This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC).
| Published in | International Journal of Pharmacy and Chemistry (Volume 11, Issue 6) |
| DOI | 10.11648/j.ijpc.20251106.12 |
| Page(s) | 119-125 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Antacid, Neutralizing Capacity, Titrimetric, Tablets, pH
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APA Style
Benjuma, A. A., Eshkourfu, R. O., Naji, N. F. A., Al-Rabshi, R. M. (2025). Analytical Study of Some Drug Brands Used to Treat Stomach Acidity. International Journal of Pharmacy and Chemistry, 11(6), 119-125. https://doi.org/10.11648/j.ijpc.20251106.12
ACS Style
Benjuma, A. A.; Eshkourfu, R. O.; Naji, N. F. A.; Al-Rabshi, R. M. Analytical Study of Some Drug Brands Used to Treat Stomach Acidity. Int. J. Pharm. Chem. 2025, 11(6), 119-125. doi: 10.11648/j.ijpc.20251106.12
@article{10.11648/j.ijpc.20251106.12,
author = {Aisha Alfituri Benjuma and Rabia Omar Eshkourfu and Najat Faraj Abu Naji and Ruwaida Muammar Al-Rabshi},
title = {Analytical Study of Some Drug Brands Used to Treat Stomach Acidity},
journal = {International Journal of Pharmacy and Chemistry},
volume = {11},
number = {6},
pages = {119-125},
doi = {10.11648/j.ijpc.20251106.12},
url = {https://doi.org/10.11648/j.ijpc.20251106.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20251106.12},
abstract = {This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC).},
year = {2025}
}
TY - JOUR T1 - Analytical Study of Some Drug Brands Used to Treat Stomach Acidity AU - Aisha Alfituri Benjuma AU - Rabia Omar Eshkourfu AU - Najat Faraj Abu Naji AU - Ruwaida Muammar Al-Rabshi Y1 - 2025/12/24 PY - 2025 N1 - https://doi.org/10.11648/j.ijpc.20251106.12 DO - 10.11648/j.ijpc.20251106.12 T2 - International Journal of Pharmacy and Chemistry JF - International Journal of Pharmacy and Chemistry JO - International Journal of Pharmacy and Chemistry SP - 119 EP - 125 PB - Science Publishing Group SN - 2575-5749 UR - https://doi.org/10.11648/j.ijpc.20251106.12 AB - This study is predicated on the assessment of the acid-neutralizing capacity of five distinct commercial brands of antacid. Antacids are prevalent substances utilized by individuals experiencing heightened gastric acidity, owing to their widespread availability in pharmacies. Consequently, this investigation concentrated on several brands of antacid medications, which function as weak bases that neutralize excess stomach acidity, thereby elevating the pH. The quantity of acid neutralized by each antacid was determined through back titration. The acid-neutralizing capacities of the brands were ranked as follows: A > B > E > D > C. The pH of the acid was measured after being heated to a temperature of 37°C, followed by the addition of the antacid, with a subsequent observation period of five minutes post-addition. The results regarding the impact of the antacids on acid pH were recorded as 6.95 for sample A, 6.74 for sample B, 4.58 for brand C, 1.76 for sample E, and 1.73 for sample D. An analysis of the findings indicates that sample A exhibits the highest neutralizing capacity (NC), whereas sample C demonstrates a significantly lower value of neutralizing capacity (NC). VL - 11 IS - 6 ER -