot M, Fine AE, Hollinger C, Strindberg S, Damdinjav B, Buuveibaatar B, et al. Outbreak of Peste des Petits Ruminants among critically endangered Mongolian Saiga and Other Wild Ungulates, Mongolia, 2016–2017. Emerg Infect Dis. (2020) 26: 51. doi: 10.3201/eid2601.181998.
194. Qin J, Huang H, Ruan Y, Hou X, Yang S, et al. (2012) A novel recombinant Peste des petits ruminants-canine adenovirus vaccine elicits long-lasting neutralizing antibody response against PPR in goats. PLoS One 7: e37170.
195. Radostitis OM, Blood DC, Gray, CC (2007) Veterinary Medicine: A Text book of the Disease of Cattle, Horse, Sheep, Pigs and Goats. (10 edtn), London, Elsevier.
196. Radostits OM, Gay CC, Blood DC, Hinchcliff KW. Veterinary Medicine. 9th ed. London: W. B. Saunders Company Ltd; 2000. p. 563–5.
197. Rahaman A, Srinivasan N, Shamala N, Shaila MS (2003) The fusion core complex of the Peste des petits ruminants virus is a six-helix bundle assembly. Biochemistry 42: 922-931.
198. Rajak KK, Sreenivasa BP, Hosamani M, Singh RP, Singh SK, et al. (2005) Experimental studies on immunosuppressive effects of peste des petits ruminants (PPR) virus in goats. Comp Immunol Microbiol Infect Dis 28: 287- 296.
199. Rajko-Nenow P, Flannery J, Arnold H, Howson EL, Darpel K, Stedman A, et al. A rapid RT-LAMP assay for the detection of all four lineages of Peste des Petits Ruminants virus. J Virol Methods. (2019) 274: 113730. doi: 10.1016/j.jviromet.2019.113730.
200. Ramachandran S, Hedge NR, Raghavan R, Subbarao S, Shyam G (1993) Haemagglutination by PPR virus. Proceedings of The 3rd International Sheep Veterinary Conference.
201. Rashid A, Asim M, Hussain A (2008) An outbreak of peste des petits ruminants in goats in Lahore. J Anim Plant Sci 18: 72-75.
202. Roeder PL, Abraham G, Kenfe G, Barrett T. Peste des petits ruminants in Ethiopian goats. Trop Anim Health Product. (1994) 26: 69–73. doi: 10.1007/BF02239901.
203. Roger F, Diallo A, Yigezu, LM, Hurard C, Libeau G, et al. (2000) Investigation of a new pathological condition of camels in Ethiopia. J Camel Pract Res 2: 163-165.
204. Romero CH, Barrett T, Kitching RP, Carn VM, Black DN (1994) Protection of cattle against rinderpest and lumpy skin disease with a recombinant capripoxvirus expressing the fusion protein gene of rinderpest virus. Vet Rec 135: 152-154.
205. Roos N. Seroepidemiology of Peste des petits Ruminants in central Tanzania Alongside an Evaluation of Filter Paper as Transport Medium. Uppsala: Swedish University of Agricultural Sciences Faculty (2016).
206. Salih HAM, Elfadil AAM. Preliminary qualitative risk assessment for Peste des petits ruminants (PPR) in sheep exported from Sudan during 2012. J Veterinary Sci Med. (2016) 4: 9. doi: 10.13188/2325-4645.1 000021.
207. Saliki JT, House JA, Mebus CA, Dubovi EJ (1994) Comparison of monoclonal antibodies-based sandwich ELISA and virus isolation for detection of PPR virus in goats tissue and secretion. J Clin Microbiol 32: 1349-1353.
208. Saravanan P, Sena, A, Balamurugan V, Rajak KK, Bhanuprakash V, et al. (2010) Comparative efficacy of peste des petits ruminants (PPR) vaccines. Biologicals 38: 479-485.
209. Sarkar J, Sreenivasa BP, Singh RP, Dhar P, Bandyopadhyay SK (2003) Comparative efficacy of various chemical stabilizers on the thermostability of a live-attenuated peste des petits ruminants (PPR) vaccine. Vaccine 21: 4728-4735.
210. Schlender J, Schnorr JJ, Spielhoffer P, Cathomen T, Cattaneo R, et al. (1996) Interaction of Measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro. Proc Natl Acad Sci USA 93: 13194-13199.
211. Schneider-Schaulies S, Niewiesk S, Schneider-Schaulies J, terMeulen V (2001) Measles virus induced immunosuppression: Targets and effector mechanisms. Curr Mol Med 1: 163-181.
212. Sen A, Saravanan P, Balamurugan V, Rajak KK, Sudhakar SB, Bhanuprakash V, et al. Vaccines against peste des petits ruminants virus. Exp Rev Vac. (2010) 9: 785–96. doi: 10.1586/erv.10.74.
213. Sghaier S, Cosseddu GM, Hassen SB, Hammami S, Ammar HH, Petrini A, et al. Peste des petits ruminants virus, Tunisia, 2012–2013. Emerg Infect Dis. (2014) 20: 2184. doi: 10.3201/eid2012.141116.
214. Shaila MS, David S, Foryth MA, Diallo A, Goatley L, et al. (1996) Geographical distribution and epidemiology of PPR viruses. Virus Res 43: 149-153.
215. Shaila MS, Purushothaman V, Bhavasar D, Venugopal K, enkatesan RA (1989) Peste des petits ruminants of sheep in India. Vet Rec 125: 602.
216. Shaila MS, Shamaki D, Forsyth MA, Diallo A, Goatley L, Kitching RP, et al. (1996). Geographic distribution and epidemiology of peste des petits ruminants viruses. Virus Res. 43: 149–53. doi: 10.1016/0168-1702(96)01312-3.
217. Sharawi SS, Yousef MR, Al-Hofufy AN, Al-Blowi M (2010) Isolation, Serological and Real time PCR diagnosis of Peste Des Petites Ruminants virus in naturally exposed Arabian Gazelle in Saudi Arabia. Vet World 3: 489- 494.
218. Shubber EK, Zenad MM, Al-Bana AS, Hamdan GE, Shahin MG, et al. (2004) Serosurveillance of peste des petits ruminants virus antibodies in Iraq. Iraqi J Vet Sci 18: 139-144.
219. Singh RK, Balamurugan V, Bhanuprakash V, Sen A, Saravanan P, et al. (2009) Possible control and eradication of peste des petits ruminants from India, Technical aspects. Vet Ital 45: 449-462.
220. Singh RP, Bandyopadhyay SK. Peste des petits ruminants vaccine and vaccination in India: sharing experience with disease endemic countries. Virus Dis. (2015) 26: 215–24. doi: 10.1007/s13337-015-0281-9.
221. Singh RP, De UK, Pandey KD (2010) Virological and antigenic characterization of two peste des petits ruminants (PPR) vaccine viruses of Indian origin. Comp Immunol Microb 33: 343-353.
222. Singh RP, Sreenivasa BP, Dhar P, Bandyopadhyay SK (2004) A sandwich ELISA for the diagnosis of Peste des petits ruminants (PPR) infection in small ruminants using anti-nucleocapsid protein monoclonal antibody. Arch Virol 149: 2155-70.
223. Singh RP. Control strategies for peste des petits ruminants in small ruminants of India. Rev Sci Techni-OIE. (2011) 30: 879. doi: 10.20506/rst.30.3.2079.
224. Sinnathamby G, Naik S, Renukaradhya GJ, Rajasekhar M, Nayak R, et al. (2001) Recombinant hemagglutinin protein of rinderpest virus expressed in insect cells induces humoral and cell mediated immune responses in cattle. Vaccine 19: 3870-3876.
225. Sinnathamby G, Nayak R, Shaila MS (2001) Mapping of T-helper epitopes of rinderpest virus hemagglutinin protein. Viral Immunol 14: 83-92.
226. Sinnathamby G, Renukaradhya GJ, Rajasekhar M, Nayak R, Shaila MS (2001) Immune responses in goats to recombinant hemagglutininneuraminidase glycoprotein of peste des petits ruminants virus: Identification of a T-cell determinant. Vaccine 19: 4816-4823.
227. Spiegel KA, Havas KA. The socioeconomic factors surrounding the initial emergence of peste des petits ruminants in Kenya, Uganda, and Tanzania from 2006 through 2008. Transbound Emerg Dis. (2019) 66: 627–33. doi: 10.1111/tbed.13116.
228. Sreenivasa BP, Dhar P, Singh RP, Bandyopadhyay SK (2002) Development of peste des petits ruminants (PPR) challenge virus from a field isolate. XIV Annual Conference and National Seminar on Management of Viral Diseases with Emphasis on Global Trade and WTO Regime of Indian Virological Society.
229. Sreenivasa BP, Singh RP, Mondal B, Dhar P, Bandyopadhyay SK (2006) Marmoset B95a cells: a sensitive system for cultivation of peste des petits ruminants (PPR) virus. Vet Res Commun 30: 103-8.
230. Swai ES, Kapaga A, Kivaria F, Tinuga D, Joshua G, Sanka P. Prevalence and distribution of Peste des petits ruminants virus antibodies in various districts of Tanzania. Veterinary Res Commun. (2009) 33: 927–36. doi: 10.1007/s11259-009-9311-7.
231. Swai ES, Moshy W, Mbise E, Kaaya J, Bwanga S. (2011). Serological evidence of camel exposure to Peste des Petits Ruminants virus in Tanzania. Res Opin Anim Veterinary Sci. 1: 325–9. doi: 10.1007/s11250-014-0747-6.
232. Taylor WP (1979) Protection of goats against peste des Petits Ruminants with attenuated rinderpest virus. Res Vet Sci 27: 321-324.
233. Taylor WP (1984) The distribution and epidemiology of PPR. Pre Vet Med 2: 157-166.
234. Taylor WP (1984) The distribution and prevalence of Peste des Petits Ruminants. Global Veterinaria 3: 281-285.
235. Taylor WP, Abegunde A (1979) The isolation of peste des petits ruminants virus from Nigerian sheep and goats. Res Vet Sci 26: 94-96.
236. Taylor WP, Busaidy S, Barrett T (1990) The epidemiology of peste des petits ruminants in the Sultanate of Oman. Vet Microbiol 22: 341-352.
237. Taylor WP, Diallo A, Gopalakrishna S, Sreeramalu P, Wilsmore AJ, et al. (2002) Peste des petits ruminants has been widely present in southern India since, if not before, the late 1980s. Pre Vet Med 52: 305-312.
238. Thombare NN, Sinha MK. Economic implications of peste des petits ruminants (PPR) disease in sheep and goats: a sample analysis of district Pune, Maharastra. Agric Econ Res Rev. (2009) 22: 319–22. doi: 10.22004/ag.econ.57469.
239. Toplu N, Oguzoglu TC, Albayrak H (2012) Dual infection of fetal and neonatal small ruminants with border disease virus and peste des petits ruminants virus (PPRV): Neuronal tropism of PPRV as a novel finding. J Comp Pathol 146: 289-297.
240. Torsson E, Berg M, Misinzo G, Herbe I, Kgotlele T, Päärni M, et al. Seroprevalence and risk factors for peste des petits ruminants and selected differential diagnosis in sheep and goats in Tanzania. Infect Ecol Epidemiol. (2017) 7. doi: 10.1080/20008686.2017.1368336.
241. Torsson E, Kgotlele T, Berg M, Mtui-Malamsha N, Swai ES, Wensman JJ, et al. History and current status of peste des petits ruminants virus in Tanzania. Infect Ecol Epidemiol. (2016) 6: 1–7. doi: 10.3402/iee.v6.32701.
242. Tshilenge GM, Walandila JS, Kikukama DB, Masumu J, Balowa LK, Cattoli G, et al. Peste des petits ruminants viruses of lineages II and III identified in the Democratic Republic of the Congo. Veterinary Microbiol. (2019) 239: 108493. doi: 10.1016/j.vetmic.2019.108493.
243. Ugochukwu EI Agwu CO (1991) Aerobic bacteria from nasal discharge of goats suffering from clinical PPR: Isolation and identification. Microbios 65: 81-85.
244. Ugochukwu IC, Ezeasor CK, Agina OA, Anyogu DC, Chukwudi IC, Idoko SI, et al. Peste des petits ruminants: aetiology, pathology, immunology, disease status in Africa, diagnosis, control, prevention and treatment: a review. Notulae Scientia Biol. (2019) 11: 12–20. doi: 10.15835/nsb11110355.
245. Wang Y, Liu G, Chen Z, Li C, Shi L, et al. (2013) Recombinant adenovirus expressing F and H fusion proteins of peste des petits ruminants virus induces both humoral and cell-media.
246. Wilson RT. The Red Meat Value Chain in Tanzania A Report From the Southern Highlands Food Systems Programme. Food and Agriculture Organization of the United Nations (FAO) (2013). p. 14–36.
247. Wohlsein P, Saliki J (2006) Rinderpest and peste des petits ruminants - the diseases: clinical signs and pathology. In: Rinderpest and Peste des Petits Ruminants. Academic Press, London, Burlington, San Diego.
248. Woo PC, Lau SK, Wong BH, Fan RY, Wong AY, et al. (2012) Feline Morbillivirus, a previously undescribed Paramyxovirus associated with tubulointerstitial nephritis in domestic cats. Proc Natl Acad Sci U S A 109: 5435-5440.
249. Wosu LO (1985) Agglutination of red blood cells by peste des petits ruminants (PPR) virus. Niger Vet J 14: 56-58.
250. Wosu LO (1991) Haemagglutination test for diagnosis of peste des petits ruminants disease in goats with samples from live animals. Small Ruminant Res 5: 169-172.
251. Yanagi Y, Takeda M, Ohno S (2006) Measles virus: Cellular receptors, tropism and pathogenesis. J. Gen. Virol 87: 2767-2779.
252. Yesilbag K, Yilmaz Z, Golcu E, Ozkul A (2005) Peste des petits ruminants outbreak in Western Turkey. Vet Rec 157: 260-261.
253. Yokota S, Saito H, Kubota T, Yokosawa N, Amano K, et al. (2003) Measles virus suppresses interferon-alpha signaling pathway: Suppression of JAK1 phosphorylation and association of viral accessory proteins, C and V, with interferon-alpha receptor complex. Virology 306: 135-146.
254. Yoneda M, Bandyopadhyay SK, Shiotani M, Fujita K, Nuntaprasert A, et al. (2002) Rinderpest virus H protein: Role in determining host range in rabbits. J Gen Virol 83: 1457-1463.
255. Yoneda M, Miura R, Barrett T, Tsukiyama-Kohara K, Kai C (2004) Rinderpest virus phosphoprotein gene is a major determinant of species-specific pathogenicity. Virology 78: 6676-6681.
256. Zahur AB, Ullah A, Irshad H, Farooq MS, Hussain M, et al. (2009) Epidemiological investigations of a peste des petits ruminants (PPR) outbreak in Afghan sheep in Pakistan. Pak Vet J 29: 174-178.
257. Zahur AB, Ullah A, Irshad H, Latif A, Ullah RW, Jahangir M, et al. Epidemiological analysis of Peste des Petits Ruminants (PPR) outbreaks in Pakistan. J Biosci Med. (2014) 2: 18. doi: 10.4236/jbm.2014.26004.
258. Zakian A, Nouri M, Kahroba H, Mohammadian B, Mokhber-Dezfouli M (2016) The first report of peste des petits ruminants (PPR) in camels (Camelus dromedarius) in Iran. Trop Anim Health Prod 48: 1215-1219.