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Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015

Received: 27 August 2017     Accepted: 21 September 2017     Published: 3 January 2018
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Abstract

Often tumors in the African setting are described aggressive with high grading status. There is no national cancer registry nor suitable data on breast cancer in DRC. Better knowledge of this entity can improve its management. To demonstrate the clinical and pathological profile of breast cancer in Kinshasa and Lubumbashi (DR Congo). Cross-sectional study of 86 patients were included for clinical and pathological in the Cities of Lubumbashi and Kinshasa from 2014-2016. All cases were women with histological invasive breast carcinoma. Parameters studied were: age of patients at diagnosis, morphological type [33], grade [23] of tumor, tumor necrosis and Nottingham score. Statistical analysis used SPSS program and Pearson Khi-square test. From January 2014 to September 2016, 86 cases were reviewed. The average age of patients at diagnosis was 47.8 ± 12.1 years. In 74% of cases, patients were presented at stage T3 or T4. The average size of tumors was 6.6 ± 2.7 cm. Invasive Ductular carcinoma was found in 97.2% of cases. Grade 3 tumors were found in 54.7% and grade 1 in 4.7%. Tumor necrosis was present in 30.2% of biopsies. The Nottingham score higher than 5.4 was found in 62.8%. All the patients were treated by supra-radical mastectomy. Lymph nodes were numbered in each case. Prognosis of breast cancers is poor in Lubumbashi and Kinshasa University Hospitals for tumors are diagnosed later. To improve breast cancer management, tumor must be diagnosed earlier. Perception of this pathology and its correct assessment are important for better taking care in the Democratic Republic of the Congo.

Published in International Journal of Clinical Oncology and Cancer Research (Volume 2, Issue 6)
DOI 10.11648/j.ijcocr.20170206.13
Page(s) 141-148
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

Breast Carcinoma, Clinico-Pathological Evaluation, Prognosis

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Cite This Article
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    Nday Guy, Kabamba Michel, Mukalay Abdon, Tshilombo François, Odimba Etienne, et al. (2018). Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015. International Journal of Clinical Oncology and Cancer Research, 2(6), 141-148. https://doi.org/10.11648/j.ijcocr.20170206.13

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    ACS Style

    Nday Guy; Kabamba Michel; Mukalay Abdon; Tshilombo François; Odimba Etienne, et al. Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015. Int. J. Clin. Oncol. Cancer Res. 2018, 2(6), 141-148. doi: 10.11648/j.ijcocr.20170206.13

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    AMA Style

    Nday Guy, Kabamba Michel, Mukalay Abdon, Tshilombo François, Odimba Etienne, et al. Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015. Int J Clin Oncol Cancer Res. 2018;2(6):141-148. doi: 10.11648/j.ijcocr.20170206.13

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  • @article{10.11648/j.ijcocr.20170206.13,
      author = {Nday Guy and Kabamba Michel and Mukalay Abdon and Tshilombo François and Odimba Etienne and Lebwaz Bienvenu and Kalenga Prospère and Ilunga Julien},
      title = {Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015},
      journal = {International Journal of Clinical Oncology and Cancer Research},
      volume = {2},
      number = {6},
      pages = {141-148},
      doi = {10.11648/j.ijcocr.20170206.13},
      url = {https://doi.org/10.11648/j.ijcocr.20170206.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcocr.20170206.13},
      abstract = {Often tumors in the African setting are described aggressive with high grading status. There is no national cancer registry nor suitable data on breast cancer in DRC. Better knowledge of this entity can improve its management. To demonstrate the clinical and pathological profile of breast cancer in Kinshasa and Lubumbashi (DR Congo). Cross-sectional study of 86 patients were included for clinical and pathological in the Cities of Lubumbashi and Kinshasa from 2014-2016. All cases were women with histological invasive breast carcinoma. Parameters studied were: age of patients at diagnosis, morphological type [33], grade [23] of tumor, tumor necrosis and Nottingham score. Statistical analysis used SPSS program and Pearson Khi-square test. From January 2014 to September 2016, 86 cases were reviewed. The average age of patients at diagnosis was 47.8 ± 12.1 years. In 74% of cases, patients were presented at stage T3 or T4. The average size of tumors was 6.6 ± 2.7 cm. Invasive Ductular carcinoma was found in 97.2% of cases. Grade 3 tumors were found in 54.7% and grade 1 in 4.7%. Tumor necrosis was present in 30.2% of biopsies. The Nottingham score higher than 5.4 was found in 62.8%. All the patients were treated by supra-radical mastectomy. Lymph nodes were numbered in each case. Prognosis of breast cancers is poor in Lubumbashi and Kinshasa University Hospitals for tumors are diagnosed later. To improve breast cancer management, tumor must be diagnosed earlier. Perception of this pathology and its correct assessment are important for better taking care in the Democratic Republic of the Congo.},
     year = {2018}
    }
    

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  • TY  - JOUR
    T1  - Breast Cancer: Clinical and Pathological Study at Lubumbashi and Kinshasa University Hospitals in the Democratic Republic of the Congo from 2014 to 2015
    AU  - Nday Guy
    AU  - Kabamba Michel
    AU  - Mukalay Abdon
    AU  - Tshilombo François
    AU  - Odimba Etienne
    AU  - Lebwaz Bienvenu
    AU  - Kalenga Prospère
    AU  - Ilunga Julien
    Y1  - 2018/01/03
    PY  - 2018
    N1  - https://doi.org/10.11648/j.ijcocr.20170206.13
    DO  - 10.11648/j.ijcocr.20170206.13
    T2  - International Journal of Clinical Oncology and Cancer Research
    JF  - International Journal of Clinical Oncology and Cancer Research
    JO  - International Journal of Clinical Oncology and Cancer Research
    SP  - 141
    EP  - 148
    PB  - Science Publishing Group
    SN  - 2578-9511
    UR  - https://doi.org/10.11648/j.ijcocr.20170206.13
    AB  - Often tumors in the African setting are described aggressive with high grading status. There is no national cancer registry nor suitable data on breast cancer in DRC. Better knowledge of this entity can improve its management. To demonstrate the clinical and pathological profile of breast cancer in Kinshasa and Lubumbashi (DR Congo). Cross-sectional study of 86 patients were included for clinical and pathological in the Cities of Lubumbashi and Kinshasa from 2014-2016. All cases were women with histological invasive breast carcinoma. Parameters studied were: age of patients at diagnosis, morphological type [33], grade [23] of tumor, tumor necrosis and Nottingham score. Statistical analysis used SPSS program and Pearson Khi-square test. From January 2014 to September 2016, 86 cases were reviewed. The average age of patients at diagnosis was 47.8 ± 12.1 years. In 74% of cases, patients were presented at stage T3 or T4. The average size of tumors was 6.6 ± 2.7 cm. Invasive Ductular carcinoma was found in 97.2% of cases. Grade 3 tumors were found in 54.7% and grade 1 in 4.7%. Tumor necrosis was present in 30.2% of biopsies. The Nottingham score higher than 5.4 was found in 62.8%. All the patients were treated by supra-radical mastectomy. Lymph nodes were numbered in each case. Prognosis of breast cancers is poor in Lubumbashi and Kinshasa University Hospitals for tumors are diagnosed later. To improve breast cancer management, tumor must be diagnosed earlier. Perception of this pathology and its correct assessment are important for better taking care in the Democratic Republic of the Congo.
    VL  - 2
    IS  - 6
    ER  - 

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Author Information
  • Surgery Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Department of Public Health, University of Kamina, Kamina, Democratic Republic of Congo

  • Clinical Epidemiology Unit and Tropical Pathologies, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Surgery Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Pathology Department, University Hospital of Kinshasa, University of Kinshasa, Kamina, Democratic Republic of Congo

  • Department of Obstetrics and Gynecology, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

  • Pathology Department, University Hospital of Lubumbashi, University of Lubumbashi, Lubumbashi, Democratic Republic of Congo

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