American Journal of Laboratory Medicine

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The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia

Received: Apr. 22, 2023    Accepted: Jun. 12, 2023    Published: Jul. 06, 2023
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Abstract

Diabetes has been a rising health burden universally. It is defined as a group of metabolic disorders that result in high serum glucose levels which can be caused by a deficiency of insulin or a defect in its action. Cardiovascular complication is the main cause of death in the diabetic population. Of which, dyslipidemia is the principal factor associated with cardiovascular disease in the T2DM population. However, early detection and treatment of dyslipidemia in T2DM patients can prevent the progression of dyslipidemia & minimize the risk of CVS disease-related morbidity and death significantly. And for there is a paucity of data on the magnitude of dyslipidemia & associated factors among T2DM patients in Ethiopia, we conducted an institution-based cross-sectional analytic study at SPHMMC endocrinology clinic from January 1 to February 28 2022 G.C. The data for the study is collected by a structured checklist and it is entered, cleaned & analyzed using SPSS version 26.0. Descriptive analyses like frequency distribution, proportion and dispersion were calculated. And the finding is presented using frequency tables, graphs, and charts. Both univariate and multivariate analyses were done. The OR with 95% CI was used to show the strength of the association and a P value of <0.05 was considered statistically significant. In the study, a total of 270 type 2 DM patients were enrolled and all of them were included in the analysis. The magnitude of dyslipidemia revealed from the study was 93.7%. Out of those who have dyslipidemia, 13.7%, 64.8%, 70% and 34.8% of the participants had high TC, low HDL, high LDL and high triglyceride levels, respectively. In multiple regression analysis, only sex showed statistical significance at p-value < 0.05. The odds of having dyslipidemia was 7-fold increased (AOR=95% CI (1.251-43.421)) in type 2 DM patients. As a conclusion, the magnitude of dyslipidemia was found to be 93.7% of the total participants which is higher than most of the studies which were done inside and outside Ethiopia. And being female was associated with a risk of developing dyslipidemia. Thus, health professionals should screen and monitor dyslipidemia in all type 2 DM patients especially females.

DOI 10.11648/j.ajlm.20230802.11
Published in American Journal of Laboratory Medicine ( Volume 8, Issue 2, March 2023 )
Page(s) 13-20
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

T2DM, Dyslipidemia, FBG, HbA1C, Endocrinology Clinic, SPHMMC

References
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[8] Chaudhury D, Aggarwal A. Diabetic dyslipidemia: Current concepts in pathophysiology and management. Vol. 12, Journal of Clinical and Diagnostic Research. Journal of Clinical and Diagnostic Research; 2018. p. OE06–9.
[9] Díaz Vera AS, Abellán Alemán J, Segura Fragoso A, Martínez de Esteban JP, Lameiro Couso FJ, Golac Rabanal M del S, et al. The prevalence and risk factors associated with dyslipidemia in type 2 diabetic patients in the autonomous Region of Cantabria. Endocrinol Diabetes y Nutr (English ed). 2020 Feb; 67 (2): 102–12.
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  • APA Style

    Tsion Habtamu Ababiya, Robel Habtamu Ababiya, Yohannes Gizachew Achamyeleh, Peniel Yigezu Sedi, Rediet Ajebu Nurfeta, et al. (2023). The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia. American Journal of Laboratory Medicine, 8(2), 13-20. https://doi.org/10.11648/j.ajlm.20230802.11

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    ACS Style

    Tsion Habtamu Ababiya; Robel Habtamu Ababiya; Yohannes Gizachew Achamyeleh; Peniel Yigezu Sedi; Rediet Ajebu Nurfeta, et al. The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia. Am. J. Lab. Med. 2023, 8(2), 13-20. doi: 10.11648/j.ajlm.20230802.11

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    AMA Style

    Tsion Habtamu Ababiya, Robel Habtamu Ababiya, Yohannes Gizachew Achamyeleh, Peniel Yigezu Sedi, Rediet Ajebu Nurfeta, et al. The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia. Am J Lab Med. 2023;8(2):13-20. doi: 10.11648/j.ajlm.20230802.11

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  • @article{10.11648/j.ajlm.20230802.11,
      author = {Tsion Habtamu Ababiya and Robel Habtamu Ababiya and Yohannes Gizachew Achamyeleh and Peniel Yigezu Sedi and Rediet Ajebu Nurfeta and Sintayehu Dagnaw Dinberu and Esrom Hagos Gebrehiwot and Berhanu Lijalem Yigezu and Amanuel Paulos Genebo and Selamawit Abebe Ayele},
      title = {The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia},
      journal = {American Journal of Laboratory Medicine},
      volume = {8},
      number = {2},
      pages = {13-20},
      doi = {10.11648/j.ajlm.20230802.11},
      url = {https://doi.org/10.11648/j.ajlm.20230802.11},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajlm.20230802.11},
      abstract = {Diabetes has been a rising health burden universally. It is defined as a group of metabolic disorders that result in high serum glucose levels which can be caused by a deficiency of insulin or a defect in its action. Cardiovascular complication is the main cause of death in the diabetic population. Of which, dyslipidemia is the principal factor associated with cardiovascular disease in the T2DM population. However, early detection and treatment of dyslipidemia in T2DM patients can prevent the progression of dyslipidemia & minimize the risk of CVS disease-related morbidity and death significantly. And for there is a paucity of data on the magnitude of dyslipidemia & associated factors among T2DM patients in Ethiopia, we conducted an institution-based cross-sectional analytic study at SPHMMC endocrinology clinic from January 1 to February 28 2022 G.C. The data for the study is collected by a structured checklist and it is entered, cleaned & analyzed using SPSS version 26.0. Descriptive analyses like frequency distribution, proportion and dispersion were calculated. And the finding is presented using frequency tables, graphs, and charts. Both univariate and multivariate analyses were done. The OR with 95% CI was used to show the strength of the association and a P value of <0.05 was considered statistically significant. In the study, a total of 270 type 2 DM patients were enrolled and all of them were included in the analysis. The magnitude of dyslipidemia revealed from the study was 93.7%. Out of those who have dyslipidemia, 13.7%, 64.8%, 70% and 34.8% of the participants had high TC, low HDL, high LDL and high triglyceride levels, respectively. In multiple regression analysis, only sex showed statistical significance at p-value < 0.05. The odds of having dyslipidemia was 7-fold increased (AOR=95% CI (1.251-43.421)) in type 2 DM patients. As a conclusion, the magnitude of dyslipidemia was found to be 93.7% of the total participants which is higher than most of the studies which were done inside and outside Ethiopia. And being female was associated with a risk of developing dyslipidemia. Thus, health professionals should screen and monitor dyslipidemia in all type 2 DM patients especially females.},
     year = {2023}
    }
    

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    T1  - The Magnitude of Dyslipidemia & Associated Factors Among Patients with Type 2 DM Who Are in Follow-up in Adult Endocrine Clinic at SPHMMC, Addis Ababa, Ethiopia
    AU  - Tsion Habtamu Ababiya
    AU  - Robel Habtamu Ababiya
    AU  - Yohannes Gizachew Achamyeleh
    AU  - Peniel Yigezu Sedi
    AU  - Rediet Ajebu Nurfeta
    AU  - Sintayehu Dagnaw Dinberu
    AU  - Esrom Hagos Gebrehiwot
    AU  - Berhanu Lijalem Yigezu
    AU  - Amanuel Paulos Genebo
    AU  - Selamawit Abebe Ayele
    Y1  - 2023/07/06
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ajlm.20230802.11
    DO  - 10.11648/j.ajlm.20230802.11
    T2  - American Journal of Laboratory Medicine
    JF  - American Journal of Laboratory Medicine
    JO  - American Journal of Laboratory Medicine
    SP  - 13
    EP  - 20
    PB  - Science Publishing Group
    SN  - 2575-386X
    UR  - https://doi.org/10.11648/j.ajlm.20230802.11
    AB  - Diabetes has been a rising health burden universally. It is defined as a group of metabolic disorders that result in high serum glucose levels which can be caused by a deficiency of insulin or a defect in its action. Cardiovascular complication is the main cause of death in the diabetic population. Of which, dyslipidemia is the principal factor associated with cardiovascular disease in the T2DM population. However, early detection and treatment of dyslipidemia in T2DM patients can prevent the progression of dyslipidemia & minimize the risk of CVS disease-related morbidity and death significantly. And for there is a paucity of data on the magnitude of dyslipidemia & associated factors among T2DM patients in Ethiopia, we conducted an institution-based cross-sectional analytic study at SPHMMC endocrinology clinic from January 1 to February 28 2022 G.C. The data for the study is collected by a structured checklist and it is entered, cleaned & analyzed using SPSS version 26.0. Descriptive analyses like frequency distribution, proportion and dispersion were calculated. And the finding is presented using frequency tables, graphs, and charts. Both univariate and multivariate analyses were done. The OR with 95% CI was used to show the strength of the association and a P value of <0.05 was considered statistically significant. In the study, a total of 270 type 2 DM patients were enrolled and all of them were included in the analysis. The magnitude of dyslipidemia revealed from the study was 93.7%. Out of those who have dyslipidemia, 13.7%, 64.8%, 70% and 34.8% of the participants had high TC, low HDL, high LDL and high triglyceride levels, respectively. In multiple regression analysis, only sex showed statistical significance at p-value < 0.05. The odds of having dyslipidemia was 7-fold increased (AOR=95% CI (1.251-43.421)) in type 2 DM patients. As a conclusion, the magnitude of dyslipidemia was found to be 93.7% of the total participants which is higher than most of the studies which were done inside and outside Ethiopia. And being female was associated with a risk of developing dyslipidemia. Thus, health professionals should screen and monitor dyslipidemia in all type 2 DM patients especially females.
    VL  - 8
    IS  - 2
    ER  - 

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Author Information
  • Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

  • Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

  • Department of Internal Medicine, Worabe Comprehensive Specialized Hospital, Worabe, Ethiopia

  • Department of Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

  • Department of Internal Medicine, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia

  • Department of Internal Medicine, Bahir Dar University, Bahir Dar, Ethiopia

  • Department of Internal Medicine, Wollo University, Dessie, Ethiopia

  • Department of Radiology, Hawassa University College of Medicine and Health Science, Hawassa, Ethiopia

  • Department of Internal Medicine, Wolaita Sodo University Comprehensive Specialized Hospital, Wolaita Sodo, Ethiopia

  • Department of Pathology, Hawassa University College of Medicine and Health Science, Hawassa, Ethiopia

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