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Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon

Received: 17 January 2016     Accepted: 1 February 2016     Published: 28 March 2016
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Abstract

Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.

Published in Science Journal of Public Health (Volume 4, Issue 2)
DOI 10.11648/j.sjph.20160402.17
Page(s) 127-131
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Hepatitis B and C, Cameroon, Co-infection

References
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[17] C. Laurent, D. Henzel, C. Mulanga-Kabeya, G. Maertens, B. Larouze, E. Delaporte Seroepidemiological survey of hepatitis C virus among commercial sex workers and pregnant women in Kinshasa, Democratic Republic of Congo Int J Epidemiol, 30 (2001), pp. 872–877.
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    George Mondinde Ikomey, Graeme Brendon Jacobs, Becky Tanjong, Martha Tongo Mesembe, Agnes Eyoh, et al. (2016). Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Science Journal of Public Health, 4(2), 127-131. https://doi.org/10.11648/j.sjph.20160402.17

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    George Mondinde Ikomey; Graeme Brendon Jacobs; Becky Tanjong; Martha Tongo Mesembe; Agnes Eyoh, et al. Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Sci. J. Public Health 2016, 4(2), 127-131. doi: 10.11648/j.sjph.20160402.17

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    AMA Style

    George Mondinde Ikomey, Graeme Brendon Jacobs, Becky Tanjong, Martha Tongo Mesembe, Agnes Eyoh, et al. Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon. Sci J Public Health. 2016;4(2):127-131. doi: 10.11648/j.sjph.20160402.17

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  • @article{10.11648/j.sjph.20160402.17,
      author = {George Mondinde Ikomey and Graeme Brendon Jacobs and Becky Tanjong and Martha Tongo Mesembe and Agnes Eyoh and Emilia Lyonga and Ebot Mfoataw and Rose Ngoh and Cynthia Raissa Tamandjou and Greg Ikomey and Marie Claire Okomo Assoumou},
      title = {Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon},
      journal = {Science Journal of Public Health},
      volume = {4},
      number = {2},
      pages = {127-131},
      doi = {10.11648/j.sjph.20160402.17},
      url = {https://doi.org/10.11648/j.sjph.20160402.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20160402.17},
      abstract = {Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.},
     year = {2016}
    }
    

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  • TY  - JOUR
    T1  - Evidence of Co and Triple Infections of Hepatitis B and C Amongst HIV Infected Pregnant Women in Buea, Cameroon
    AU  - George Mondinde Ikomey
    AU  - Graeme Brendon Jacobs
    AU  - Becky Tanjong
    AU  - Martha Tongo Mesembe
    AU  - Agnes Eyoh
    AU  - Emilia Lyonga
    AU  - Ebot Mfoataw
    AU  - Rose Ngoh
    AU  - Cynthia Raissa Tamandjou
    AU  - Greg Ikomey
    AU  - Marie Claire Okomo Assoumou
    Y1  - 2016/03/28
    PY  - 2016
    N1  - https://doi.org/10.11648/j.sjph.20160402.17
    DO  - 10.11648/j.sjph.20160402.17
    T2  - Science Journal of Public Health
    JF  - Science Journal of Public Health
    JO  - Science Journal of Public Health
    SP  - 127
    EP  - 131
    PB  - Science Publishing Group
    SN  - 2328-7950
    UR  - https://doi.org/10.11648/j.sjph.20160402.17
    AB  - Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97 (11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1, 17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%)) (95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.
    VL  - 4
    IS  - 2
    ER  - 

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Author Information
  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa

  • Faculty of Health Sciences, University of Buea, Buea, Cameroon

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Faculty of Health Sciences, University of Buea, Buea, Cameroon

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

  • Center for the Study and Control of Communicable Diseases (CSCCD), Department of Microbiology, Haematology, Parasitology and Infectious Diseases of Medicine, University of Yaoundé, Yaounde, Cameroon

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