Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery

Maksimovich Yelizaveta

doi:doi:10.11648/j.wjmcr.20250601.11

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Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery

Maksimovich Yelizaveta^*

Published in World Journal of Medical Case Reports (Volume 6, Issue 1)

Received: 24 December 2024 Accepted: 16 January 2025 Published: 21 March 2025

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Abstract

Reconstructive heart surgeries, like coronary artery bypass grafting (CABG), carry a risk of significant complications, including death. These complications encompass a range of cardiovascular issues, including CABG-related myocardial infarction, worsening heart failure, arrhythmias. This study aimed to develop a method for predicting these early postoperative complications in patients undergoing CABG. The prediction model was based on the relationship between hemolysis, changes in iron levels, markers of oxidative stress, and nitric oxide levels. The study's approach draws upon earlier investigations, which looked at the relationship between complications following CABG and: intraoperative hemolysis, changes in iron transport and storage, oxidative stress levels, and stable nitric oxide metabolites. This research built on that foundation to create a more comprehensive understanding and prediction method. This study employed a multi-faceted approach to investigate the relationship between intraoperative hemolysis and the development of early postoperative cardiac complications after CABG. A total of 123 patients with coronary artery disease (CAD), who underwent CABG, were categorized into three groups based on the degree of IOH, measured by free hemoglobin (Hb) levels in blood plasma at the conclusion of the CABG procedure using a Неmo Cue Plasma/Low Hb analyzer. Groups were: no significant intraoperative hemolysis (n=43), low intraoperative hemolysis (n=42), and high intraoperative hemolysis (n=38).

Published in	World Journal of Medical Case Reports (Volume 6, Issue 1)
DOI	10.11648/j.wjmcr.20250601.11
Page(s)	1-4
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Bypass Grafting, Oxidative, Complications, Iron, Nitric Oxide, Hemolysis

References

[1]	Adelborg, K. Thirty-year mortality after coronary artery bypass graft surgery: a Danish nationwide population-based cohort study / K. Adelborg, E. Horváth-Puhó, M. Schmidt, et al. // Circ. Cardiovasc. Qual. Outcomes. 2017. V. 10. P. 1-9.
[2]	Åström A. Risk of ischemic stroke after acute myocardial infarction in patients undergoing coronary artery bypass graft surgery / Åström A., Söderström L., Mooe T. // Scientific Reports. 2020. V. 10. №. 1. P. 1-9.
[3]	Bagheri F. et al. Reactive oxygen species-mediated cardiac-reperfusion injury: mechanisms and therapies/ Bagheri F. et al. // Life sciences. 2016. Т. 165. P. 43-55.
[4]	Bi Y. et al. Dysregulation of iron metabolism in cardiovascular diseases: From iron deficiency to iron overload / Bi Y. et al. // Biochemical Pharmacology. 2021. V.190. P. 114-661.
[5]	Maksimovich Ye. Early complications after coronary bypass operation/ Maksimovich Ye., Chmara N.// Abstr. the 16^th International congress of medical sciences (ICMS) for students and young doctors 11-14 May 2017. Bulgaria. P. 254.
[6]	Afrasiabirad, A. On-pump beating coronary artery bypass in high risk coronary patients/ A. Afrasiabirad, N. Safaie, H. Montazergaem // Iran J. Med. Sci. 2015. V. 40. P. 40-44.
[7]	Cavalcante, R. Outcomes after percutaneous coronary intervention or bypass surgery in patients with unprotected left main disease/ R. Cavalcante, Y. Sotomi, C. W. Lee, J. M. Ahn, V. Farooq, H. Tateishi // J. Am. Coll. Cardiol. 2016. V.68. P. 999-1009.
[8]	Bagheri F. et al. Reactive oxygen species-mediated cardiac-reperfusion injury: mechanisms and therapies/ Bagheri F. et al. // Life sciences. 2016. Т. 165. P. 43-55.
[9]	Bi Y. et al. Dysregulation of iron metabolism in cardiovascular diseases: From iron deficiency to iron overload / Bi Y. et al. // Biochemical Pharmacology. 2021. V. 190. P. 114-661.
[10]	Chikwe, J. Long-term outcomes after off-pump versus on-pump coronary artery bypass grafting by experienced surgeons / Chikwe J., Lee T., Itagaki S. et al. // J. Am. Coll Cardiol. 2018. V. 72. P.1478-1486.
[11]	Maksimovich, Ye. N. Endothelial vasoactive properties in patients after coronary artery bypass surgery with different level of hemolysis / Ye. N. Maksimovich, T. P. Pronko: abstract // Pathophysiology, 2018. Vol. 25(3). P. 177.
[12]	Maksimovich, Ye. N. Association of hemolysis with the incidence of heart rhythm disturbances following coronary artery bypass graft surgery/ Ye. N. Maksimovich, T. P. Pronko, V. А. Yanushko, Yu. A. Kashcheyeu, V. A. Snezhitski // Journal of Arrhythmology, 2019; 26(2): 29-36. (In Russ) https://doi.org/10.35336/VA-2019-2-29-36
[13]	Maksimovich Y. Nitrites and nitrates concentration in patients with coronary artery bypass/ Maksimovich Y., Stelmakh A., Dubovik A., ChmaraN., Kashcheua Y. // International Scientific Conference SCIENCE4HEALTH 2017 13-15.04.2017 RUDN. University, Moscow, Russia. Р. 137.
[14]	Chikwe, J. Long-term outcomes after off-pump versus on-pump coronary artery bypass grafting by experienced surgeons / Chikwe J., Lee T., Itagaki S. et al. // J. Am. Coll Cardiol. 2018. V. 72. P.1478-1486.
[15]	Daniel, J. F. Improving coronary artery bypass grafting: a systematic review and meta-analysis on the impact of adopting transit-time flow measurement / J. F. Daniel, Thuijs M., Margreet W. A. David P. Taggart // Eur. J. Cardiothorac. 2019. V. 56(4). P. 654-663.

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APA Style

Yelizaveta, M. (2025). Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World Journal of Medical Case Reports, 6(1), 1-4. https://doi.org/10.11648/j.wjmcr.20250601.11

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ACS Style

Yelizaveta, M. Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World J. Med. Case Rep. 2025, 6(1), 1-4. doi: 10.11648/j.wjmcr.20250601.11

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AMA Style

Yelizaveta M. Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World J Med Case Rep. 2025;6(1):1-4. doi: 10.11648/j.wjmcr.20250601.11

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@article{10.11648/j.wjmcr.20250601.11,
  author = {Maksimovich Yelizaveta},
  title = {Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery
},
  journal = {World Journal of Medical Case Reports},
  volume = {6},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.wjmcr.20250601.11},
  url = {https://doi.org/10.11648/j.wjmcr.20250601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20250601.11},
  abstract = {Reconstructive heart surgeries, like coronary artery bypass grafting (CABG), carry a risk of significant complications, including death. These complications encompass a range of cardiovascular issues, including CABG-related myocardial infarction, worsening heart failure, arrhythmias. This study aimed to develop a method for predicting these early postoperative complications in patients undergoing CABG. The prediction model was based on the relationship between hemolysis, changes in iron levels, markers of oxidative stress, and nitric oxide levels. The study's approach draws upon earlier investigations, which looked at the relationship between complications following CABG and: intraoperative hemolysis, changes in iron transport and storage, oxidative stress levels, and stable nitric oxide metabolites. This research built on that foundation to create a more comprehensive understanding and prediction method. This study employed a multi-faceted approach to investigate the relationship between intraoperative hemolysis and the development of early postoperative cardiac complications after CABG. A total of 123 patients with coronary artery disease (CAD), who underwent CABG, were categorized into three groups based on the degree of IOH, measured by free hemoglobin (Hb) levels in blood plasma at the conclusion of the CABG procedure using a Неmo Cue Plasma/Low Hb analyzer. Groups were: no significant intraoperative hemolysis (n=43), low intraoperative hemolysis (n=42), and high intraoperative hemolysis (n=38). 
},
 year = {2025}
}

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TY  - JOUR
T1  - Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery

AU  - Maksimovich Yelizaveta
Y1  - 2025/03/21
PY  - 2025
N1  - https://doi.org/10.11648/j.wjmcr.20250601.11
DO  - 10.11648/j.wjmcr.20250601.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20250601.11
AB  - Reconstructive heart surgeries, like coronary artery bypass grafting (CABG), carry a risk of significant complications, including death. These complications encompass a range of cardiovascular issues, including CABG-related myocardial infarction, worsening heart failure, arrhythmias. This study aimed to develop a method for predicting these early postoperative complications in patients undergoing CABG. The prediction model was based on the relationship between hemolysis, changes in iron levels, markers of oxidative stress, and nitric oxide levels. The study's approach draws upon earlier investigations, which looked at the relationship between complications following CABG and: intraoperative hemolysis, changes in iron transport and storage, oxidative stress levels, and stable nitric oxide metabolites. This research built on that foundation to create a more comprehensive understanding and prediction method. This study employed a multi-faceted approach to investigate the relationship between intraoperative hemolysis and the development of early postoperative cardiac complications after CABG. A total of 123 patients with coronary artery disease (CAD), who underwent CABG, were categorized into three groups based on the degree of IOH, measured by free hemoglobin (Hb) levels in blood plasma at the conclusion of the CABG procedure using a Неmo Cue Plasma/Low Hb analyzer. Groups were: no significant intraoperative hemolysis (n=43), low intraoperative hemolysis (n=42), and high intraoperative hemolysis (n=38). 

VL  - 6
IS  - 1
ER  -

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Author Information

Maksimovich Yelizaveta

Department of Propaedeutics of Internal Medicine, Grodno State Medical University, Grodno, Belarus

Contact Email

http://orcid.org/0000-0002-4344-4432

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Plain Text BibTeX RIS

APA Style

Yelizaveta, M. (2025). Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World Journal of Medical Case Reports, 6(1), 1-4. https://doi.org/10.11648/j.wjmcr.20250601.11

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ACS Style

Yelizaveta, M. Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World J. Med. Case Rep. 2025, 6(1), 1-4. doi: 10.11648/j.wjmcr.20250601.11

Copy | Download

AMA Style

Yelizaveta M. Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery. World J Med Case Rep. 2025;6(1):1-4. doi: 10.11648/j.wjmcr.20250601.11

Copy | Download

@article{10.11648/j.wjmcr.20250601.11,
  author = {Maksimovich Yelizaveta},
  title = {Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery
},
  journal = {World Journal of Medical Case Reports},
  volume = {6},
  number = {1},
  pages = {1-4},
  doi = {10.11648/j.wjmcr.20250601.11},
  url = {https://doi.org/10.11648/j.wjmcr.20250601.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.wjmcr.20250601.11},
  abstract = {Reconstructive heart surgeries, like coronary artery bypass grafting (CABG), carry a risk of significant complications, including death. These complications encompass a range of cardiovascular issues, including CABG-related myocardial infarction, worsening heart failure, arrhythmias. This study aimed to develop a method for predicting these early postoperative complications in patients undergoing CABG. The prediction model was based on the relationship between hemolysis, changes in iron levels, markers of oxidative stress, and nitric oxide levels. The study's approach draws upon earlier investigations, which looked at the relationship between complications following CABG and: intraoperative hemolysis, changes in iron transport and storage, oxidative stress levels, and stable nitric oxide metabolites. This research built on that foundation to create a more comprehensive understanding and prediction method. This study employed a multi-faceted approach to investigate the relationship between intraoperative hemolysis and the development of early postoperative cardiac complications after CABG. A total of 123 patients with coronary artery disease (CAD), who underwent CABG, were categorized into three groups based on the degree of IOH, measured by free hemoglobin (Hb) levels in blood plasma at the conclusion of the CABG procedure using a Неmo Cue Plasma/Low Hb analyzer. Groups were: no significant intraoperative hemolysis (n=43), low intraoperative hemolysis (n=42), and high intraoperative hemolysis (n=38). 
},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Predicting of Early Cardiovascular Complications After Coronary Artery Bypass Graft Surgery

AU  - Maksimovich Yelizaveta
Y1  - 2025/03/21
PY  - 2025
N1  - https://doi.org/10.11648/j.wjmcr.20250601.11
DO  - 10.11648/j.wjmcr.20250601.11
T2  - World Journal of Medical Case Reports
JF  - World Journal of Medical Case Reports
JO  - World Journal of Medical Case Reports
SP  - 1
EP  - 4
PB  - Science Publishing Group
SN  - 2994-726X
UR  - https://doi.org/10.11648/j.wjmcr.20250601.11
AB  - Reconstructive heart surgeries, like coronary artery bypass grafting (CABG), carry a risk of significant complications, including death. These complications encompass a range of cardiovascular issues, including CABG-related myocardial infarction, worsening heart failure, arrhythmias. This study aimed to develop a method for predicting these early postoperative complications in patients undergoing CABG. The prediction model was based on the relationship between hemolysis, changes in iron levels, markers of oxidative stress, and nitric oxide levels. The study's approach draws upon earlier investigations, which looked at the relationship between complications following CABG and: intraoperative hemolysis, changes in iron transport and storage, oxidative stress levels, and stable nitric oxide metabolites. This research built on that foundation to create a more comprehensive understanding and prediction method. This study employed a multi-faceted approach to investigate the relationship between intraoperative hemolysis and the development of early postoperative cardiac complications after CABG. A total of 123 patients with coronary artery disease (CAD), who underwent CABG, were categorized into three groups based on the degree of IOH, measured by free hemoglobin (Hb) levels in blood plasma at the conclusion of the CABG procedure using a Неmo Cue Plasma/Low Hb analyzer. Groups were: no significant intraoperative hemolysis (n=43), low intraoperative hemolysis (n=42), and high intraoperative hemolysis (n=38). 

VL  - 6
IS  - 1
ER  -

Copy | Download