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Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3

Received: 6 December 2021     Accepted: 27 August 2022     Published: 5 September 2022
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Abstract

It is known from previous works that about a third of men and almost half of women are sensitive to changes in weather conditions. Approximately 65 - 75% of patients with cardiovascular diseases suffer from weather sensitivity. These patients may be dependent on atmospheric variations in temperature and pressure, relative humidity, and geomagnetic activity. In recent years, the dependence f weather-sensitive people on geomagnetic perturbation has been reliably established. The purpose of our research was to find out correlations between Earth and cosmic weather factors and hemodynamics parameters alongside therapy with IATE (prestarium, noliprel) and BRA2 (lozap, Losartan, lorista, blocktran) in elderly patients with arterial hypertension stage 3, degree 3 and influence of terrestrial factor on hypotensive effect. 185 elderly patients with arterial hypertension were examined, including 79 men and 106 women between the ages of 60 to 88. The task: to investigate the results of treatment of elderly patients with hypertensive disease stage 3, degree 3 of IATE and BRA 2 in the gender aspect and to test the effectiveness of the receiving hypotensive therapy alongside meteorological (atmospheric temperature, humidity, atmospheric pressure) and geomagnetic factors (geomagnetic activity expressed by the total planetary Kp-index). It is known that the cardiovascular system parameters are influenced by the parameters of terrestrial and space weather. Despite a large number of studies on the role of fluctuations in weather factors on cardiovascular parameters, this question has not been examined in the gender aspect in elderly patients with hypertensive disease stage 3 degree 3. We demonstrated the influence of changes in atmospheric temperature, air pressure, humidity and Kp-index of geomagnetic activity on heart rate and arterial blood pressure alongside therapy with IATE and BRA2 in elderly women and men, suffering from hypertensive disease stage 3. There were no differences in hypotensive effect of IATE between women and men. But there were differences in hypotensive effect of BRA2 between women and men.

Published in American Journal of Bioscience and Bioengineering (Volume 10, Issue 5)
DOI 10.11648/j.bio.20221005.11
Page(s) 105-108
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Space Weather Factors, Gender Differences, Angiotensin-Transforming Enzyme Inhibitors (IATE), Angiotensin Receptor Blockers 2 (BRA2), Coefficients Correlation, Elderly Patients, Arterial Hypertension

References
[1] Breus T. K. - Influence of cosmic weather on biological rhythms in human//Material of International conference.- Moscow.-2006.-p. 27-30.
[2] Krivchikova L. V. - Gender differences of therapy of elderly patients with hypertension and influence of meteo-geomagnetic factors//Diss. cand. med. science. Moscow., 2015.-130p.
[3] Krivchikova L. V., Zaslavskaya R. M., Tejblum M. M. - Gender differences of hemodynamics in application of angiotensin receptors blockers 2 and angiotensin - transforming enzyme inhibitors in elderly patients with hypertension stage 3. // Materials of International scientific and practical conference., 2014.- v. 26. –p. 64 -74. Czech republic. «Strategic issue of World science».
[4] Savenkov M. P. - Seasonal correction of antihypertensive therapy with taking into account of meteosensibility change. // Material of 12 Russian national congress «Man and drugs».-2009.- p-17-20.
[5] Shcherban E. A. - Influence of meteorological and geomagnetic activity on hemodynamics in patients with arterial hypertension and ischemic heart disease and way of pharmacological defense. // Diss. doct. Moscow.-2013.-295p.
[6] Tihomirov S. - Climate and health. Influence of climate on the health in man. // Med. Journal. -2012.
[7] Tkacheva O. N. - Arterial hypertension in women in postmenopause // Systemic hypertension.-2013.-v. 10.-#3.-p. 98-100.
[8] Zaslavskaya R. M. - Chronopharmacology and chronotherapy // Chronobiology and chronomedicina.-M.-Triada-x.-2000.-97-211p.
[9] Zaslavskaya R. M., Shcherban E. A., Tejblum M. M. - Optimization of therapy of meteosensibility patients with arterial hypertension and ischemic heart disease by use adaptogenes // Monograph.- Medpractika.-M.-Moacow.-2012.-256p.
[10] Zenchenko T. A., Zagareshvily E. V. et al.- Influence of geomagnetic and meteorologic activity on patients with arterial hypertension//j. klinic. Medicina.-2007.-v. 85.-#1.-31-35p.
[11] Zenchenko T. A., Scavuljak A. N. et al.- Characteristics of individual reactions of cardio-vascular sys in health man on change in meteorological factors in wide diapason of temperature//Geophysical processes and biosphere, 2013, -v. 12. -22-44p.
[12] Zenchenko T. A., Breus T. K.-The possible effect of space weather factors on various physiological systems of the human organism // Atmosphere 2021 N 3 -v 12 p. 346.
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[14] Sasonko M. L., Ozheredov V. A., Breus T. K., Ishkov V. N., Klochikhina O. A., Gurfinkel Y. I.-Combined influence of the local atmosphere conditions and space weather on three parameters of 24-h electrocardiogram monitoring //J. International journal of biometeorology. 2019 v. 63 N. 1 p. 93-105.
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    Zaslavskaya Rina Mikhailovna, Kryvchikova Larisa Vladimirovna, Teiblum Michail Mendeleevich. (2022). Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3. American Journal of Bioscience and Bioengineering, 10(5), 105-108. https://doi.org/10.11648/j.bio.20221005.11

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    ACS Style

    Zaslavskaya Rina Mikhailovna; Kryvchikova Larisa Vladimirovna; Teiblum Michail Mendeleevich. Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3. Am. J. BioSci. Bioeng. 2022, 10(5), 105-108. doi: 10.11648/j.bio.20221005.11

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    AMA Style

    Zaslavskaya Rina Mikhailovna, Kryvchikova Larisa Vladimirovna, Teiblum Michail Mendeleevich. Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3. Am J BioSci Bioeng. 2022;10(5):105-108. doi: 10.11648/j.bio.20221005.11

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  • @article{10.11648/j.bio.20221005.11,
      author = {Zaslavskaya Rina Mikhailovna and Kryvchikova Larisa Vladimirovna and Teiblum Michail Mendeleevich},
      title = {Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3},
      journal = {American Journal of Bioscience and Bioengineering},
      volume = {10},
      number = {5},
      pages = {105-108},
      doi = {10.11648/j.bio.20221005.11},
      url = {https://doi.org/10.11648/j.bio.20221005.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20221005.11},
      abstract = {It is known from previous works that about a third of men and almost half of women are sensitive to changes in weather conditions. Approximately 65 - 75% of patients with cardiovascular diseases suffer from weather sensitivity. These patients may be dependent on atmospheric variations in temperature and pressure, relative humidity, and geomagnetic activity. In recent years, the dependence f weather-sensitive people on geomagnetic perturbation has been reliably established. The purpose of our research was to find out correlations between Earth and cosmic weather factors and hemodynamics parameters alongside therapy with IATE (prestarium, noliprel) and BRA2 (lozap, Losartan, lorista, blocktran) in elderly patients with arterial hypertension stage 3, degree 3 and influence of terrestrial factor on hypotensive effect. 185 elderly patients with arterial hypertension were examined, including 79 men and 106 women between the ages of 60 to 88. The task: to investigate the results of treatment of elderly patients with hypertensive disease stage 3, degree 3 of IATE and BRA 2 in the gender aspect and to test the effectiveness of the receiving hypotensive therapy alongside meteorological (atmospheric temperature, humidity, atmospheric pressure) and geomagnetic factors (geomagnetic activity expressed by the total planetary Kp-index). It is known that the cardiovascular system parameters are influenced by the parameters of terrestrial and space weather. Despite a large number of studies on the role of fluctuations in weather factors on cardiovascular parameters, this question has not been examined in the gender aspect in elderly patients with hypertensive disease stage 3 degree 3. We demonstrated the influence of changes in atmospheric temperature, air pressure, humidity and Kp-index of geomagnetic activity on heart rate and arterial blood pressure alongside therapy with IATE and BRA2 in elderly women and men, suffering from hypertensive disease stage 3. There were no differences in hypotensive effect of IATE between women and men. But there were differences in hypotensive effect of BRA2 between women and men.},
     year = {2022}
    }
    

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  • TY  - JOUR
    T1  - Gender Differences in the Influence of Terrestrial and Cosmic Weather on Hypotensive Therapy Effectiveness for Elderly Patients with Arterial Hypertension Stage 3
    AU  - Zaslavskaya Rina Mikhailovna
    AU  - Kryvchikova Larisa Vladimirovna
    AU  - Teiblum Michail Mendeleevich
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    PY  - 2022
    N1  - https://doi.org/10.11648/j.bio.20221005.11
    DO  - 10.11648/j.bio.20221005.11
    T2  - American Journal of Bioscience and Bioengineering
    JF  - American Journal of Bioscience and Bioengineering
    JO  - American Journal of Bioscience and Bioengineering
    SP  - 105
    EP  - 108
    PB  - Science Publishing Group
    SN  - 2328-5893
    UR  - https://doi.org/10.11648/j.bio.20221005.11
    AB  - It is known from previous works that about a third of men and almost half of women are sensitive to changes in weather conditions. Approximately 65 - 75% of patients with cardiovascular diseases suffer from weather sensitivity. These patients may be dependent on atmospheric variations in temperature and pressure, relative humidity, and geomagnetic activity. In recent years, the dependence f weather-sensitive people on geomagnetic perturbation has been reliably established. The purpose of our research was to find out correlations between Earth and cosmic weather factors and hemodynamics parameters alongside therapy with IATE (prestarium, noliprel) and BRA2 (lozap, Losartan, lorista, blocktran) in elderly patients with arterial hypertension stage 3, degree 3 and influence of terrestrial factor on hypotensive effect. 185 elderly patients with arterial hypertension were examined, including 79 men and 106 women between the ages of 60 to 88. The task: to investigate the results of treatment of elderly patients with hypertensive disease stage 3, degree 3 of IATE and BRA 2 in the gender aspect and to test the effectiveness of the receiving hypotensive therapy alongside meteorological (atmospheric temperature, humidity, atmospheric pressure) and geomagnetic factors (geomagnetic activity expressed by the total planetary Kp-index). It is known that the cardiovascular system parameters are influenced by the parameters of terrestrial and space weather. Despite a large number of studies on the role of fluctuations in weather factors on cardiovascular parameters, this question has not been examined in the gender aspect in elderly patients with hypertensive disease stage 3 degree 3. We demonstrated the influence of changes in atmospheric temperature, air pressure, humidity and Kp-index of geomagnetic activity on heart rate and arterial blood pressure alongside therapy with IATE and BRA2 in elderly women and men, suffering from hypertensive disease stage 3. There were no differences in hypotensive effect of IATE between women and men. But there were differences in hypotensive effect of BRA2 between women and men.
    VL  - 10
    IS  - 5
    ER  - 

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Author Information
  • Speace Research Institute the Russian Academy of Sciences, Moscow, Russia

  • The State Budget Health Institution of the Moscow Clinical Research and Practical Center of the Moscow Department of Health, Moscow, Russia

  • Information Management of the Health Insurance Company Solidarity for Life, Moscow, Russia

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