Using time domain reflectometry (TDR) at varying concentrations, the dielectric analysis of aqueous Polyvinylpyrrolidone (PVP) (K-30) and in the presence of medication-Ibuprofen (IBP) has been conducted in the frequency range of 0.01 GHz to 30 GHz at temperature 298.15 K. Complex dielectric permittivity was described using the Harviliak-Negami equation. Using the Cole-Cole model, the dielectric permittivity spectra and relaxation behavior of aqueous PVP and aqueous PVP + IBP were examined. Two relaxation peaks can be seen in the acquired dielectric spectra. High-frequency relaxation is ascribed to the reorientation of solvent molecules, whereas low-frequency relaxation is caused by the dominating interactions between solute molecules. Dielectric parameters have been used to analyze the dynamical and structural characteristics of solute molecules and drugs in solvent, including the complex permittivity spectra (ε*), static dielectric constant (εj), and relaxation time (τj).
| Published in | Abstract Book of the National Conference on Advances in Basic Science & Technology |
| Page(s) | 98-98 |
| Creative Commons |
This is an Open Access abstract, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Polyvinylpyrrolidone (PVP), Cole-Cole Model, Dielectric Constant
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