Cancer Research Journal

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Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study

Received: Aug. 29, 2023    Accepted: Sep. 13, 2023    Published: Sep. 27, 2023
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Abstract

Objective: To describe the epidemiological, clinical, therapeutic and prognostic aspects of breast cancer in women aged 40 years and younger. Material and methods: This was are retrospective descriptive cohort of 128 months, from April 11, 2007, to December 31, 2017; including patients aged 40 years and younger who had been treated and followed up for breast cancer at the surgical oncology unit of the Donka CHU National Hospital in Conakry. Results: A total of 184 patients were enrolled in this study. The mean age was 33.5 ± 5.4 years. A family history of breast cancer was found in 16 (8.69%) patients. The presence of nodule was the most frequent symptom (91.3%). It was an infiltrating ductal carcinoma in 67.3% of patients. Stages IIIB, IV, and IIIA were the most frequent with 40.2%, 23.3% and 9.2% respectively. Mastectomy was radical in 93.9% of the cases. The associated treatments were chemotherapy (86.4%), radiotherapy (15.7%) and hormone therapy (2.7%). We recorded 79 (42.9%) deaths. Overall survival at 5 years was 31%. Conclusion: Breast cancer in young women remains serious because of its high frequency, more progressive form, and poorer prognosis compared with that of older patients.

DOI 10.11648/j.crj.20231103.16
Published in Cancer Research Journal ( Volume 11, Issue 3, September 2023 )
Page(s) 116-121
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Breast Cancer, Young Women, Conakry

References
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    Malick Bah, Keita Mamady, Touré Alhassane Ismael, Cisse Kalil, Souare Mamadou Bobo, et al. (2023). Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study. Cancer Research Journal, 11(3), 116-121. https://doi.org/10.11648/j.crj.20231103.16

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    ACS Style

    Malick Bah; Keita Mamady; Touré Alhassane Ismael; Cisse Kalil; Souare Mamadou Bobo, et al. Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study. Cancer Res. J. 2023, 11(3), 116-121. doi: 10.11648/j.crj.20231103.16

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    AMA Style

    Malick Bah, Keita Mamady, Touré Alhassane Ismael, Cisse Kalil, Souare Mamadou Bobo, et al. Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study. Cancer Res J. 2023;11(3):116-121. doi: 10.11648/j.crj.20231103.16

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  • @article{10.11648/j.crj.20231103.16,
      author = {Malick Bah and Keita Mamady and Touré Alhassane Ismael and Cisse Kalil and Souare Mamadou Bobo and Conde Ibrahima Kalil and Traore Bangaly},
      title = {Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study},
      journal = {Cancer Research Journal},
      volume = {11},
      number = {3},
      pages = {116-121},
      doi = {10.11648/j.crj.20231103.16},
      url = {https://doi.org/10.11648/j.crj.20231103.16},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.crj.20231103.16},
      abstract = {Objective: To describe the epidemiological, clinical, therapeutic and prognostic aspects of breast cancer in women aged 40 years and younger. Material and methods: This was are retrospective descriptive cohort of 128 months, from April 11, 2007, to December 31, 2017; including patients aged 40 years and younger who had been treated and followed up for breast cancer at the surgical oncology unit of the Donka CHU National Hospital in Conakry. Results: A total of 184 patients were enrolled in this study. The mean age was 33.5 ± 5.4 years. A family history of breast cancer was found in 16 (8.69%) patients. The presence of nodule was the most frequent symptom (91.3%). It was an infiltrating ductal carcinoma in 67.3% of patients. Stages IIIB, IV, and IIIA were the most frequent with 40.2%, 23.3% and 9.2% respectively. Mastectomy was radical in 93.9% of the cases. The associated treatments were chemotherapy (86.4%), radiotherapy (15.7%) and hormone therapy (2.7%). We recorded 79 (42.9%) deaths. Overall survival at 5 years was 31%. Conclusion: Breast cancer in young women remains serious because of its high frequency, more progressive form, and poorer prognosis compared with that of older patients.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Breast Cancer in Women Under 40 Years of Age Surgical Oncology Unit of Donka National Hospital a Retrospective Cohort Study
    AU  - Malick Bah
    AU  - Keita Mamady
    AU  - Touré Alhassane Ismael
    AU  - Cisse Kalil
    AU  - Souare Mamadou Bobo
    AU  - Conde Ibrahima Kalil
    AU  - Traore Bangaly
    Y1  - 2023/09/27
    PY  - 2023
    N1  - https://doi.org/10.11648/j.crj.20231103.16
    DO  - 10.11648/j.crj.20231103.16
    T2  - Cancer Research Journal
    JF  - Cancer Research Journal
    JO  - Cancer Research Journal
    SP  - 116
    EP  - 121
    PB  - Science Publishing Group
    SN  - 2330-8214
    UR  - https://doi.org/10.11648/j.crj.20231103.16
    AB  - Objective: To describe the epidemiological, clinical, therapeutic and prognostic aspects of breast cancer in women aged 40 years and younger. Material and methods: This was are retrospective descriptive cohort of 128 months, from April 11, 2007, to December 31, 2017; including patients aged 40 years and younger who had been treated and followed up for breast cancer at the surgical oncology unit of the Donka CHU National Hospital in Conakry. Results: A total of 184 patients were enrolled in this study. The mean age was 33.5 ± 5.4 years. A family history of breast cancer was found in 16 (8.69%) patients. The presence of nodule was the most frequent symptom (91.3%). It was an infiltrating ductal carcinoma in 67.3% of patients. Stages IIIB, IV, and IIIA were the most frequent with 40.2%, 23.3% and 9.2% respectively. Mastectomy was radical in 93.9% of the cases. The associated treatments were chemotherapy (86.4%), radiotherapy (15.7%) and hormone therapy (2.7%). We recorded 79 (42.9%) deaths. Overall survival at 5 years was 31%. Conclusion: Breast cancer in young women remains serious because of its high frequency, more progressive form, and poorer prognosis compared with that of older patients.
    VL  - 11
    IS  - 3
    ER  - 

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Author Information
  • Donka Surgical Oncology Unit, Faculty of Health Sciences and Technology, Gamal Abdel Nasser University, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Surgical Oncology Unit, Donka National Hospital, Conakry, Guinea

  • Section