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Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review

Received: 6 March 2022     Accepted: 25 May 2022     Published: 20 July 2022
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Abstract

Introduction: Extended total nephrectomy (ENT) is the treatment for localized or locally advanced renal cancer with vena cava tumor thrombus. The existence of a vena cava thrombus imposes a vascular surgery time which increases the intraoperative mortality and morbidity. Purpose: the purpose of this clinical case and to evaluate our surgical management of non-metastatic renal cancer with subdiaphragmatic vena cava thrombus. Observation: This was a 63-year-old patient who had presented disabling right low back pain associated with macroscopic haematuria no signs of deglobulization on biological examination. The morphological assessment was carried out using an abdominal computed tomography, which revealed a right kidney tumor classified as T3bN1. A tumor extension assessment by thoracic computed tomography was performed afterwards. There were no remote secondary lesions (M0). After CPR discussion, we performed ENT with lymph node dissection associated with inferior vena cava thrombectomy. The post-operative follow-up had been simple. Controls were carried out at 1 month then every 6 months for 1 year and every year for 5 years. There was no local, loco regional or distant recurrence. Conclusion: Kidney cancer with non-metastatic vena cava thrombus represents a locally advanced form whose surgical management must be well assessed, in terms of the increased risk of perioperative morbidity and mortality.

Published in International Journal of Clinical Urology (Volume 6, Issue 2)
DOI 10.11648/j.ijcu.20220602.11
Page(s) 66-70
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Renal Carcinoma, Venous Thrombus, Extended Total Nephrectomy

References
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[3] Burotto M, Renner A. Nephrectomy in metastatic renal cell carcinoma with venous thrombus: more thrombus equals less benefit? Ann Transl Med. 2019 Sep; 7 (Suppl 6): S186.
[4] Onal B, Simsekoglu MF, Gultekin MH, Demirdag C, Citgez S, Erozenci A. Clinical outcomes of radical surgery in patients with renal carcinoma and associated venous thrombosis: Single-centre experience in a tertiary care institution. Int J Clin Pract. 2021 Apr; 75 (4): e13811.
[5] Zhang Y, Tian X, Bi H, Hong P, Liu Z, Yan Y, Liu C, Ma L. Oncologic Outcomes of Renal Cell Carcinoma Patients Undergoing Radical Nephrectomy and Venous Thrombectomy: Prospective Follow-Up from a Single Center. J Oncol. 2022 Mar 17; 2022: 9191659.
[6] Ueki H, Terakawa T, Ueno Y, Sofue K, Horii S, Okamura Y, Bando Y, Hara T, Furukawa J, Harada K, Hinata N, Nakano Y, Murakami T, Fujisawa M. Efficacy of preoperative cine magnetic resonance imaging in evaluation of adhesion of renal cancer thrombus to inferior vena cava wall. J Vasc Surg Venous Lymphat Disord. 2022 Mar 18: S2213-333X (22)00101-9.
[7] Nini A, Muttin F, Cianflone F, Carenzi C, Luciano R, Catena M, Larcher A, Salvioni M, Cazzaniga W, Pederzoli F, Matloob R, Colombo R, Paganelli M, Salonia A, Briganti A, Doglioni C, Zangrillo A, DE Cobelli F, Rigatti P, Freschi M, Cornero G, Nicoletti R, Aldrighetti L, Montorsi F, Capitanio U, Bertini R. Perioperative and oncologic outcomes of open radical nephrectomy and inferior vena cava thrombectomy with liver mobilization and Pringle maneuver for Mayo III level tumor thrombus: single institution experience. Minerva Urol Nephrol. 2021 Dec; 73 (6): 746-753.
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  • APA Style

    Smith Giscard Olagui, Mariette Nsa Bidzo, Ulrich Davy Ngabou, Ernest Belembaogo. (2022). Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review. International Journal of Clinical Urology, 6(2), 66-70. https://doi.org/10.11648/j.ijcu.20220602.11

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    ACS Style

    Smith Giscard Olagui; Mariette Nsa Bidzo; Ulrich Davy Ngabou; Ernest Belembaogo. Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review. Int. J. Clin. Urol. 2022, 6(2), 66-70. doi: 10.11648/j.ijcu.20220602.11

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    AMA Style

    Smith Giscard Olagui, Mariette Nsa Bidzo, Ulrich Davy Ngabou, Ernest Belembaogo. Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review. Int J Clin Urol. 2022;6(2):66-70. doi: 10.11648/j.ijcu.20220602.11

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  • @article{10.11648/j.ijcu.20220602.11,
      author = {Smith Giscard Olagui and Mariette Nsa Bidzo and Ulrich Davy Ngabou and Ernest Belembaogo},
      title = {Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review},
      journal = {International Journal of Clinical Urology},
      volume = {6},
      number = {2},
      pages = {66-70},
      doi = {10.11648/j.ijcu.20220602.11},
      url = {https://doi.org/10.11648/j.ijcu.20220602.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220602.11},
      abstract = {Introduction: Extended total nephrectomy (ENT) is the treatment for localized or locally advanced renal cancer with vena cava tumor thrombus. The existence of a vena cava thrombus imposes a vascular surgery time which increases the intraoperative mortality and morbidity. Purpose: the purpose of this clinical case and to evaluate our surgical management of non-metastatic renal cancer with subdiaphragmatic vena cava thrombus. Observation: This was a 63-year-old patient who had presented disabling right low back pain associated with macroscopic haematuria no signs of deglobulization on biological examination. The morphological assessment was carried out using an abdominal computed tomography, which revealed a right kidney tumor classified as T3bN1. A tumor extension assessment by thoracic computed tomography was performed afterwards. There were no remote secondary lesions (M0). After CPR discussion, we performed ENT with lymph node dissection associated with inferior vena cava thrombectomy. The post-operative follow-up had been simple. Controls were carried out at 1 month then every 6 months for 1 year and every year for 5 years. There was no local, loco regional or distant recurrence. Conclusion: Kidney cancer with non-metastatic vena cava thrombus represents a locally advanced form whose surgical management must be well assessed, in terms of the increased risk of perioperative morbidity and mortality.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Nephrectomy for No Metastatic Renal Cell Carcinoma with Venous Tumor Thrombus About One Case and Literature Review
    AU  - Smith Giscard Olagui
    AU  - Mariette Nsa Bidzo
    AU  - Ulrich Davy Ngabou
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    DO  - 10.11648/j.ijcu.20220602.11
    T2  - International Journal of Clinical Urology
    JF  - International Journal of Clinical Urology
    JO  - International Journal of Clinical Urology
    SP  - 66
    EP  - 70
    PB  - Science Publishing Group
    SN  - 2640-1355
    UR  - https://doi.org/10.11648/j.ijcu.20220602.11
    AB  - Introduction: Extended total nephrectomy (ENT) is the treatment for localized or locally advanced renal cancer with vena cava tumor thrombus. The existence of a vena cava thrombus imposes a vascular surgery time which increases the intraoperative mortality and morbidity. Purpose: the purpose of this clinical case and to evaluate our surgical management of non-metastatic renal cancer with subdiaphragmatic vena cava thrombus. Observation: This was a 63-year-old patient who had presented disabling right low back pain associated with macroscopic haematuria no signs of deglobulization on biological examination. The morphological assessment was carried out using an abdominal computed tomography, which revealed a right kidney tumor classified as T3bN1. A tumor extension assessment by thoracic computed tomography was performed afterwards. There were no remote secondary lesions (M0). After CPR discussion, we performed ENT with lymph node dissection associated with inferior vena cava thrombectomy. The post-operative follow-up had been simple. Controls were carried out at 1 month then every 6 months for 1 year and every year for 5 years. There was no local, loco regional or distant recurrence. Conclusion: Kidney cancer with non-metastatic vena cava thrombus represents a locally advanced form whose surgical management must be well assessed, in terms of the increased risk of perioperative morbidity and mortality.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Urology and Visceral Service, Military Instruction of Omar Bongo Ondimba Hospital, Faculty of Medicine, Urology Department University of Health Sciences, Libreville, Gabon

  • Urology Department, Military Instruction of Omar Bongo Ondimba Hospital, Faculty of Medicine, Urology Department University of Health Sciences, Libreville, Gabon

  • Vascular Department, Military Instruction of Omar Bongo Ondimba Hospital, Vascular Department, Faculty of Medicine, University of Health Sciences, Libreville, Gabon

  • Oncology Department, Cancer Institute of Libreville (ICL), Faculty of Medicine, University of Health Sciences, Libreville, Gabon

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