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Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia

Received: 4 October 2017     Accepted: 26 October 2017     Published: 22 November 2017
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Abstract

Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.

Published in American Journal of Bioscience and Bioengineering (Volume 5, Issue 5)
DOI 10.11648/j.bio.20170505.12
Page(s) 104-108
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Bauhinia rufescens, Gairdia lameblia, Metronidazol

References
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[7] Newman, R. D. Moore, S. R. Lima, A. A. Nataro, J. P. Guerrant, R. L. Sears, C. L. (2001). A longitudinal study of Giardia lamblia infection in north-east Brazilian children. Trop. Med. Int. Health 6:624–634.
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Cite This Article
  • APA Style

    Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. (2017). Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. American Journal of Bioscience and Bioengineering, 5(5), 104-108. https://doi.org/10.11648/j.bio.20170505.12

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    ACS Style

    Mohamed Ismail Garbi; Elbadri Elamin Osman; Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am. J. BioSci. Bioeng. 2017, 5(5), 104-108. doi: 10.11648/j.bio.20170505.12

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    AMA Style

    Mohamed Ismail Garbi, Elbadri Elamin Osman, Ahmed Saeed Kabbashi. Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia. Am J BioSci Bioeng. 2017;5(5):104-108. doi: 10.11648/j.bio.20170505.12

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  • @article{10.11648/j.bio.20170505.12,
      author = {Mohamed Ismail Garbi and Elbadri Elamin Osman and Ahmed Saeed Kabbashi},
      title = {Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia},
      journal = {American Journal of Bioscience and Bioengineering},
      volume = {5},
      number = {5},
      pages = {104-108},
      doi = {10.11648/j.bio.20170505.12},
      url = {https://doi.org/10.11648/j.bio.20170505.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.bio.20170505.12},
      abstract = {Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Comparison of the Antiparasitic Activity of Bauhinia rufescens Leaves Extracts and Metronidazole Against Gairdia lamblia
    AU  - Mohamed Ismail Garbi
    AU  - Elbadri Elamin Osman
    AU  - Ahmed Saeed Kabbashi
    Y1  - 2017/11/22
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    N1  - https://doi.org/10.11648/j.bio.20170505.12
    DO  - 10.11648/j.bio.20170505.12
    T2  - American Journal of Bioscience and Bioengineering
    JF  - American Journal of Bioscience and Bioengineering
    JO  - American Journal of Bioscience and Bioengineering
    SP  - 104
    EP  - 108
    PB  - Science Publishing Group
    SN  - 2328-5893
    UR  - https://doi.org/10.11648/j.bio.20170505.12
    AB  - Giardia is a flagellate protozoan with worldwide distribution that causes significant gastrointestinal diseases in a wide variety of vertebrates including cats and human. Gairdia lamblia is one of the intestinal protozoa that cause public health problems in most developing countries as well as some developed countries. This study was carried out to evaluate Antigiardial activity of Bauhinia rufsescens (Leaves) petroleum ether and methanolic extracts in vitro test were perform using four concentrations: (1000, 500, 250 and 125 ppm). The highest activity against G. lameblia with respect to time was obtained from petroleum ether extract which exhibited 77.12% mortality within 72 h in 1000 ppm concentration, followed by the same extract which exhibited 76.04% mortality within 72 h with concentration of 500 ppm. On the other hand, the lowest antigiardial activity was recorded by B. rufescens petroleum ether extract 82.8% mortality with 125 ppm concentration within 24 hours, with whereas Metronidazol, a pure compound (positive control) showed 83.42% mortality within 72 hours. This result shows that the most potent antigiardial activity was demonstrated in B. rufescens petroleum ether extract at all concentrations (i.e. 74% mortality within 72 hours) and that B. rufescens species, as claimed also by tradition, is a promising species in treating G. lamblia.
    VL  - 5
    IS  - 5
    ER  - 

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Author Information
  • Department of Microbiology and Parasitology, Faculty of Medical Laboratory Sciences, Ibn Sina University, Khartoum, Sudan

  • Department of Microbiology, Faculty of Pure and Applied Sciences, International University of Africa, Khartoum, Sudan

  • Department of Microbiology, Faculty of Medical Laboratory Sciences, International University of Africa, Khartoum, Sudan

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