International Journal of Ophthalmology & Visual Science

Special Issue

The Relation Between Age Related Macular Degeneration and Thyroid Disorders

  • Submission Deadline: May 20, 2020
  • Status: Submission Closed
  • Lead Guest Editor: Mona Abdelkader
About This Special Issue
Age related macular degeneration (ARMD) is one of the causes of visual loss worldwide and increasing in prevalence. The pathophysiology of ARMD is complex. Drusen is initiated by inflammatory cells and activated by complement formation while the cause of pigment alteration is still unclear. Thyroid hormones regulate different visual functions. Human retinal pigment epithelial (RPE) cells express thyroid hormone receptors that are target for thyroid hormone. Suppression of thyroid hormone preserves cone photoreceptors in mouse with retinal degeneration. While, administration of active thyroid hormone deteriorates cones.
Thyroid dysfunctions are common, with prevalence up to 10%. Thyroid disorders are associated with alterations in lipid levels, atherosclerosis, and hypertension which are predisposing factors for ARMD development. Some studies have shown that the use of thyroid hormones is associated with AMD while another study did not establish such relationship.
The purpose of the special issue is to determine the relation between thyroid disorders and thyroid hormones and ARMD.

Aims and Scope:

  1. T3
  2. T4
  3. Tsh
  4. Armd (Age Related Macular Degeneration)
  5. Hyperthyroidism
  6. Hypothyroidism
Lead Guest Editor
  • Mona Abdelkader

    Assistant Professor in Ophthalmic Center, Mansoura University, Mansoura, Egypt

Guest Editors
  • Naglaa Abass

    Mansoura Medicine Hospital, Mansoura, Egypt

Published Articles
  • The Relation Between Age Related Macular Degeneration and Thyroid Disorders

    Mona Abdelkader , Naglaa Abass

    Issue: Volume 4, Issue 4, December 2019
    Pages: 101-105
    Received: Sep. 16, 2019
    Accepted: Oct. 18, 2019
    Published: Nov. 20, 2019
    DOI: 10.11648/j.ijovs.20190404.18
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    Abstract: The Purpose of the study was to evaluate the association between thyroid -stimulating hormone (TSH), free tri-iodothyronine (T3), free thyroxine (T4), hypothyroidism, hyperthyroidism and age related macular degeneration (ARMD) incidence. Nine hundred and fifty patients with thyroid disorders versus five hundred and thirty eu-thyroid subjects were i... Show More