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The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules

Received: 13 June 2018     Accepted: 28 June 2018     Published: 23 July 2018
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Abstract

Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.

Published in Modern Chemistry (Volume 6, Issue 2)
DOI 10.11648/j.mc.20180602.11
Page(s) 15-19
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Formula Granule, Danggui, IR, Lab Environment, Discrimination

References
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Cite This Article
  • APA Style

    Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. (2018). The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Modern Chemistry, 6(2), 15-19. https://doi.org/10.11648/j.mc.20180602.11

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    ACS Style

    Bi Xiaodong; Ma Jingmei; Tian Wei; Peng Xinhua; Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod. Chem. 2018, 6(2), 15-19. doi: 10.11648/j.mc.20180602.11

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    AMA Style

    Bi Xiaodong, Ma Jingmei, Tian Wei, Peng Xinhua, Gao Han, et al. The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules. Mod Chem. 2018;6(2):15-19. doi: 10.11648/j.mc.20180602.11

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  • @article{10.11648/j.mc.20180602.11,
      author = {Bi Xiaodong and Ma Jingmei and Tian Wei and Peng Xinhua and Gao Han and Li Junshan and Niu Liying},
      title = {The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules},
      journal = {Modern Chemistry},
      volume = {6},
      number = {2},
      pages = {15-19},
      doi = {10.11648/j.mc.20180602.11},
      url = {https://doi.org/10.11648/j.mc.20180602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.mc.20180602.11},
      abstract = {Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - The Application of Lab Environment as the External Disturbance in the 3-Stage IR Method for the Facile Discrimination of Danggui Formula Granules
    AU  - Bi Xiaodong
    AU  - Ma Jingmei
    AU  - Tian Wei
    AU  - Peng Xinhua
    AU  - Gao Han
    AU  - Li Junshan
    AU  - Niu Liying
    Y1  - 2018/07/23
    PY  - 2018
    N1  - https://doi.org/10.11648/j.mc.20180602.11
    DO  - 10.11648/j.mc.20180602.11
    T2  - Modern Chemistry
    JF  - Modern Chemistry
    JO  - Modern Chemistry
    SP  - 15
    EP  - 19
    PB  - Science Publishing Group
    SN  - 2329-180X
    UR  - https://doi.org/10.11648/j.mc.20180602.11
    AB  - Formula granule (FG), as an improved preparation form of traditional liquid dedoction, is of increasing interest and hence it is necessary to develop facile analytical or discrimination methods. Based on the established 3-Stage IR method, a new external disturbance of lab environment (LE) in which room temperature (RT) is 25-30°C and humidity is 25-30%, is introduced to test its applicability in discrimination of Danggui formula granules from different companies in which the LE is used to affect the prepared KBr pellet to produce enough variations for the 3S-IR method. Firstly, the 2D-spectra and pattern recognition algorithm of principal component analysis (PCA) and hierarchical cluster analysis (HCA) are used to select the analytical basis for 2D-COS IR. Secondly, LE-based 2D-COS IR is used for the discrimination. The newly-established LE-based IR can avoid the complex parts of programmed temperature and sampling in IR instrument, and achieve the discrimination of different Danggui Formula Granules.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Department of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, China

  • Department of Laboratory Center, Hebei University of Chinese Medicine, Shijiazhuang, China

  • Department of Laboratory Center, Hebei University of Chinese Medicine, Shijiazhuang, China

  • Shineway Pharmaceutical Group Ltd, Shijiazhuang, China

  • Shineway Pharmaceutical Group Ltd, Shijiazhuang, China

  • Shineway Pharmaceutical Group Ltd, Shijiazhuang, China

  • Department of Pharmacy, Hebei University of Chinese Medicine, Shijiazhuang, China

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