Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO<sub>3</sub>H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst

Ali Gharib; Nader Noroozi Pesyan; Leila Vojdani Fard; Mina Roshani

doi:doi:10.11648/j.ajhc.20150101.11

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Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO₃H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst

Ali Gharib, Nader Noroozi Pesyan, Leila Vojdani Fard, Mina Roshani

Published in American Journal of Heterocyclic Chemistry (Volume 1, Issue 1)

Received: 10 April 2015 Accepted: 22 April 2015 Published: 28 April 2015

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Abstract

In this method, at first the synthesis of 2,3-dihydro-1H-carbazol-4(9H)-one product by the condensation of (Z)-3-(2-phenylhydrazono)cyclohexanone in the presence of (SBA-Pr-SO3H) as nanoporous solid acid catalyst, acid acetic glacial and ethanol as solvent under reflux conditions is reported. (SBA-Pr-SO3H) nanoporous solid acid catalyst was used as an effective catalyst for the synthesis of Carvedilol from the reaction of 4-oxiranylmethyoxy-9H-carbazole and 2-(2-methoxyphenoxy)ethanamine in the presence of monoglyme solvent. This synthesis afforded under ring opening of 4-oxiranylmethyoxy-9H-carbazole with 2-(2-methoxyphenoxy)ethanamine by above nano-catalyst. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.

Published in	American Journal of Heterocyclic Chemistry (Volume 1, Issue 1)
DOI	10.11648/j.ajhc.20150101.11
Page(s)	1-5
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Carvedilol, Nano-Catalyst, Carbazole, Heterogeneous, (SBA-Pr-SO3H), Synthesis

References

[1]	J. N. Joyce, N. Lexow, S. J. Kim, R. Artymyshyn, S. Senzon, D. Lawrence, M. F. Cassanova, J. R. Kleinman, E. D. Bird, A. Winokur, Synapse. 1992, 10, 228.
[2]	L. M. Kukin; J. Kalman; H. R. Charney; K. D. Levy; C. Buchholz-Varely; N. O. Ocampo;C. Eng, Circulation. 1999, 99, 2645.
[3]	M. Packer, B. M. Fowler, B. E. Roecker, J. S. A. Coats, A. H. Katus, H. Krum, P. Mohacsi, L. J. Rouleau, M. Tendera, C. Staiger, L. T. Holcslaw, I. Amann-Zalah, L. D. DeMets, Circulation. 2002, 106, 2194.
[4]	S. Beck, J. C. Vartuli, W. J. Roth, C. T. Kresge, M. E. Leonowicz, K. D. Schmitt, C.T-W Chu, D. H. Olson, E. W. Sheppard, S. B. McCullen, J. B. Higgins, J. L. Schlenker, J. Am. Chem. Soc. 1992, 114, 10834.
[5]	P. Reinert, B. Garcia, C. Morin, A. Badiei, P. Perriat, O. Tillement, L. Bonneviot, Stud. Surf. Sci. Catal. 2003, 146, 133.
[6]	D. Zhao, Q. Huo, J. Feng, B. F. Chmelka, G. D. Stucky, J. Am. Chem. Soc. 1998, 120, 6024.
[7]	D. Trong On, D. Desplantier-Giscard, C. Danumah, S. Kaliaguine, Appl. Catal. A: Gen. 2001, 222, 299.
[8]	M. R. Ganjali, A. Daftari, L. Hajiagha Babaei, K. Saberyan, G. Mohammadi Ziarani, A. Moghimi, Water, Air, Soil Pollut. 2006, 173, 71.
[9]	A. Badiei, P. Norouzi, F. Tousi, Eur. J. Sci. Res. 2005, 12, 39.
[10]	M. H. Lim, C. F. Blanford, A. Stein, Chem. Mater. 1998, 10, 467.
[11]	M. Onaka, N. Hashimoto, Y. Kitabata, R. Yamasaki, Appl. Catal. A: General. 2003, 241, 307.
[12]	R. I. Kureshy, I. Ahmad, K. Pathak, N. H. Khan, S. H. R. Abdi, R. V. Jasra, Catal. Commun. 2009, 10, 572.
[13]	B. Karimi, D. Zareyee, Org. Lett. 2008, 10, 3989.
[14]	A. Gharib, N. N. Pesyan, B. R. H. Khorasani, M. Roshani, J. (HANS) W. Scheeren, Bulgarian Chemical Communications. 2013, 45, 371.
[15]	A. Liu, G. Lu, Acta Pharmaceutica Sinica, 1994, 29, 793.
[16]	G. M. Ziarani, A. Badiei, Y. Khaniania, Iranian Journal of Chemistry and Chemical Engineering, 2010, 29, 1.

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Ali Gharib, Nader Noroozi Pesyan, Leila Vojdani Fard, Mina Roshani. (2015). Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. American Journal of Heterocyclic Chemistry, 1(1), 1-5. https://doi.org/10.11648/j.ajhc.20150101.11

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ACS Style

Ali Gharib; Nader Noroozi Pesyan; Leila Vojdani Fard; Mina Roshani. Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. Am. J. Heterocycl. Chem. 2015, 1(1), 1-5. doi: 10.11648/j.ajhc.20150101.11

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AMA Style

Ali Gharib, Nader Noroozi Pesyan, Leila Vojdani Fard, Mina Roshani. Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. Am J Heterocycl Chem. 2015;1(1):1-5. doi: 10.11648/j.ajhc.20150101.11

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@article{10.11648/j.ajhc.20150101.11,
  author = {Ali Gharib and Nader Noroozi Pesyan and Leila Vojdani Fard and Mina Roshani},
  title = {Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst},
  journal = {American Journal of Heterocyclic Chemistry},
  volume = {1},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ajhc.20150101.11},
  url = {https://doi.org/10.11648/j.ajhc.20150101.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhc.20150101.11},
  abstract = {In this method, at first the synthesis of 2,3-dihydro-1H-carbazol-4(9H)-one product by the condensation of (Z)-3-(2-phenylhydrazono)cyclohexanone in the presence of (SBA-Pr-SO3H) as nanoporous solid acid catalyst, acid acetic glacial and ethanol as solvent under reflux conditions is reported. (SBA-Pr-SO3H) nanoporous solid acid catalyst was used as an effective catalyst for the synthesis of Carvedilol from the reaction of 4-oxiranylmethyoxy-9H-carbazole and 2-(2-methoxyphenoxy)ethanamine in the presence of monoglyme solvent. This synthesis afforded under ring opening of 4-oxiranylmethyoxy-9H-carbazole with 2-(2-methoxyphenoxy)ethanamine by above nano-catalyst. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.},
 year = {2015}
}

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TY  - JOUR
T1  - Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst
AU  - Ali Gharib
AU  - Nader Noroozi Pesyan
AU  - Leila Vojdani Fard
AU  - Mina Roshani
Y1  - 2015/04/28
PY  - 2015
N1  - https://doi.org/10.11648/j.ajhc.20150101.11
DO  - 10.11648/j.ajhc.20150101.11
T2  - American Journal of Heterocyclic Chemistry
JF  - American Journal of Heterocyclic Chemistry
JO  - American Journal of Heterocyclic Chemistry
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2575-5722
UR  - https://doi.org/10.11648/j.ajhc.20150101.11
AB  - In this method, at first the synthesis of 2,3-dihydro-1H-carbazol-4(9H)-one product by the condensation of (Z)-3-(2-phenylhydrazono)cyclohexanone in the presence of (SBA-Pr-SO3H) as nanoporous solid acid catalyst, acid acetic glacial and ethanol as solvent under reflux conditions is reported. (SBA-Pr-SO3H) nanoporous solid acid catalyst was used as an effective catalyst for the synthesis of Carvedilol from the reaction of 4-oxiranylmethyoxy-9H-carbazole and 2-(2-methoxyphenoxy)ethanamine in the presence of monoglyme solvent. This synthesis afforded under ring opening of 4-oxiranylmethyoxy-9H-carbazole with 2-(2-methoxyphenoxy)ethanamine by above nano-catalyst. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.
VL  - 1
IS  - 1
ER  -

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Author Information

Ali Gharib

Department of Chemistry, Islamic Azad University, Mashhad, Iran
Nader Noroozi Pesyan

Department of Chemistry, Faculty of Science, Urmia University, Urmia, Iran
Leila Vojdani Fard

Education Ministry, Education Organization of Razavi Khorasan, Mashhad, Iran
Mina Roshani

Department of Chemistry, Islamic Azad University, Mashhad, Iran

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APA Style

Ali Gharib, Nader Noroozi Pesyan, Leila Vojdani Fard, Mina Roshani. (2015). Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. American Journal of Heterocyclic Chemistry, 1(1), 1-5. https://doi.org/10.11648/j.ajhc.20150101.11

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ACS Style

Ali Gharib; Nader Noroozi Pesyan; Leila Vojdani Fard; Mina Roshani. Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. Am. J. Heterocycl. Chem. 2015, 1(1), 1-5. doi: 10.11648/j.ajhc.20150101.11

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AMA Style

Ali Gharib, Nader Noroozi Pesyan, Leila Vojdani Fard, Mina Roshani. Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst. Am J Heterocycl Chem. 2015;1(1):1-5. doi: 10.11648/j.ajhc.20150101.11

Copy | Download

@article{10.11648/j.ajhc.20150101.11,
  author = {Ali Gharib and Nader Noroozi Pesyan and Leila Vojdani Fard and Mina Roshani},
  title = {Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst},
  journal = {American Journal of Heterocyclic Chemistry},
  volume = {1},
  number = {1},
  pages = {1-5},
  doi = {10.11648/j.ajhc.20150101.11},
  url = {https://doi.org/10.11648/j.ajhc.20150101.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajhc.20150101.11},
  abstract = {In this method, at first the synthesis of 2,3-dihydro-1H-carbazol-4(9H)-one product by the condensation of (Z)-3-(2-phenylhydrazono)cyclohexanone in the presence of (SBA-Pr-SO3H) as nanoporous solid acid catalyst, acid acetic glacial and ethanol as solvent under reflux conditions is reported. (SBA-Pr-SO3H) nanoporous solid acid catalyst was used as an effective catalyst for the synthesis of Carvedilol from the reaction of 4-oxiranylmethyoxy-9H-carbazole and 2-(2-methoxyphenoxy)ethanamine in the presence of monoglyme solvent. This synthesis afforded under ring opening of 4-oxiranylmethyoxy-9H-carbazole with 2-(2-methoxyphenoxy)ethanamine by above nano-catalyst. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Synthesis of β-Receptor Blocker and Antihypertensive Drug Using (SBA-Pr-SO3H) as an Eco-Friendly, Inexpensive and Efficient Nano-Catalyst
AU  - Ali Gharib
AU  - Nader Noroozi Pesyan
AU  - Leila Vojdani Fard
AU  - Mina Roshani
Y1  - 2015/04/28
PY  - 2015
N1  - https://doi.org/10.11648/j.ajhc.20150101.11
DO  - 10.11648/j.ajhc.20150101.11
T2  - American Journal of Heterocyclic Chemistry
JF  - American Journal of Heterocyclic Chemistry
JO  - American Journal of Heterocyclic Chemistry
SP  - 1
EP  - 5
PB  - Science Publishing Group
SN  - 2575-5722
UR  - https://doi.org/10.11648/j.ajhc.20150101.11
AB  - In this method, at first the synthesis of 2,3-dihydro-1H-carbazol-4(9H)-one product by the condensation of (Z)-3-(2-phenylhydrazono)cyclohexanone in the presence of (SBA-Pr-SO3H) as nanoporous solid acid catalyst, acid acetic glacial and ethanol as solvent under reflux conditions is reported. (SBA-Pr-SO3H) nanoporous solid acid catalyst was used as an effective catalyst for the synthesis of Carvedilol from the reaction of 4-oxiranylmethyoxy-9H-carbazole and 2-(2-methoxyphenoxy)ethanamine in the presence of monoglyme solvent. This synthesis afforded under ring opening of 4-oxiranylmethyoxy-9H-carbazole with 2-(2-methoxyphenoxy)ethanamine by above nano-catalyst. Heterogeneous reaction conditions, easy procedure, short reaction time, and high yields are some important advantages of this method.
VL  - 1
IS  - 1
ER  -

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