Research Article
Serum Transthyretin Profile in Patients with Chronic Renal Failure on Hemodialysis at Souro Sanou University Hospital in Bobo-Dioulasso
Arnaud Kouraogo,
Ollo Da,
Aoua Semdé,
Alice Kiba,
Fabienne Soudre,
Raoul Karfo,
Amidou Sawadogo,
Emmanuel Zongo,
Fatou Gueye Tall,
Abdoul Salam Ouédraogo,
Sanata Bamba,
Georges Anicet Ouédraogo,
Elie Kabre,
Jean Sakande
Issue:
Volume 11, Issue 4, December 2023
Pages:
47-52
Received:
13 September 2023
Accepted:
7 October 2023
Published:
31 October 2023
Abstract: Introduction: Transthyretin (prealbumin) is a protein secreted by the liver that is involved in the assessment of undernutrition and nutritional intake. Undernutrition in hemodialysis patients is associated with a worsening of vital prognosis. The main objective of this study was to investigate the transthyretin profile in hemodialysis patients with chronic kidney disease (CKD) in the absence of inflammation in Bobo-Dioulasso, Burkina Faso. Material and methods: This was a prospective study of CKD hemodialysis patients recruited at the CHU-SS from 1er January 2022 to 28 February 2022. Socio-demographic data were obtained after examination of the medical records of hemodialysis CKD patients. All biochemical parameters were measured on the COBAS® 6000 automated system. Colorimetric methods were used to measure urea (urease/Glutamate dehydrogenase), creatinine (modified Jaffé) and albumin (bromocresol green). CRP, alpha-1-glucoprotein acid and transthyretin were determined by the immunoturbidimetric method. Results and discussion: A total of 41 hemodialysis patients were included in the study. The mean age was 42.93±12.21 years with extremes ranging from 22 to 72 years. There was a male predominance with a sex ratio (M/F) of 1.56. The mean BMI of the patients was 20.70±2.87 kg/m2 with extremes from 14.45 to 28.28 kg/m2. Mean transthyretin was 0.47±0.13 g/L. Significant positive correlations were observed with albumin (r=0.77; p=0.0000) and alpha 1 glycoprotein acid (r=0.43; p= 0.004). In the absence of inflammation in the patient group, only one patient (2.44%) presented with hypotranthyretinemia. Conclusion: Transthyretin provides quantitative and clinically useful data for better management of undernutrition and, above all, for predicting the morbidity and mortality associated with protein-energy undernutrition.
Abstract: Introduction: Transthyretin (prealbumin) is a protein secreted by the liver that is involved in the assessment of undernutrition and nutritional intake. Undernutrition in hemodialysis patients is associated with a worsening of vital prognosis. The main objective of this study was to investigate the transthyretin profile in hemodialysis patients wit...
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Research Article
Response of Mung Bean (Vignaradiata L.) Varieties to Phosphorus Fertilizer Rates Under Irrigation Condition
Eyaya Tigabie Shiferaw,
Damtew Abewoy*
Issue:
Volume 11, Issue 4, December 2023
Pages:
53-66
Received:
17 November 2023
Accepted:
4 December 2023
Published:
14 December 2023
Abstract: The field experiment was conducted during 2018/19 cropping season at Gewane Afar region of Ethiopia to identify well adapted and high yielding varieties, determine optimum and assess cost-benefit of phosphorus fertilizer rates for production of mung bean. Treatments studied consisted of factorial combinations of three improved mung bean varieties and one local varieties (Boreda, NVL-I, Rasa and Showa robit respectively) and four phosphorus rates (10, 20, 30 and 40 kg P ha-1) laid out in Randomized Complete Block Design with three replications. The results showed that the highest effect of 40 kg P ha-1 on plant height (45.03 cm), primary branch (5.64), secondary branch (6.5), total number of nodules (8.0), hundred seed weight (4.77g) and aboveground dry biomass (5.08 t). The interaction effect of varieties and phosphorus rate also significantly influenced 50% flowering, 90% physiological maturity, number of pod plant-1, number of seed pod-1 and grain yield. The highest days to flowering (45 days) and days to maturity (74.15 days) were recorded from variety Rasa with 10 kg P ha-1 whereas, the highest numbers of pods plant-1 (28.5), number of seed pods-1(10.8) and grain yield (1.54 t) were recorded from the combination of variety Boreda with 30 kg P ha-1, which was statistically at par with that from variety Boreda with 40 kgP ha-1. Whereas the lowest grain yield (0.72 t ha-1) was obtained from the application of 10 kg P ha-1 with variety NVL-1. The results of partial budget analysis showed that application of 30 kg Pha-1 with variety Boreda gave marginal rate of return above the minimum acceptable values with additional investment advantage for the future. Among the combinations of varieties with P fertilizer rates, variety Boreda with 30 kg P ha-1 had showed acceptable marginal rate of returns (262%) and generated the highest net benefit (31,493 birr). Hence it can be concluded that use of 30 kg P ha-1with variety Boreda can be used to enhance the yield and profitability of mung bean production at Gewane and areas with similar agro-ecology. However, the results need to be evaluated and cheeked under different agro climatic conditions and season.
Abstract: The field experiment was conducted during 2018/19 cropping season at Gewane Afar region of Ethiopia to identify well adapted and high yielding varieties, determine optimum and assess cost-benefit of phosphorus fertilizer rates for production of mung bean. Treatments studied consisted of factorial combinations of three improved mung bean varieties a...
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