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Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review

Received: 17 July 2017     Accepted: 31 July 2017     Published: 18 September 2017
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Abstract

Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly metal complexes have played an important role in the development of new metal based drugs. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. In this review we have focused on research undertaken over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of isoniazid containing synthetic metal complexes.

Published in Science Journal of Chemistry (Volume 5, Issue 5)
DOI 10.11648/j.sjc.20170505.11
Page(s) 62-70
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Metal Based Drugs, Antibacterial, Antifungal, Anti-Tuberculosis, Anti-Cancer, DNA-Interaction and Anti-Tumor Activity

References
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Cite This Article
  • APA Style

    Md. Saddam Hossain, Md. Abdul Mannan, F. K. Camellia, A. K. B. Zaman, C. M. Zakaria, et al. (2017). Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review. Science Journal of Chemistry, 5(5), 62-70. https://doi.org/10.11648/j.sjc.20170505.11

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    ACS Style

    Md. Saddam Hossain; Md. Abdul Mannan; F. K. Camellia; A. K. B. Zaman; C. M. Zakaria, et al. Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review. Sci. J. Chem. 2017, 5(5), 62-70. doi: 10.11648/j.sjc.20170505.11

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    AMA Style

    Md. Saddam Hossain, Md. Abdul Mannan, F. K. Camellia, A. K. B. Zaman, C. M. Zakaria, et al. Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review. Sci J Chem. 2017;5(5):62-70. doi: 10.11648/j.sjc.20170505.11

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  • @article{10.11648/j.sjc.20170505.11,
      author = {Md. Saddam Hossain and Md. Abdul Mannan and F. K. Camellia and A. K. B. Zaman and C. M. Zakaria and Md. Kudrat-E-Zahan},
      title = {Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review},
      journal = {Science Journal of Chemistry},
      volume = {5},
      number = {5},
      pages = {62-70},
      doi = {10.11648/j.sjc.20170505.11},
      url = {https://doi.org/10.11648/j.sjc.20170505.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20170505.11},
      abstract = {Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly metal complexes have played an important role in the development of new metal based drugs. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. In this review we have focused on research undertaken over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of isoniazid containing synthetic metal complexes.},
     year = {2017}
    }
    

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    T1  - Isoniazid Containing Metal Based Drugs as Potential Antimicrobial Agent: A Short Review
    AU  - Md. Saddam Hossain
    AU  - Md. Abdul Mannan
    AU  - F. K. Camellia
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    AU  - C. M. Zakaria
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    Y1  - 2017/09/18
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    N1  - https://doi.org/10.11648/j.sjc.20170505.11
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    T2  - Science Journal of Chemistry
    JF  - Science Journal of Chemistry
    JO  - Science Journal of Chemistry
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    SN  - 2330-099X
    UR  - https://doi.org/10.11648/j.sjc.20170505.11
    AB  - Antibiotic resistance has been growing at an alarming rate and consequently the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly metal complexes have played an important role in the development of new metal based drugs. A significantly rising interest in the design of metal complexes as drugs and diagnostic agents is currently observed in the area of scientific inquiry, specifically termed medicinal inorganic chemistry. In this review we have focused on research undertaken over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of isoniazid containing synthetic metal complexes.
    VL  - 5
    IS  - 5
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Author Information
  • Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh

  • Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh

  • Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh

  • Department of Dermatology, Barind Medical College and Hospital, Rajshahi, Bangladesh

  • Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh

  • Inorganic Research Laboratory, Department of Chemistry, University of Rajshahi, Rajshahi, Bangladesh

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