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Research Article |

Design of an Effective Nutraceutical (“SR45”) for Low Mood Management

Introduction: Herbal products play a crucial role in traditional Chinese medicine, offering a holistic approach to disease treatment. Botanicals and their active components have shown promise in addressing depression-like symptoms. Unlike antidepressant medications, botanicals offer a natural alternative with milder side effects. This study explores the potential of botanical compounds as antidepressants. Natural Products for Low Mood Management: Crocus Sativus (Saffron): Derived from the Crocus sativus flower, saffron has demonstrated effectiveness in relieving symptoms of mild to moderate anxiety, comparable to standard antidepressants. Cost-effective petal extracts have proven to be viable alternatives. Rhodiola Rosea (Rhodiola): Used traditionally to enhance physical and mental performance, Rhodiola extracts have shown promise in reducing anxiety and depression symptoms. Development of SR45: Bioactive compounds hold significant potential for enhancing nutraceutical functionality. Encapsulation systems have emerged as a transformative technology for improving bioactive stability and bioavailability. SR45, developed with Rhodiola on a lipid basis and advanced encapsulation techniques, aims to enhance the bioavailability of key bioactive ingredients. Preliminary Clinical Results Obtained with SR45: A randomized clinical trial evaluated SR45's efficacy and safety in individuals with low mood. Participants taking SR45 experienced a statistically significant reduction in depression and anxiety symptoms compared to the placebo group. Both groups showed improvement, highlighting the placebo effect, essential for robust study execution. No adverse events related to SR45 were observed, indicating its safety. Conclusions: Daily consumption of SR45 capsules over 8 weeks led to a reduction in depression in individuals with mild symptoms. SR45 also demonstrated effectiveness in reducing anxiety in individuals with mild to moderate symptoms. SR45 was found to be safe for consumption at the specified doses over the 8-week period. This preliminary study suggests that SR45 holds promise as a natural supplement for managing low mood. Further research is warranted to validate these findings and explore the potential of SR45 in a larger population.

Crocus Sativus, Rhodiola Rosea, Low Mood

APA Style

Moran, J. (2023). Design of an Effective Nutraceutical (“SR45”) for Low Mood Management. World Journal of Food Science and Technology, 7(4), 77-80.

ACS Style

Moran, J. Design of an Effective Nutraceutical (“SR45”) for Low Mood Management. World J. Food Sci. Technol. 2023, 7(4), 77-80. doi: 10.11648/j.wjfst.20230704.11

AMA Style

Moran J. Design of an Effective Nutraceutical (“SR45”) for Low Mood Management. World J Food Sci Technol. 2023;7(4):77-80. doi: 10.11648/j.wjfst.20230704.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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