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Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center

Received: 9 November 2023     Accepted: 24 November 2023     Published: 6 December 2023
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Abstract

Second cancer frequently diagnosed in men; prostate cancer is responsible for high mortality. His prognosis has benefited from significant technical improvements. Determining prognostic factors in prostate cancer is an integral part of the therapeutic decision-making process. The aim of this study was to determine the prognostic factors of prostate cancer in the cancer department of University Hospital of Brazzaville in Congo. This was a retrospective descriptive study, which took place from 1 January 2016 to 31 December 2020, in the cancer department of the University Hospital of Brazzaville in Congo. During the study period, 118 files were retained. The survival curves were realized according to the Kaplan-Meier model, and the statistical comparison according to the Log-Rank model. The significance threshold was set at 5%. The results found that mean age was 68 ± 7.74 years. Low urinary tract symptoms accounted for 68.64% of the discovery circumstances. The Initial PSA was greater than 100 ng/ml in 65.25% of patients. Metastases were found in 95.76% of patients. Overall survival at 3 years was 15%. Survival differed significantly by age (p = 0.0017); WHO performance status (p = 0.0000); clinical stage (p = 0.0000) and metastatic site (p = 0.0022). Finally, the incidence of prostate cancer is increasing worldwide, hence the interest of defining a screening strategy, allowing to institute management with better results.

Published in International Journal of Clinical Oncology and Cancer Research (Volume 8, Issue 4)
DOI 10.11648/j.ijcocr.20230804.13
Page(s) 94-100
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Prostate Cancer, Prognostic Factors, Brazzaville

References
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[2] Tengue K, Kpatcha T, Botcho G, Leloua E, Amavi A, Sikpa K, et al. Profil épidémiologique, diagnostique, thérapeutique et évolutif du cancer de la prostate au Togo. Afr J Urol. 3 juin 2016; 22 (2): 76-82.
[3] Hounnasso P, Avakoudjo J, Aouagbe Behanzin H. Aspects diagnostiques du cancer de la prostate dans le service d’urologie du CNHU-HKM Cotonou. Rev Afr Urol Androl. 2 juill 2015; 1 (4): 193-6.
[4] Xylinas E, Peyromaure M. Cancer de la prostate: traitements. In: EMC- Cancérologie. Paris: Elsevier Masson; 2020. p. 1-19.
[5] Fizazi K, Irani J, Arfi-Rouche J, Chapet O. Tumeurs de la prostate. In: Collège National des Enseignants en Cancérologie. 2ème. Paris: MED-LINE; 2019. p. 349-71.
[6] Yahaya J, Okecha T, Odida M, Wabinga H. Prognostic Factors for Overall Survival of Patients with Prostate Cancer in Kyadondo County, Uganda. Prostate Cancer. 27 janv 2020; 2020 (1): 1-9.
[7] Mbey PM, Mukuku O, Arung WK, Tengu GK, Amisi NL, Kyabu VK, et al. Clinical, Histopathological, and Prognostic Characteristics of Patients with Prostate Cancer in Lubumbashi, Democratic Republic of Congo. Prostate Cancer. 10 déc 2020; 2020: e5286929.
[8] Fournier G, Valeri A, Mangin P, Cussenot O. Cancer de la prostate. Épidémiologie. Facteurs de risques. Anatomopathologie. In: EMC- Cancérologie. Elsevier Masson; 2020. p. 1-13.
[9] Cussenot O, Teillac P. Le cancer de la prostate. Paris: John Libbey Eurotext; 2000. 156 p. (Pathologie, sciences, formation).
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[11] Rozet F, Mongiat-Artus P, Hennequin C, Beauval JB, Beuzeboc P, Cormier L, et al. Recommandations françaises du Comité de cancérologie de l’AFU – actualisation 2020–2022 : cancer de la prostate. Prog En Urol. nov 2020; 30 (12S): S136-251.
[12] Kirakoya B, Hounnasso PP, Pare AK, Mustapha AB, Zango B. Clinico-pathological features of prostate cancer at the university hospital Yalgado Ouedraogo, Ouagadougou, Burkina Faso. J West Afr Coll Surg. déc 2014; 4 (4): 70-81.
[13] Engbang JPN, Sala B, Moby H, Ligan Y, Djimeli BD, Simo G, et al. Epidemiomorphology of Prostate Cancer in Cameroon: About 1047 Cases. J Cancer Tumor Int. 25 nov 2017; 6 (3): 1-8.
[14] Richard TS, Ahmadou M, Hervé NKA, Faustin SEP, Myriam BE, Franklin DS, et al. Prostate Cancer Characteristics and Associated Factors in Northern Cameroon. J Cancer Ther. 12 mai 2021; 12 (5): 289-301.
[15] Cassell A, Yunusa B, Jalloh M, Ndoye M, Mbodji M, Diallo A, et al. Management of Advanced and Metastatic Prostate Cancer: A Need for a Sub-Saharan Guideline. J Oncol. 5 déc 2019; 2019 (2): 1-10.
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Cite This Article
  • APA Style

    Hierrhum Aboubacar, B., Nina Assanatou Jumelle, Z., Valérie, O., Epala Brice Aymard, N., Malanda Judith, N., et al. (2023). Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center. International Journal of Clinical Oncology and Cancer Research, 8(4), 94-100. https://doi.org/10.11648/j.ijcocr.20230804.13

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    ACS Style

    Hierrhum Aboubacar, B.; Nina Assanatou Jumelle, Z.; Valérie, O.; Epala Brice Aymard, N.; Malanda Judith, N., et al. Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center. Int. J. Clin. Oncol. Cancer Res. 2023, 8(4), 94-100. doi: 10.11648/j.ijcocr.20230804.13

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    AMA Style

    Hierrhum Aboubacar B, Nina Assanatou Jumelle Z, Valérie O, Epala Brice Aymard N, Malanda Judith N, et al. Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center. Int J Clin Oncol Cancer Res. 2023;8(4):94-100. doi: 10.11648/j.ijcocr.20230804.13

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  • @article{10.11648/j.ijcocr.20230804.13,
      author = {Bambara Hierrhum Aboubacar and Zerbo Nina Assanatou Jumelle and Odero-Marah Valérie and Nkoua Epala Brice Aymard and Nsonde Malanda Judith and Nkoua-Mbon Jean-Bernard},
      title = {Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {8},
      number = {4},
      pages = {94-100},
      doi = {10.11648/j.ijcocr.20230804.13},
      url = {https://doi.org/10.11648/j.ijcocr.20230804.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20230804.13},
      abstract = {Second cancer frequently diagnosed in men; prostate cancer is responsible for high mortality. His prognosis has benefited from significant technical improvements. Determining prognostic factors in prostate cancer is an integral part of the therapeutic decision-making process. The aim of this study was to determine the prognostic factors of prostate cancer in the cancer department of University Hospital of Brazzaville in Congo. This was a retrospective descriptive study, which took place from 1 January 2016 to 31 December 2020, in the cancer department of the University Hospital of Brazzaville in Congo. During the study period, 118 files were retained. The survival curves were realized according to the Kaplan-Meier model, and the statistical comparison according to the Log-Rank model. The significance threshold was set at 5%. The results found that mean age was 68 ± 7.74 years. Low urinary tract symptoms accounted for 68.64% of the discovery circumstances. The Initial PSA was greater than 100 ng/ml in 65.25% of patients. Metastases were found in 95.76% of patients. Overall survival at 3 years was 15%. Survival differed significantly by age (p = 0.0017); WHO performance status (p = 0.0000); clinical stage (p = 0.0000) and metastatic site (p = 0.0022). Finally, the incidence of prostate cancer is increasing worldwide, hence the interest of defining a screening strategy, allowing to institute management with better results.
    },
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Prognostic Factors for Prostate Cancer at the Brazzaville University Hospital Center
    AU  - Bambara Hierrhum Aboubacar
    AU  - Zerbo Nina Assanatou Jumelle
    AU  - Odero-Marah Valérie
    AU  - Nkoua Epala Brice Aymard
    AU  - Nsonde Malanda Judith
    AU  - Nkoua-Mbon Jean-Bernard
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    DO  - 10.11648/j.ijcocr.20230804.13
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
    SP  - 94
    EP  - 100
    PB  - Science Publishing Group
    SN  - 2578-9511
    UR  - https://doi.org/10.11648/j.ijcocr.20230804.13
    AB  - Second cancer frequently diagnosed in men; prostate cancer is responsible for high mortality. His prognosis has benefited from significant technical improvements. Determining prognostic factors in prostate cancer is an integral part of the therapeutic decision-making process. The aim of this study was to determine the prognostic factors of prostate cancer in the cancer department of University Hospital of Brazzaville in Congo. This was a retrospective descriptive study, which took place from 1 January 2016 to 31 December 2020, in the cancer department of the University Hospital of Brazzaville in Congo. During the study period, 118 files were retained. The survival curves were realized according to the Kaplan-Meier model, and the statistical comparison according to the Log-Rank model. The significance threshold was set at 5%. The results found that mean age was 68 ± 7.74 years. Low urinary tract symptoms accounted for 68.64% of the discovery circumstances. The Initial PSA was greater than 100 ng/ml in 65.25% of patients. Metastases were found in 95.76% of patients. Overall survival at 3 years was 15%. Survival differed significantly by age (p = 0.0017); WHO performance status (p = 0.0000); clinical stage (p = 0.0000) and metastatic site (p = 0.0022). Finally, the incidence of prostate cancer is increasing worldwide, hence the interest of defining a screening strategy, allowing to institute management with better results.
    
    VL  - 8
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Author Information
  • Clinical Hematology Oncology Department, University Teaching Hospital Bogodogo, Ouagadougou, Burkina Faso; Health Sciences Training and Research Unit Department (UFR/SDS), Joseph KI-ZERBO University, Ouagadougou, Burkina Faso

  • Clinical Hematology Oncology Department, University Teaching Hospital Bogodogo, Ouagadougou, Burkina Faso

  • Center for Urban Heath Disparities Research and Innovation, Department of Biology, Morgan State University, Baltimore, United States of America (USA)

  • Clinical Oncology Department, University Teaching Hospital of Brazzaville, Brazzaville, Congo

  • Clinical Oncology Department, University Teaching Hospital of Brazzaville, Brazzaville, Congo

  • Clinical Oncology Department, University Teaching Hospital of Brazzaville, Brazzaville, Congo

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