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High Lipoprotein (a) Concentration Is Associated with Diabetic Nephrophaty

Aims: Lipoprotein (a) [Lp(a)] has been well recognized as a risk factor for both micro and macrovascular complications in diabetes, due to its atherogenic effects. Studies suggested that serum lipoprotein (a) [Lp(a)] concentration may take part in the aggravation of diabetic nephropathy. Accumulating evidence suggests that higher serum Lp(a) may be associated with impaired renal function in populations. Therefore this study comprehensively evaluates the association between Lipoprotein (a) and diabetic nephropathy in patients with type 2 diabetes mellitus. Methods: One hundred subjects (50 with diabetic nephrophaty and 50 type 2 diabetes mellitus without nephrophaty) were studied. The examination used blood serum where lipoprotein a used the ELISA method. Nonpara- metric Mann–Whitney U-tests were used to compare the levels of lipoprotein a in diabetic nephrophaty and Type 2 DM without diabetic nephropathy. Results: Lipoprotein a in the diabetic nephropathy group was higher when compared to the type 2 DM group without nephropathy (OR = 2.8; 95%; CI = 1.84-12.07). Conclution: High lipoprotein (a) concentration are associated with diabetic nephrophaty. Lipoprotein may reflect chronic underlying pathophysiological processes involved in development of complications of T2DM and serum Lp(a) can be considered as a promising predictive factor for the diagnosis of earlier diabetic nephropathy.

Lipoprotein (a), Diabetic Nephrophaty, Type 2 Diabetes Mellitus

APA Style

Meutia Atika Faradilla, Karina Shasri Anastasya, Yohana, Meiyanti, Andira Larasari, et al. (2023). High Lipoprotein (a) Concentration Is Associated with Diabetic Nephrophaty. International Journal of Diabetes and Endocrinology, 8(3), 37-41.

ACS Style

Meutia Atika Faradilla; Karina Shasri Anastasya; Yohana; Meiyanti; Andira Larasari, et al. High Lipoprotein (a) Concentration Is Associated with Diabetic Nephrophaty. Int. J. Diabetes Endocrinol. 2023, 8(3), 37-41. doi: 10.11648/j.ijde.20230803.11

AMA Style

Meutia Atika Faradilla, Karina Shasri Anastasya, Yohana, Meiyanti, Andira Larasari, et al. High Lipoprotein (a) Concentration Is Associated with Diabetic Nephrophaty. Int J Diabetes Endocrinol. 2023;8(3):37-41. doi: 10.11648/j.ijde.20230803.11

Copyright © 2023 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License ( which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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