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Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire

Received: 11 October 2021     Accepted: 13 November 2021     Published: 19 November 2021
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Abstract

Acute Respiratory Infections (ARI) are, after malaria, the second most common cause of consultation of children in health facilities in Côte d'Ivoire. Viral etiology points to Respiratory Syncytial Virus (RSV) as the primary cause of these acute respiratory infections. In order to better assist health workers in diagnosing the virus, a study on the epidemiology, seasonality and clinical signs associated with RSV acute respiratory infections was conducted over four consecutive years. During these years, nasopharyngeal samples were collected from 5648 children aged 0-5 years, in different geographical areas of the country, following a survey form for analysis by real-time PCR, to detect the virus and describe its epidemiological characteristics. Our results revealed 564 (9.98%) RSV positive children. A number of 181 (32.09%) were positive in inpatients, and 383 (67.91%) in outpatients. The 0-12 month age group was the most affected with 51.95% of positive cases. Cumulative monthly RSV activity for the 4 years of the study was relatively lower during the months of January to March and higher during the months of May to September. This distribution of RSV was superimposed on rainfall during these study years. Our work has also linked RSV positivity to the presence of clinical signs, including fever, cough, diarrhoea and vomiting. These results give scientific tools to health personnel to better orient their diagnosis and also a better rational use in the prescription of medication, notably the stopping of unjustified antibiotic therapy.

Published in American Journal of BioScience (Volume 9, Issue 6)
DOI 10.11648/j.ajbio.20210906.13
Page(s) 185-191
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Respiratory Syncytial Virus, Surveillance, Children, Seasonality

References
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  • APA Style

    Venance Kouakou, Hervé Kadjo, N'nan Alla Oulo, Fidèle Diobo N'guessan, Adèle N'Douba. (2021). Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire. American Journal of BioScience, 9(6), 185-191. https://doi.org/10.11648/j.ajbio.20210906.13

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    ACS Style

    Venance Kouakou; Hervé Kadjo; N'nan Alla Oulo; Fidèle Diobo N'guessan; Adèle N'Douba. Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire. Am. J. BioScience 2021, 9(6), 185-191. doi: 10.11648/j.ajbio.20210906.13

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    AMA Style

    Venance Kouakou, Hervé Kadjo, N'nan Alla Oulo, Fidèle Diobo N'guessan, Adèle N'Douba. Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire. Am J BioScience. 2021;9(6):185-191. doi: 10.11648/j.ajbio.20210906.13

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  • @article{10.11648/j.ajbio.20210906.13,
      author = {Venance Kouakou and Hervé Kadjo and N'nan Alla Oulo and Fidèle Diobo N'guessan and Adèle N'Douba},
      title = {Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire},
      journal = {American Journal of BioScience},
      volume = {9},
      number = {6},
      pages = {185-191},
      doi = {10.11648/j.ajbio.20210906.13},
      url = {https://doi.org/10.11648/j.ajbio.20210906.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajbio.20210906.13},
      abstract = {Acute Respiratory Infections (ARI) are, after malaria, the second most common cause of consultation of children in health facilities in Côte d'Ivoire. Viral etiology points to Respiratory Syncytial Virus (RSV) as the primary cause of these acute respiratory infections. In order to better assist health workers in diagnosing the virus, a study on the epidemiology, seasonality and clinical signs associated with RSV acute respiratory infections was conducted over four consecutive years. During these years, nasopharyngeal samples were collected from 5648 children aged 0-5 years, in different geographical areas of the country, following a survey form for analysis by real-time PCR, to detect the virus and describe its epidemiological characteristics. Our results revealed 564 (9.98%) RSV positive children. A number of 181 (32.09%) were positive in inpatients, and 383 (67.91%) in outpatients. The 0-12 month age group was the most affected with 51.95% of positive cases. Cumulative monthly RSV activity for the 4 years of the study was relatively lower during the months of January to March and higher during the months of May to September. This distribution of RSV was superimposed on rainfall during these study years. Our work has also linked RSV positivity to the presence of clinical signs, including fever, cough, diarrhoea and vomiting. These results give scientific tools to health personnel to better orient their diagnosis and also a better rational use in the prescription of medication, notably the stopping of unjustified antibiotic therapy.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Surveillance of Respiratory Syncytial Virus in Children Aged 0-5 years in Côte d'Ivoire
    AU  - Venance Kouakou
    AU  - Hervé Kadjo
    AU  - N'nan Alla Oulo
    AU  - Fidèle Diobo N'guessan
    AU  - Adèle N'Douba
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    T2  - American Journal of BioScience
    JF  - American Journal of BioScience
    JO  - American Journal of BioScience
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    EP  - 191
    PB  - Science Publishing Group
    SN  - 2330-0167
    UR  - https://doi.org/10.11648/j.ajbio.20210906.13
    AB  - Acute Respiratory Infections (ARI) are, after malaria, the second most common cause of consultation of children in health facilities in Côte d'Ivoire. Viral etiology points to Respiratory Syncytial Virus (RSV) as the primary cause of these acute respiratory infections. In order to better assist health workers in diagnosing the virus, a study on the epidemiology, seasonality and clinical signs associated with RSV acute respiratory infections was conducted over four consecutive years. During these years, nasopharyngeal samples were collected from 5648 children aged 0-5 years, in different geographical areas of the country, following a survey form for analysis by real-time PCR, to detect the virus and describe its epidemiological characteristics. Our results revealed 564 (9.98%) RSV positive children. A number of 181 (32.09%) were positive in inpatients, and 383 (67.91%) in outpatients. The 0-12 month age group was the most affected with 51.95% of positive cases. Cumulative monthly RSV activity for the 4 years of the study was relatively lower during the months of January to March and higher during the months of May to September. This distribution of RSV was superimposed on rainfall during these study years. Our work has also linked RSV positivity to the presence of clinical signs, including fever, cough, diarrhoea and vomiting. These results give scientific tools to health personnel to better orient their diagnosis and also a better rational use in the prescription of medication, notably the stopping of unjustified antibiotic therapy.
    VL  - 9
    IS  - 6
    ER  - 

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Author Information
  • Respiratory Virus Unit, Institute Pasteur of C?te d'Ivoire, Abidjan, C?te d’Ivoire

  • Respiratory Virus Unit, Institute Pasteur of C?te d'Ivoire, Abidjan, C?te d’Ivoire

  • Genetics Laboratory, Felix Houphou?t Boigny University, Abidjan, C?te d'Ivoire

  • Respiratory Virus Unit, Institute Pasteur of C?te d'Ivoire, Abidjan, C?te d’Ivoire

  • Microbiology Teaching Unit, Felix Houphou?t Boigny University, Abidjan C?te d'Ivoire

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