Clinical Neurology and Neuroscience

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Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt

Received: Aug. 20, 2023    Accepted: Sep. 08, 2023    Published: Sep. 25, 2023
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Abstract

Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.

DOI 10.11648/j.cnn.20230703.12
Published in Clinical Neurology and Neuroscience ( Volume 7, Issue 3, September 2023 )
Page(s) 51-55
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

INPH, CSF, INPHGS, MRI, V-P shunt, MMSE, MOCA, AD

References
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Cite This Article
  • APA Style

    Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. (2023). Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clinical Neurology and Neuroscience, 7(3), 51-55. https://doi.org/10.11648/j.cnn.20230703.12

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    ACS Style

    Mohamed Hamdy Ismail; Ahmed Ragab; Hossam Mohamed Refat; Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin. Neurol. Neurosci. 2023, 7(3), 51-55. doi: 10.11648/j.cnn.20230703.12

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    AMA Style

    Mohamed Hamdy Ismail, Ahmed Ragab, Hossam Mohamed Refat, Hassan Abaza. Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt. Clin Neurol Neurosci. 2023;7(3):51-55. doi: 10.11648/j.cnn.20230703.12

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  • @article{10.11648/j.cnn.20230703.12,
      author = {Mohamed Hamdy Ismail and Ahmed Ragab and Hossam Mohamed Refat and Hassan Abaza},
      title = {Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt},
      journal = {Clinical Neurology and Neuroscience},
      volume = {7},
      number = {3},
      pages = {51-55},
      doi = {10.11648/j.cnn.20230703.12},
      url = {https://doi.org/10.11648/j.cnn.20230703.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.cnn.20230703.12},
      abstract = {Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.},
     year = {2023}
    }
    

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  • TY  - JOUR
    T1  - Cognitive Functions in Patients with Idiopathic Normal Pressure Hydrocephalus Before and After Ventriculoperitoneal Shunt
    AU  - Mohamed Hamdy Ismail
    AU  - Ahmed Ragab
    AU  - Hossam Mohamed Refat
    AU  - Hassan Abaza
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    DO  - 10.11648/j.cnn.20230703.12
    T2  - Clinical Neurology and Neuroscience
    JF  - Clinical Neurology and Neuroscience
    JO  - Clinical Neurology and Neuroscience
    SP  - 51
    EP  - 55
    PB  - Science Publishing Group
    SN  - 2578-8930
    UR  - https://doi.org/10.11648/j.cnn.20230703.12
    AB  - Background: Clinical manifestations of idiopathic normal pressure hydrocephalus [iNPH] involve dementia, urinary incontinence and gait disturbance. Idiopathic normal pressure hydrocephalus treatment for short- and long-term improvement and maintenance of gait and also cognitive function is essential for reducing the caregiving burden on families and society. Methods: this study was done on 41participants with a diagnosis of iNPH, subjected to detailed medical and neurological history taking and neuropsychological assessment for cognitive functions before and after ventriculoperitoneal shunt operation. Results: After CSF (cerebro-spinal fluid) shunting, around 80.5% of cases with idiopathic normal pressure hydrocephalus demonstrated enhanced and sustained cognitive function for at least 1 year post-operatively and our study revealed that younger age and less severe idiopathic normal pressure hydrocephalus led to a good long-term prognosis of cognitive function. Conclusions: Individuals with idiopathic normal pressure hydrocephalus experienced improved cognitive function 3-12 months after CSF shunt operation, with greater improvement seen in younger patients with milder illness. Therefore, early identification and appropriate treatment are crucial for long-term recovery and preservation of cognitive function in idiopathic normal pressure hydrocephalus. Early diagnosis of iNPH followed by CSF Shunt treatment can improve cognitive functions. Long-term evaluations of cognitive functions after V-P (ventriculo peritoneal) shunt operation are recommended.
    VL  - 7
    IS  - 3
    ER  - 

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Author Information
  • Department of Neurology, Faculty of Medicine, Zagazig University, Zagazig, Egypt

  • Department of Neurosurgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt

  • Department of Neurology, Faculty of Medicine, Zagazig University, Zagazig, Egypt

  • Department of Neurosurgery, Faculty of Medicine, Zagazig University, Zagazig, Egypt

  • Section