Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere

Rachida Elosrouti; Brahim Sallek; Hassan Chaair; Khalid Digua; Hassan Oudadesse

doi:doi:10.11648/j.sr.20150301.11

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Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere

Rachida Elosrouti, Brahim Sallek, Hassan Chaair, Khalid Digua, Hassan Oudadesse

Published in Science Research (Volume 3, Issue 1)

Received: 28 November 2014 Accepted: 17 December 2014 Published: 26 January 2015

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Abstract

Hydroxyapatite (Ca10 (PO4)6 (OH)2, HAP) is widely used as a bone graft substitute, potential carriers of drugs and in the purification of proteins, et could be synthesized artificially by various methods but the hydrothermal method at low temperature, which gives a good crystallinity, is often used. Moreover, several studies have shown that, in the synthesis of calcium phosphate, the nature of the final product may differ depending on the experimental conditions including the value of the initial Ca / P ratio, the nature of the calcium salts used and influence of the residence time of the initial products used in experimental conditions. Thus, in this work, while maintaining the initial Ca / P ratio to a fixed value (1,00 ± 0,01), we followed the behavior of two initial mixtures of a calcium salt and one of two other phosphate salts (di-ammonium hydrogen phosphate and di-ammonium hydrogen phosphate) as a function of residence time in an autoclave at a temperature of 80 °C in a saturated water vapor environment. The characteristics of the final product were carried out by four methods: X-ray diffraction, infrared absorption spectroscopy in the range 400 cm-1 _ 4000 cm-1, chemical analysis, and scanning electron microscopy. The XRD analysis has shown that the products obtained have all an apatite structure. They show the presence, alongside that of apatite, the identifiable stripes of the calcite for the residence times in the experience that are less than 48 hours. Similarly, the infrared absorption spectroscopy for short residence times ranging from 2 hours to 8 am always have shown the presence of the bands specific to the CO32- ions which are fit for calcite and which decrease by increasing the residence time. Beyond this time, in the two experimental conditions, we note the total disappearance of these bands after 48 hours. Beyond 48 hours, by chemical analysis the atomic ratio Ca / P remains practically constant and equal to 1.60 ± 0.01 for salts (NH4) H2PO4 and 1.58 ± 0.01 synthesized from the salts (NH4) H2PO4 within experimental error. Also, the SEM photographs have shown the presence of a phase formed of a needle agglomerate.

Published in	Science Research (Volume 3, Issue 1)
DOI	10.11648/j.sr.20150301.11
Page(s)	1-6
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Synthesis, Hydrothermal, Wet Atmosphere, Calcite, Phosphate Salt, Apatite

References

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APA Style

Rachida Elosrouti, Brahim Sallek, Hassan Chaair, Khalid Digua, Hassan Oudadesse. (2015). Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Science Research, 3(1), 1-6. https://doi.org/10.11648/j.sr.20150301.11

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ACS Style

Rachida Elosrouti; Brahim Sallek; Hassan Chaair; Khalid Digua; Hassan Oudadesse. Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Sci. Res. 2015, 3(1), 1-6. doi: 10.11648/j.sr.20150301.11

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AMA Style

Rachida Elosrouti, Brahim Sallek, Hassan Chaair, Khalid Digua, Hassan Oudadesse. Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Sci Res. 2015;3(1):1-6. doi: 10.11648/j.sr.20150301.11

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@article{10.11648/j.sr.20150301.11,
  author = {Rachida Elosrouti and Brahim Sallek and Hassan Chaair and Khalid Digua and Hassan Oudadesse},
  title = {Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere},
  journal = {Science Research},
  volume = {3},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.sr.20150301.11},
  url = {https://doi.org/10.11648/j.sr.20150301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sr.20150301.11},
  abstract = {Hydroxyapatite (Ca10 (PO4)6 (OH)2, HAP) is widely used as a bone graft substitute, potential carriers of drugs and in the purification of proteins, et could be synthesized artificially by various methods but the hydrothermal method at low temperature, which gives a good crystallinity, is often used. Moreover, several studies have shown that, in the synthesis of calcium phosphate, the nature of the final product may differ depending on the experimental conditions including the value of the initial Ca / P ratio, the nature of the calcium salts used and influence of the residence time of the initial products used in experimental conditions. Thus, in this work, while maintaining the initial Ca / P ratio to a fixed value (1,00 ± 0,01), we followed the behavior of two initial mixtures of a calcium salt and one of two other phosphate salts (di-ammonium hydrogen phosphate and di-ammonium hydrogen phosphate) as a function of residence time in an autoclave at a temperature of 80 °C in a saturated water vapor environment. The characteristics of the final product were carried out by four methods: X-ray diffraction, infrared absorption spectroscopy in the range 400 cm-1 _ 4000 cm-1, chemical analysis, and scanning electron microscopy. The XRD analysis has shown that the products obtained have all an apatite structure. They show the presence, alongside that of apatite, the identifiable stripes of the calcite for the residence times in the experience that are less than 48 hours. Similarly, the infrared absorption spectroscopy for short residence times ranging from 2 hours to 8 am always have shown the presence of the bands specific to the CO32- ions which are fit for calcite and which decrease by increasing the residence time. Beyond this time, in the two experimental conditions, we note the total disappearance of these bands after 48 hours. Beyond 48 hours, by chemical analysis the atomic ratio Ca / P remains practically constant and equal to 1.60 ± 0.01 for salts (NH4) H2PO4 and 1.58 ± 0.01 synthesized from the salts (NH4) H2PO4 within experimental error. Also, the SEM photographs have shown the presence of a phase formed of a needle agglomerate.},
 year = {2015}
}

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TY  - JOUR
T1  - Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere
AU  - Rachida Elosrouti
AU  - Brahim Sallek
AU  - Hassan Chaair
AU  - Khalid Digua
AU  - Hassan Oudadesse
Y1  - 2015/01/26
PY  - 2015
N1  - https://doi.org/10.11648/j.sr.20150301.11
DO  - 10.11648/j.sr.20150301.11
T2  - Science Research
JF  - Science Research
JO  - Science Research
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2329-0927
UR  - https://doi.org/10.11648/j.sr.20150301.11
AB  - Hydroxyapatite (Ca10 (PO4)6 (OH)2, HAP) is widely used as a bone graft substitute, potential carriers of drugs and in the purification of proteins, et could be synthesized artificially by various methods but the hydrothermal method at low temperature, which gives a good crystallinity, is often used. Moreover, several studies have shown that, in the synthesis of calcium phosphate, the nature of the final product may differ depending on the experimental conditions including the value of the initial Ca / P ratio, the nature of the calcium salts used and influence of the residence time of the initial products used in experimental conditions. Thus, in this work, while maintaining the initial Ca / P ratio to a fixed value (1,00 ± 0,01), we followed the behavior of two initial mixtures of a calcium salt and one of two other phosphate salts (di-ammonium hydrogen phosphate and di-ammonium hydrogen phosphate) as a function of residence time in an autoclave at a temperature of 80 °C in a saturated water vapor environment. The characteristics of the final product were carried out by four methods: X-ray diffraction, infrared absorption spectroscopy in the range 400 cm-1 _ 4000 cm-1, chemical analysis, and scanning electron microscopy. The XRD analysis has shown that the products obtained have all an apatite structure. They show the presence, alongside that of apatite, the identifiable stripes of the calcite for the residence times in the experience that are less than 48 hours. Similarly, the infrared absorption spectroscopy for short residence times ranging from 2 hours to 8 am always have shown the presence of the bands specific to the CO32- ions which are fit for calcite and which decrease by increasing the residence time. Beyond this time, in the two experimental conditions, we note the total disappearance of these bands after 48 hours. Beyond 48 hours, by chemical analysis the atomic ratio Ca / P remains practically constant and equal to 1.60 ± 0.01 for salts (NH4) H2PO4 and 1.58 ± 0.01 synthesized from the salts (NH4) H2PO4 within experimental error. Also, the SEM photographs have shown the presence of a phase formed of a needle agglomerate.
VL  - 3
IS  - 1
ER  -

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Author Information

Rachida Elosrouti

Laboratory of Agricultural Resources and Process Engineering, Faculty of Sciences Kenitra, Kenitra, Morocco
Brahim Sallek

Laboratory of Agricultural Resources and Process Engineering, Faculty of Sciences Kenitra, Kenitra, Morocco
Hassan Chaair

Laboratory of processes Engineering, Faculty of Science and Techniques Mohammedia, Mohammedia, Morocco
Khalid Digua

Laboratory of processes Engineering, Faculty of Science and Techniques Mohammedia, Mohammedia, Morocco
Hassan Oudadesse

Laboratory of Materials Science, Faculty of Rennes, Rennes, France

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APA Style

Rachida Elosrouti, Brahim Sallek, Hassan Chaair, Khalid Digua, Hassan Oudadesse. (2015). Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Science Research, 3(1), 1-6. https://doi.org/10.11648/j.sr.20150301.11

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ACS Style

Rachida Elosrouti; Brahim Sallek; Hassan Chaair; Khalid Digua; Hassan Oudadesse. Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Sci. Res. 2015, 3(1), 1-6. doi: 10.11648/j.sr.20150301.11

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AMA Style

Rachida Elosrouti, Brahim Sallek, Hassan Chaair, Khalid Digua, Hassan Oudadesse. Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere. Sci Res. 2015;3(1):1-6. doi: 10.11648/j.sr.20150301.11

Copy | Download

@article{10.11648/j.sr.20150301.11,
  author = {Rachida Elosrouti and Brahim Sallek and Hassan Chaair and Khalid Digua and Hassan Oudadesse},
  title = {Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere},
  journal = {Science Research},
  volume = {3},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.sr.20150301.11},
  url = {https://doi.org/10.11648/j.sr.20150301.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sr.20150301.11},
  abstract = {Hydroxyapatite (Ca10 (PO4)6 (OH)2, HAP) is widely used as a bone graft substitute, potential carriers of drugs and in the purification of proteins, et could be synthesized artificially by various methods but the hydrothermal method at low temperature, which gives a good crystallinity, is often used. Moreover, several studies have shown that, in the synthesis of calcium phosphate, the nature of the final product may differ depending on the experimental conditions including the value of the initial Ca / P ratio, the nature of the calcium salts used and influence of the residence time of the initial products used in experimental conditions. Thus, in this work, while maintaining the initial Ca / P ratio to a fixed value (1,00 ± 0,01), we followed the behavior of two initial mixtures of a calcium salt and one of two other phosphate salts (di-ammonium hydrogen phosphate and di-ammonium hydrogen phosphate) as a function of residence time in an autoclave at a temperature of 80 °C in a saturated water vapor environment. The characteristics of the final product were carried out by four methods: X-ray diffraction, infrared absorption spectroscopy in the range 400 cm-1 _ 4000 cm-1, chemical analysis, and scanning electron microscopy. The XRD analysis has shown that the products obtained have all an apatite structure. They show the presence, alongside that of apatite, the identifiable stripes of the calcite for the residence times in the experience that are less than 48 hours. Similarly, the infrared absorption spectroscopy for short residence times ranging from 2 hours to 8 am always have shown the presence of the bands specific to the CO32- ions which are fit for calcite and which decrease by increasing the residence time. Beyond this time, in the two experimental conditions, we note the total disappearance of these bands after 48 hours. Beyond 48 hours, by chemical analysis the atomic ratio Ca / P remains practically constant and equal to 1.60 ± 0.01 for salts (NH4) H2PO4 and 1.58 ± 0.01 synthesized from the salts (NH4) H2PO4 within experimental error. Also, the SEM photographs have shown the presence of a phase formed of a needle agglomerate.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Influence of the Phosphate Salts Nature on the Synthesis of Apatite in a Wet Atmosphere
AU  - Rachida Elosrouti
AU  - Brahim Sallek
AU  - Hassan Chaair
AU  - Khalid Digua
AU  - Hassan Oudadesse
Y1  - 2015/01/26
PY  - 2015
N1  - https://doi.org/10.11648/j.sr.20150301.11
DO  - 10.11648/j.sr.20150301.11
T2  - Science Research
JF  - Science Research
JO  - Science Research
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2329-0927
UR  - https://doi.org/10.11648/j.sr.20150301.11
AB  - Hydroxyapatite (Ca10 (PO4)6 (OH)2, HAP) is widely used as a bone graft substitute, potential carriers of drugs and in the purification of proteins, et could be synthesized artificially by various methods but the hydrothermal method at low temperature, which gives a good crystallinity, is often used. Moreover, several studies have shown that, in the synthesis of calcium phosphate, the nature of the final product may differ depending on the experimental conditions including the value of the initial Ca / P ratio, the nature of the calcium salts used and influence of the residence time of the initial products used in experimental conditions. Thus, in this work, while maintaining the initial Ca / P ratio to a fixed value (1,00 ± 0,01), we followed the behavior of two initial mixtures of a calcium salt and one of two other phosphate salts (di-ammonium hydrogen phosphate and di-ammonium hydrogen phosphate) as a function of residence time in an autoclave at a temperature of 80 °C in a saturated water vapor environment. The characteristics of the final product were carried out by four methods: X-ray diffraction, infrared absorption spectroscopy in the range 400 cm-1 _ 4000 cm-1, chemical analysis, and scanning electron microscopy. The XRD analysis has shown that the products obtained have all an apatite structure. They show the presence, alongside that of apatite, the identifiable stripes of the calcite for the residence times in the experience that are less than 48 hours. Similarly, the infrared absorption spectroscopy for short residence times ranging from 2 hours to 8 am always have shown the presence of the bands specific to the CO32- ions which are fit for calcite and which decrease by increasing the residence time. Beyond this time, in the two experimental conditions, we note the total disappearance of these bands after 48 hours. Beyond 48 hours, by chemical analysis the atomic ratio Ca / P remains practically constant and equal to 1.60 ± 0.01 for salts (NH4) H2PO4 and 1.58 ± 0.01 synthesized from the salts (NH4) H2PO4 within experimental error. Also, the SEM photographs have shown the presence of a phase formed of a needle agglomerate.
VL  - 3
IS  - 1
ER  -

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