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A Review of Contemporary Markers of Insulin Resistance

Received: 29 November 2018     Accepted: 2 January 2019     Published: 19 February 2019
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Abstract

Backgrounnd: The era of non-communicable diseases has been here with us for a while. Diabetes mellitus, pre-diabetes, insulin resistance, metabolic syndrome and associated complications; have been the centre of interest for many researchers lately. Insulin resistance (IR) has taken a forefront position in this regard. Aim: Insulin resistance has been implicated in the pathogenesis of many metabolic disorders. It heralds the onset of many of these diseases many years before the clinical signs and symptoms. Method: A thorough literature search was done using internet academic search engines and indexation such Google scholar, hinari, Ebsco, Scorpus, etc. Results: Insulin resistance (IR), an independent risk factor for the development of Type 2 diabetes and metabolic syndrome is assessed by several biomarkers. From the historical perspective till date, the authors assess the implication, connection and relevance from various studies to contemporary scientific breakthroughs in this regard for diagnosis and clinical application of markers of insulin resistance in patient management. Conclusion: It is hoped that with the advancement in medical research, more markers of insulin resistance will be discovered that will help in patient managements.

Published in International Journal of Diabetes and Endocrinology (Volume 4, Issue 1)
DOI 10.11648/j.ijde.20190401.13
Page(s) 13-17
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Insulin Resistance, Markers, Diabetes, Metabolic Syndrome, Diseases

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  • APA Style

    Ekpe Lawson, Onuche Lawrence. (2019). A Review of Contemporary Markers of Insulin Resistance. International Journal of Diabetes and Endocrinology, 4(1), 13-17. https://doi.org/10.11648/j.ijde.20190401.13

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    ACS Style

    Ekpe Lawson; Onuche Lawrence. A Review of Contemporary Markers of Insulin Resistance. Int. J. Diabetes Endocrinol. 2019, 4(1), 13-17. doi: 10.11648/j.ijde.20190401.13

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    AMA Style

    Ekpe Lawson, Onuche Lawrence. A Review of Contemporary Markers of Insulin Resistance. Int J Diabetes Endocrinol. 2019;4(1):13-17. doi: 10.11648/j.ijde.20190401.13

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  • @article{10.11648/j.ijde.20190401.13,
      author = {Ekpe Lawson and Onuche Lawrence},
      title = {A Review of Contemporary Markers of Insulin Resistance},
      journal = {International Journal of Diabetes and Endocrinology},
      volume = {4},
      number = {1},
      pages = {13-17},
      doi = {10.11648/j.ijde.20190401.13},
      url = {https://doi.org/10.11648/j.ijde.20190401.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20190401.13},
      abstract = {Backgrounnd: The era of non-communicable diseases has been here with us for a while. Diabetes mellitus, pre-diabetes, insulin resistance, metabolic syndrome and associated complications; have been the centre of interest for many researchers lately. Insulin resistance (IR) has taken a forefront position in this regard. Aim: Insulin resistance has been implicated in the pathogenesis of many metabolic disorders. It heralds the onset of many of these diseases many years before the clinical signs and symptoms. Method: A thorough literature search was done using internet academic search engines and indexation such Google scholar, hinari, Ebsco, Scorpus, etc. Results: Insulin resistance (IR), an independent risk factor for the development of Type 2 diabetes and metabolic syndrome is assessed by several biomarkers. From the historical perspective till date, the authors assess the implication, connection and relevance from various studies to contemporary scientific breakthroughs in this regard for diagnosis and clinical application of markers of insulin resistance in patient management. Conclusion: It is hoped that with the advancement in medical research, more markers of insulin resistance will be discovered that will help in patient managements.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - A Review of Contemporary Markers of Insulin Resistance
    AU  - Ekpe Lawson
    AU  - Onuche Lawrence
    Y1  - 2019/02/19
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ijde.20190401.13
    DO  - 10.11648/j.ijde.20190401.13
    T2  - International Journal of Diabetes and Endocrinology
    JF  - International Journal of Diabetes and Endocrinology
    JO  - International Journal of Diabetes and Endocrinology
    SP  - 13
    EP  - 17
    PB  - Science Publishing Group
    SN  - 2640-1371
    UR  - https://doi.org/10.11648/j.ijde.20190401.13
    AB  - Backgrounnd: The era of non-communicable diseases has been here with us for a while. Diabetes mellitus, pre-diabetes, insulin resistance, metabolic syndrome and associated complications; have been the centre of interest for many researchers lately. Insulin resistance (IR) has taken a forefront position in this regard. Aim: Insulin resistance has been implicated in the pathogenesis of many metabolic disorders. It heralds the onset of many of these diseases many years before the clinical signs and symptoms. Method: A thorough literature search was done using internet academic search engines and indexation such Google scholar, hinari, Ebsco, Scorpus, etc. Results: Insulin resistance (IR), an independent risk factor for the development of Type 2 diabetes and metabolic syndrome is assessed by several biomarkers. From the historical perspective till date, the authors assess the implication, connection and relevance from various studies to contemporary scientific breakthroughs in this regard for diagnosis and clinical application of markers of insulin resistance in patient management. Conclusion: It is hoped that with the advancement in medical research, more markers of insulin resistance will be discovered that will help in patient managements.
    VL  - 4
    IS  - 1
    ER  - 

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Author Information
  • Department of Chemical Pathology, University of Calabar, Calabar, Nigeria

  • Department of Chemical Pathology, University of Calabar Teaching Hospital, Calabar, Nigeria

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