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Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes

Schiff bases are aldehyde or ketone derivatives that are made by condensation of primary amines and carbonyl compounds and have their carbonyl organization (C = O) replaced by an imine or azomethine organization (>C = N-). Schiff bases are a key ligand elegance in coordination chemistry and are widely used in a variety of fields. Metallic buildings have extra organic action than the relating ligands. Schiff base complexes in particular are particularly intriguing due to their stability, electron-donating potential, photochromic, optical nonlinearity properties, and biological interest. The coordination of Schiff bases with steel ions serves as the foundation for each one. With -NH2 and -COOH coordination sites, amino acids are functionally important in many biological processes and form Schiff bases that easily coordinate with metallic ions when combined with aldehydes or ketones. The majority of Schiff bases derived from amino acids and their metallic complexes exhibit specific pharmacological properties. This assess centers around research related with Schiff base buildings of amino corrosive subordinates throughout the course of recent years. We spotlight the antimicrobial, anticancer and cell reinforcement amino acids of a couple of Schiff base mixtures with nitrogen, oxygen and sulfur contributors and different metallic particles.

Schiff Base Complexes, Synthesis, Characterization, Biological Activity

APA Style

Desalegn Tesfa Tefera. (2023). Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes. World Journal of Applied Chemistry, 8(2), 22-33.

ACS Style

Desalegn Tesfa Tefera. Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes. World J. Appl. Chem. 2023, 8(2), 22-33. doi: 10.11648/j.wjac.20230802.11

AMA Style

Desalegn Tesfa Tefera. Synthesis, Characterization and Biological Activities of Schiff Bases and Their Transition Metal Complexes. World J Appl Chem. 2023;8(2):22-33. doi: 10.11648/j.wjac.20230802.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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