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Case Report |

Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger)

Kaposi sarcoma (KS), first described in 1872 by the dermatologist Moricz Cohen Kaposi, is the most common neoplasm of people living with HIV today. Kaposi Sarcoma remains the most common cancer in people living with HIV in sub-Saharan Africa, where it causes significant morbidity and mortality. We report the case of two patients from Niger, aged 43 and 65 years old, who consulted unit of HIV care the Niamey Regional Hospital for an exploration of skin lesions in a context of altered general condition including significant weight loss. The clinical diagnosis of Kaposi's disease on a background of HIV immunodeficiency was retained. The clinical lesions were infiltrating cuteneous bluish nodular skin lesions with macules located on the legs, forearm and abdomen. The treatment consisted in putting the patients on high antiretroviral treatment followed by courses of chemotherapy. The combination of high antiretroviral therapy was started with TDF-3TC-EFV one tablet daily at bedtime. These study show the clinical polymorphism, the diagnostic delay and the treatment including polychemotherapy and antiretroviral drugs. Early diagnosis and detection of lesions could improve management and the prognosis of this disease.

Cutaneous Kaposi's Disease, HIV/AIDS Disease, ART CHR/Niamey Niger

APA Style

Sani, K., Amadou Mahaman Laouali, H., Almoustapha Amadou, D., Abdoul Azize, G., Ibrahim Alkassoum, S., et al. (2023). Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). International Journal of Medical Case Reports, 2(4), 24-27. https://doi.org/10.11648/j.ijmcr.20230204.11

ACS Style

Sani, K.; Amadou Mahaman Laouali, H.; Almoustapha Amadou, D.; Abdoul Azize, G.; Ibrahim Alkassoum, S., et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int. J. Med. Case Rep. 2023, 2(4), 24-27. doi: 10.11648/j.ijmcr.20230204.11

AMA Style

Sani K, Amadou Mahaman Laouali H, Almoustapha Amadou D, Abdoul Azize G, Ibrahim Alkassoum S, et al. Cutaneous Kaposi Sarcoma Indicative of HIV/AIDS Infection: Two Cases Report and Review of the Literature at Regional Hospital Centre of Niamey (Niger). Int J Med Case Rep. 2023;2(4):24-27. doi: 10.11648/j.ijmcr.20230204.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Hanae Bouzidi, Salim Gallouj, Sanae Krich, et Fatima Zahra Mernissi Classic Kaposi disease with adrenal involvement: a new case The Pan Africa Medical Journal- ISSN1937-8688. African Field Epidemiology Network.
2. B. Saka, A. Mouhari-Toure, I. M. Wateba, S. Akakpo, K. Kombaté, A. Balaka, A. Sogan, K. O. Afolabi, P. Pitché, K Tchangaï-Walla, Maladie de Kaposi associée au VIH: 103 observations en dermatologie à Lomé (Togo). Médecine et santé tropicale, Janvier-Février-Mars 2013 Volume 23, numéro 1.
3. Ndiaye Maodo, Diop Assane, Berthe Siritio, Diallo Moussa, Mjahed Sara Diatta Boubacar Ahy, Diadie Saer, Seck Ndeye Bougoul, Diallo Salimatou, Ndiaye Mame Tene, Niang Suzanne Oumou, Ly Fatimata, Dieng Mame Thierno, Kane Assane, MALADIE DE KAPOSI ENDEMIQUE A DAKAR: ETUDE DE 29 CAS.
4. C. Francès, C. Lebbé, La maladie de Kaposi: La Lettre du Cancérologue - septembre 2010 • Vol. XIX - n° 7.
5. Mouna Lamchahab, Bouchra Oukkache, Sofia Marouan, Asmae Quessar, Said Benchekroun, Maladie de kaposi compliquant une aplasie médullaire Pan Afr Med J. 2014; 18: 169.
6. Martellotta F, Berretta M, Vaccher E, Schioppa O, Zanet E, Tirelli U. AIDS-related Kaposi's sarcoma: state of the art and therapeutic strategies. Curr HIV Res. 2009; 7 (6): 634–8.
7. P. Philibert, L. Chiche, F. Retornez, M. Delord, S. Rebaudet, C. Stavris, S. Cailleres, J. Allemand, H. Kihri, P. Halfon Sarcome de Kaposi associé au VIH: à propos d’un cas illustrant le caractère protecteur des inhibiteurs de protéase du VIH. La Revue de Médecine Interne Volume 38, Supplement 1, June 2017, Pages A220-A221.
8. PILLY E. Collège des universitaires de maladies infectieuses et tropicales. In: Pilly E, editor. Infection à VIH et sida. Vivactis plus Ed; 2006. p. 494.
9. Kristina Narančić-Skorić, Hrvoje Brajčić, Mirjana Sabljar-Matovinović, Tajana Filipec-Kanižaj, Maruška Marušić-Vrsalović, Mladen Knotek, Ingrid Prkačin, Dinko Škegro, Slavko Gašparov. Classic Kaposi’s Sarcoma: A Case Report. Acta Dermatovenerol Croat 2005; 13 (1) 22-27.
10. Jiasen Wang, BA, Holly Reid, MD, Natasha Klimas, MD, and Misha Koshelev, Houston, Texas. An unusual series of patients with Kaposi sarcoma. JAAD Case Reports 2019; 5: 646-9.
11. Shehzeen Fatima Memon_, Anosh Aslam Khan_, Yasir Ahmad Khan_ and Hafsa Mahmood. Classic Kaposi’s Sarcoma in an exclusively cutaneous exhibition. International Journal of Medical Reviews and Case Reports (2019) 3 (9): 620-623.
12. David Sandoval Sanchez, Estanislao Antonio Calixto, Roberto Peralta Juárez, Marcos, García Aranda, Rolando Castellanos Villalobos, Jessica Ariatna Carreto Navarrete. Extensive Kaposi's sarcoma in a Patient with Acquired Immunodeficiency Syndrome: Case International. Journal of Medical Science and Clinical Research Studies, Report Volume 03 Issue 01 Janaury 2023 Page No: 68-70. DOI: https://doi.org/10.47191/ijmscrs/v3-i1-14
13. Ujjwal Joshi, Denny E Ceena, Ravikiran Ongole, KN Sumanth, Karen Boaz, K Jeena Priya, N Srikant. AIDS Related Kaposi’s Sarcoma presenting with Palatal and Eyelid Nodule. JAPI july 2012 VOL. 60.
14. Mudau A, Makhanya NZ, Suleman FE. Disseminated Kaposi sarcoma presenting in unusual locations: A case report. S Afr J Rad. 2017; 21 (2), a1260. https:// doi.org/10.4102/sajr. v21i2.1260
15. Oana Radu; Liron Pantanowitz. Kaposi Sarcoma. Arch Pathol Lab Med—Vol 137, February 2013. P 289-294.
16. Darung I, Shah N, Ghosh A, Kamgo L, Kavishwar V. Classic Kaposi sarcoma in Eastern India. Indian J Dermatol Venereol Leprol doi: 10.25259/IJDVL_942_2021.
17. Akca Hanife Merve, A Case of Neglected Classıc Kaposı’s Sarcoma. J Clin Med Img Case Rep. 2022; 2 (2): 1106.
18. Kiran Alam, Veena Maheshwari, Manoranjan Varshney, Mehar Aziz, Mohammad Shahid, Mahfooz Basha, Kavita Gaur. Unusual presentation of more common disease/injury Kaposi sarcoma presenting as dermal nodule. BMJ Case Reports 2011; doi: 10.1136/bcr.01.2011.3789.
19. Konrad Wroński1, Przemysław Stefaniak, Zbigniew Masłowski, Leszek Frąckowiak. Cutaneous Kaposi sarcoma– case report. New Med 2015; 19 (3): 92-93 DOI: 10.5604/14270994.1179841.
20. Ana Isabel Teixeira, Miguel Neno, Robert Badura, João Borges-Costa, Paulo Leal Filipe. Kaposi Sarcoma of the eyelid as an initial manifestation of AIDS. Dermatology Online Journal 22 (7): 12.
21. La Ferla L, Pinzone MR, Nunnari G, Martellotta F, Lleshi A, Tirelli U, De Paoli P, Berretta M, Cacopardo B. Kaposi' s sarcoma in HIV-positive patients: the state of art in the HAART-era. Eur Rev Med Pharmacol Sci. 17 (17): 2354-65 2013 [PMID 24065230].
22. Agaba P, Sule H, Ojoh R et al. Poor immune status and systemic disease are independently associated with mortality in AIDS-related Kaposi Sarcoma in Nigeria. Infect Agents Cancer. 7 (Suppl 1): P7, 2012 [PMC3330062].
23. Di Lorenzo G, Konstantinopoulos PA, Pantanowitz L, Di Trolio R, De Placido S, Dezube BJ, Management of AIDS-related Kaposi’s sarcoma, Lancet Oncol. 8 (2): 167-76, 2007 [PMID 17267331].