Acute renal failure (ARF) is a major public health problem, with incidence in newborns and children ranging from 4.5 to 82%, and mortality from 19 to 83%. The aim was to determine the frequency of acute renal failure in children admitted to the pediatric ward of the Hospital National Ignace Deen. Patients and Method: This was a dynamic descriptive study covering the period from April 1er to September 30 2023; children under 16 years of age with a sudden rise in creatinine above 1.6 mg/dl were included in the study. Results: The incidence of acute renal failure was 7.93%; mean age 8.04 ±3 years. The sex ratio was 2 in favor of men. Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor (91.67%, 66.67%, 58.33% and 56.25% respectively); proteinuria, hematuria and biluribinuria were found at Urine Test Strip (BU) (54.17%, 29.17% and 41.67% respectively). Stage I ARF predominated, at 52.02%; organic ARF was found in 54.10% of cases. Mortality in this series was 14.58%. Conclusion: the management of pediatric renal failure at the complication stage is currently a major problem for healthcare professionals, due to the lack of nephropediatric services or specialized centers for extra-renal purification in the various health facilities in Guinea.
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Acute renal failure (ARF) is a major public health problem, defined as a sudden deterioration in renal function resulting in elevated creatinine levels, an inability of the kidneys to excrete waste products of nitrogen metabolism and to maintain the body's hydromineral balance
[1]
Tschumi S, Caccia J, Wagner S, Schläpfer TR. Acute renal failure in children. Paediatrica. 31(04) 2020; 30-35.
[2]
Samaké M, Sy S, Yattara H, Fofana AS, Coulibaly M, Diallo D, et al. Prevalence and Prognosis of Acute Renal Failure at the Fousseyni Daou Hospital in Kayes. Health Sci Dis. May 2020 21(5) 15-20.
[3]
Hasina RS. Risk Factors For Neonatal Acute Renal Failure [Mémoire N°484-2021]. Antananarivo: Faculté de médecine 85p.
; The incidence of ARF in newborns and children ranges from 4.5 to 82%, with a mortality of 19 to 83%; it is also a burden on the healthcare system, leading to increased treatment costs associated with drugs and Extra Renal Purification (EER)
[5]
Folkestad T, Brurberg KG, Nordhuus KM, Tveiten CK, Guttormsen AB, Os I, et al. Acute kidney injury in burn patients admitted to the intensive care unit: a systematic review and meta-analysis. Crit Care. 2020; 24(2): 11p
Torgeir F, Brurberg KG, Nordhuus KM, Tveiten CK, Guttormsen AB, Os I, et al. Acute kidney injury in burn patients admitted to the intensive care unit: a systematic review and meta-analysis. Crit Care. 2020; 24(1): 2p.
Gallo D, Bijl-Marcus KA de, Alderliesten T, Lilien M, Groenendaal F. Early Acute Kidney Injury in Preterm and Term Neonates: Incidence, Outcome, and Associated Clinical Features. NEO. 2021; 118(2): 9-174.
. Acute renal failure complicated by cardiovascular disease is a major cause of morbidity and mortality in pediatric intensive care units
[9]
Batouche DD, Batouche K, Bounoua F, Boumendil D: Prognostic factors of cardiovascular involvement during severe acute renal failure in children in intensive care. Néphrologie &Thérapeutique 16(5) Septembre 2020 p 272-273.
The etiologies of ARF in the pediatric setting are diverse, the circumstances of discovery variable; it is the consequence of a low glomerular filtration rate (GFR), high renal vascular resistance, low perfusion of the cortical region; high tubular sodium excretion and a hemolytic syndrome
[10]
Rambeloson SH, Samena C, Rabevazaha NA, Rakotojoelimaria EH, Robinson AL. Risk factors for acute neonatal renal failure. International Journal of Contemporary Pediatrics. 26 Sep 2022; 9(10): 9405.
Matuszkiewicz-Rowińska, Joanna, Małyszko, Jolanta. Acute kidney injury in critically ill newborns: What do we know? What do we need to learn? Crit care. 2022; 24(1): 2p.
[12]
Danka Pokrajac¹, Admir Hadzimuratovic, Aida Mustajbegovic-Pripoljac, Verica Misanovic, Dusko Anic, Sajra UzicaninThe Causes of Acute Kidney Injury in Critically Ill Children Who Needs Renal Replacement Therapy ME ARCH. 2022 APR; 76(2): 90-95.
Acute tubular necrosis (ATN) remains the predominant etiology of ARF in pediatric intensive care; prognosis is closely linked to very young age and ARF associated with sepsis
[10]
Rambeloson SH, Samena C, Rabevazaha NA, Rakotojoelimaria EH, Robinson AL. Risk factors for acute neonatal renal failure. International Journal of Contemporary Pediatrics. 26 Sep 2022; 9(10): 9405.
Karray R, Jamoussi A, Ayed S, Lakhdhar D, Rachdi E, Khelil J, et al. Surmortality of oligoanuric acute renal failure during COVID-19: a prospective Tunisian study. Nephrology & Therapeutics. 2020; 16. 312. InterNet links.
The onset of acute renal failure can rapidly lead to life-threatening hydroelectrolytic disorders, with the risk of acute lung oedema due to hydrosodium overload, and cardiac rhythm disorders due to hyperkalemia
[14]
Batouche DD; Benrachel-Taleb F; Bakri SA; Sadouk H; Menaouri M; Mohammedi S; et al; Acute renal failure in pediatric intensive care: etiological circumstance and prognostic factors. Néphrologie & Thérapeutique 17(5) Septembre 2021; 382.
. Its discovery should therefore lead to the immediate introduction of symptomatic treatment to prevent these complications, and the search for a cause that may require specific treatment
[13]
Karray R, Jamoussi A, Ayed S, Lakhdhar D, Rachdi E, Khelil J, et al. Surmortality of oligoanuric acute renal failure during COVID-19: a prospective Tunisian study. Nephrology & Therapeutics. 2020; 16. 312. InterNet links.
Today, thanks to the development of resuscitation techniques and EER, including in neonates and premature infants, and to early management, the preserved mortality of ARF is no longer related to renal damage but to the severity of associated damage
[15]
Macher MA, Acute renal failure in children: ECM-Pediatrics, 1(1) February 2004, 73-78
The aim of this study was to investigate the frequency and describe the clinical and prognostic aspects of acute renal failure in the Pediatric Department of the Ignace Deen National Hospital. Due to the lack of pediatric dialysis in the country, the importance of this study was to alert decision-makers to the mortality of this pathology in children, and to put in place preventive measures.
2. Methodology
This was a dynamic descriptive study covering the period from April 1er to September 30 2023; recruitment was exhaustive and included all patients admitted to the department during the study period. Children under 16 years of age with impaired renal function due to creatinine elevation above 1.6 mg/dl were included in the study; creatinine clearance was calculated using the Schwartz method. Several creatinine determinations were performed; baseline creatinine levels were determined on patient admission, and ARF was classified according to Kidney Disease Improving Global Outcomes (KDIGO) recommendations. Acute renal failure was considered on clinical grounds: absence of normocytic normochromic anemia, absence of history of renal failure, normal kidney size on ultrasound. Types of acute renal failure were divided into functional ARF in the presence of signs of extra-renal dehydration, hypovolemia with a normal BU; organic ARF in the presence of at least one BU abnormality: Pu and/or Hu, Leukocyturia in the absence of urinary tract infection. Obstructive ARF in the presence of unilateral or bilateral dilatation of the urinary tract on abdominal ultrasound. Analysis was performed in SPSS v21.
3. Results
The incidence of acute renal failure in this series was 7.93% (Figure 1).
The 5 to 10 age group was the most dominant, i.e. 70.8%, with an average age of 8.04 ± 3 years (Table 1).
Male predominance, with a sex ratio of 2 (Figure 2)
Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor, with frequencies of 91.67%, 66.67%, 58.33% and 56.25% respectively (Table 2).
Proteinuria, Hematuria and leukocyturia on dipstick were 54.17%, 29.17% and 27% respectively (Table 3).
Biological assessment: all patients had creatinine levels above 1.6 mg/dl, anemia was present in 72.92% (Table 4).
Stage I ARF according to KDIGO 2012 was the most represented 52.08% followed by stage II 31.25% (Table 5).
Organic ARF was the most common form, accounting for 54.17% (Figure 3)
Progression was marked by an 85.42% recovery rate of normal renal function with a mortality rate of 14.58% (Figure 4).
Figure 2. Gender distribution of children with ARF in the pediatric ward of the Hôpital National Ignace Deen, Conakry.
Table 2. Distribution of children with ARF in the Pediatrics Department of the Hôpital National Ignace Deen, Conakry, according to clinical signs.
Clinical signs
Workforce
Percentage
Reasons for consultation
Fever
44
91,67
Physical asthenia
32
66,67
Anorexia
28
58,33
Headaches
24
50
Vomiting
22
45,83
Diarrhea
8
16,67
Physical signs
Permanent dyspnea
21
43,75
Anuria
5
10,42
Edema
3
6,25
Pale Conjunctiva
27
56,25
Persistent skin folds
16
33,33
Table 3. Distribution of children with ARF in the pediatric ward of the Hôpital National Ignace Deen, Conakry, by BU result.
Urine dipstick (UD)
Workforce
Percentage
Proteinuria
26
54,17
Hematuria
14
29,17
Leukocyturia
12
25,00
Glucosuria
6
12,50
Bilirubinuria
20
41,67
Urine density > 1020
15
31,25
Table 4. Distribution of children with ARF in the pediatric ward of the Hôpital National Ignace Deen, Conakry, according to biological status.
Biological parameters
Workforce
Percentage
Creatinine > 1.6 mg/dl
48
100
Urea > 52 mg/dl
36
75
Hb <8 g/dl
35
72,92
Reticulocytes> 25 G/L
48
100
Hyponatremia 125 to 135 mmol/l
15
31,25
Calcemia 8.6 to 10.3 mg/dl
45
93,75
Table 5. Distribution of children with AKI in the pediatric ward of the Ignace Deen National Hospital in Conakry according to the stage of acute renal failure according to KDIGO 2012.
Figure 4. Distribution of children with ARF in the pediatric ward of the Hospital National Ignace Deen, Conakry, according to course.
4. Discussion
The actual frequency of pediatric ARF is not well known, due to the paucity of studies; in this study, more than 7 out of 10 patients (7/10) presented with acute renal failure.
Akoly et al in Togo in 2019, Xu et Coll in China in 2018 and Maïga et Coll in 2018 in Chad had found respective frequencies of 4%; 13% and 5.81%
[16]
Akoly DAE, Tsevi YM, FjadouEK, Guedenon KM, Amekoudi EYM, Tsolenyanu E et al, Etiological and evolving profile of renal disability of children in hospital in Togo. Nephrology Therapeutics Nov 2019; 15(6): 448-451.
Xu X, Nie S, Zhang A, Mao J, Liu HP, Xia H, et al. Acute Kidney Injury among Hospitalized Children in China. Clin J Am Soc Nephrol. 2018; 13(12): 1791–1800.
Maïga Z, Moussa Tondi ZM, Moumini G, Mahamat Abderraman G, Hamat I, Hassane DM et al, Insuffisance rénale des enfants de 0 à 15 ans: Etude multicentrique. Revue scientifique du Tchad; serie B, 2016
The 5-10 age group accounted for nearly 3 out of 4 patients, with an average age of 8 ± 3 years.
Akoly et al in 2019 in Togo found a mean age of 8.17 years
[16]
Akoly DAE, Tsevi YM, FjadouEK, Guedenon KM, Amekoudi EYM, Tsolenyanu E et al, Etiological and evolving profile of renal disability of children in hospital in Togo. Nephrology Therapeutics Nov 2019; 15(6): 448-451.
. Moussa Tondi et al found a mean age of 2.5± 0.75 years, with a predominance of the [0 - 5 years] age group (43%)
[19]
Moussa Tondi ZM, Moussa HD, Garba MD, Abdou I, Salamatou N. Acute renal failure during severe childhood malaria: Experience of pediatric departments in Niamey city hospitals (Niger). Nephrology and Therapeutics September 2017 13(5), 361-362
Male predominance has not been reported as a phenomenon in the literature; Maïga et al in 2018 in Chad found a sex ratio of 1.63
[18]
Maïga Z, Moussa Tondi ZM, Moumini G, Mahamat Abderraman G, Hamat I, Hassane DM et al, Insuffisance rénale des enfants de 0 à 15 ans: Etude multicentrique. Revue scientifique du Tchad; serie B, 2016
Clinical signs were marked by fever in 7 out of 8 patients; physical asthenia in 2 out of 3 patients; and anuria in 1 out of 10 patients.
The manifestation of AKI in children is not specific to this pathology, and clinical signs depend on the etiology responsible. The literature review reports that fever remains the primary reason for consultation during severe malaria associated with acute renal failure
[19]
Moussa Tondi ZM, Moussa HD, Garba MD, Abdou I, Salamatou N. Acute renal failure during severe childhood malaria: Experience of pediatric departments in Niamey city hospitals (Niger). Nephrology and Therapeutics September 2017 13(5), 361-362
. According to KEITA et al in Senegal in 2016, clinical signs were dominated by anemia 68%, vomiting 58%, fever 28%, anuria 22%
[20]
Keita Y. Acute renal failure in children: diagnostic, therapeutic, evolutionary and prognostic. Aspects about 50 college case in the Pediatrics Department in Dakar. Revue africaine et Malgache de recherche scientifique/science de la santé. 2016, 3(2).
[20]
.
Proteinuria dominated the urine dipstick markers for kidney damage in more than half the patients; nearly 3 out of 10 patients had hematuria, and 1 out of 4 had germ-free leukocyturia after a germ-free urine cytobacteriological examination.
Post-infectious glomerular damage in children has been extensively described in the literature
[9]
Batouche DD, Batouche K, Bounoua F, Boumendil D: Prognostic factors of cardiovascular involvement during severe acute renal failure in children in intensive care. Néphrologie &Thérapeutique 16(5) Septembre 2020 p 272-273.
All patients had elevated creatinine levels in excess of 1.6 mg/dl, and 3 out of 4 patients had uremia levels in excess of 100 mg/dl. More than 2 out of 3 patients had anemia with hemoglobin below 8 g/dl.
More than half the patients were in stage I and 1 in 6 in stage III (severe stage according to the KDIGO 2012 severity criteria). Stage III represents the phase of uremic complications requiring EER management. The lack in the country of an EER technique adapted to children increases the risk of death in the absence of recovery of renal function. Luyindula et al found in their study that dialysis was indicated for 57.1%
[21]
Luyindula L, Akele C, Mulamba JM, Bankoto H, evolution of the clinical profile and evolution of acute renal failure in children less than 5 years of age infected or by severe pa-ludism. Nephrology &Therapeutics 15(5) September 2019; 380-381.
More than half the patients had experienced acute organic renal failure according to the criteria defined in this study, and functional AKI was found in almost 40% of patients.
The etiologies of renal damage in children are many and varied; organic damage is the most widely described in the literature
[13]
Karray R, Jamoussi A, Ayed S, Lakhdhar D, Rachdi E, Khelil J, et al. Surmortality of oligoanuric acute renal failure during COVID-19: a prospective Tunisian study. Nephrology & Therapeutics. 2020; 16. 312. InterNet links.
; BATOUCHE et al. found in their study that acute tubular necrosis was ischemic (17%), toxic (25%) and septic (30%); glomerular damage (19%) and vascular damage (7%) were the main etiologies of acute renal failure in children
[9]
Batouche DD, Batouche K, Bounoua F, Boumendil D: Prognostic factors of cardiovascular involvement during severe acute renal failure in children in intensive care. Néphrologie &Thérapeutique 16(5) Septembre 2020 p 272-273.
Progression was favorable in 4 out of 5 patients, with a mortality rate of 14.58%. In their study, Moussa Tondi et al found a favorable outcome with total recovery of renal function in 74%; progression to chronicity was found in 4% and mortality in 11%
[19]
Moussa Tondi ZM, Moussa HD, Garba MD, Abdou I, Salamatou N. Acute renal failure during severe childhood malaria: Experience of pediatric departments in Niamey city hospitals (Niger). Nephrology and Therapeutics September 2017 13(5), 361-362
Conclusion: Acute organic renal failure remains the most common form of ARF in children. The advanced stage of acute renal failure continues to have a poor vital prognosis for children in Guinea, due to the lack of extra-renal purification techniques and appropriate resuscitation. Prevention through malaria control and reduction of Otto Rhino Laryngology and skin infections will reduce the frequency of acute renal failure in children.
Recommendations:
A request to develop the means and techniques for caring for children suffering from renal failure by setting up a nephropediatrics unit, a peritoneal dialysis unit or hemodialysis.
Prevention through the fight against infectious diseases such as malaria, early treatment of Otto Rhino Laryngology and skin infections, and congenital malformations of the urinary tract. Develop investigative resources for the early diagnosis of renal pathologies in children.
Abbreviations
ARF
Acute Renal Failure
AKI
Acute Kidney Injury
ATN
Acute Tubular Necrosis
GFR
Glomerular Filtration Rate
ATCD
Past History
BU
Urine Test Strip
KDIGO
Kidney Disease Improving Global Outcomes
EER
Extra Renal Purification
Coll
Collaborators
g/dl
Gramme per Decilitre
mg/dl
Milligram per Deciliter
mmol/l
Millimole per Liter
µmol/l
Micromole per Liter
Acknowledgments
With this article, we would like to thank our dear master, professor Mohamed Lamine Kaba, for his efforts to improve the scientific quality of this work and his contribution to the supervision and correction of this manuscript.
Declaration of Informed Consent
All authors appearing in this article equally share and agree to the publication of this article in your journal.
Conflicts of Interest
The authors declare no conflicts of interest. This manuscript is to be used for the benefit of science, not for sale.
References
[1]
Tschumi S, Caccia J, Wagner S, Schläpfer TR. Acute renal failure in children. Paediatrica. 31(04) 2020; 30-35.
[2]
Samaké M, Sy S, Yattara H, Fofana AS, Coulibaly M, Diallo D, et al. Prevalence and Prognosis of Acute Renal Failure at the Fousseyni Daou Hospital in Kayes. Health Sci Dis. May 2020 21(5) 15-20.
[3]
Hasina RS. Risk Factors For Neonatal Acute Renal Failure [Mémoire N°484-2021]. Antananarivo: Faculté de médecine 85p.
Folkestad T, Brurberg KG, Nordhuus KM, Tveiten CK, Guttormsen AB, Os I, et al. Acute kidney injury in burn patients admitted to the intensive care unit: a systematic review and meta-analysis. Crit Care. 2020; 24(2): 11p
Torgeir F, Brurberg KG, Nordhuus KM, Tveiten CK, Guttormsen AB, Os I, et al. Acute kidney injury in burn patients admitted to the intensive care unit: a systematic review and meta-analysis. Crit Care. 2020; 24(1): 2p.
Gallo D, Bijl-Marcus KA de, Alderliesten T, Lilien M, Groenendaal F. Early Acute Kidney Injury in Preterm and Term Neonates: Incidence, Outcome, and Associated Clinical Features. NEO. 2021; 118(2): 9-174.
Batouche DD, Batouche K, Bounoua F, Boumendil D: Prognostic factors of cardiovascular involvement during severe acute renal failure in children in intensive care. Néphrologie &Thérapeutique 16(5) Septembre 2020 p 272-273.
Matuszkiewicz-Rowińska, Joanna, Małyszko, Jolanta. Acute kidney injury in critically ill newborns: What do we know? What do we need to learn? Crit care. 2022; 24(1): 2p.
[12]
Danka Pokrajac¹, Admir Hadzimuratovic, Aida Mustajbegovic-Pripoljac, Verica Misanovic, Dusko Anic, Sajra UzicaninThe Causes of Acute Kidney Injury in Critically Ill Children Who Needs Renal Replacement Therapy ME ARCH. 2022 APR; 76(2): 90-95.
Karray R, Jamoussi A, Ayed S, Lakhdhar D, Rachdi E, Khelil J, et al. Surmortality of oligoanuric acute renal failure during COVID-19: a prospective Tunisian study. Nephrology & Therapeutics. 2020; 16. 312. InterNet links.
Akoly DAE, Tsevi YM, FjadouEK, Guedenon KM, Amekoudi EYM, Tsolenyanu E et al, Etiological and evolving profile of renal disability of children in hospital in Togo. Nephrology Therapeutics Nov 2019; 15(6): 448-451.
Xu X, Nie S, Zhang A, Mao J, Liu HP, Xia H, et al. Acute Kidney Injury among Hospitalized Children in China. Clin J Am Soc Nephrol. 2018; 13(12): 1791–1800.
Maïga Z, Moussa Tondi ZM, Moumini G, Mahamat Abderraman G, Hamat I, Hassane DM et al, Insuffisance rénale des enfants de 0 à 15 ans: Etude multicentrique. Revue scientifique du Tchad; serie B, 2016
Moussa Tondi ZM, Moussa HD, Garba MD, Abdou I, Salamatou N. Acute renal failure during severe childhood malaria: Experience of pediatric departments in Niamey city hospitals (Niger). Nephrology and Therapeutics September 2017 13(5), 361-362
Keita Y. Acute renal failure in children: diagnostic, therapeutic, evolutionary and prognostic. Aspects about 50 college case in the Pediatrics Department in Dakar. Revue africaine et Malgache de recherche scientifique/science de la santé. 2016, 3(2).
[21]
Luyindula L, Akele C, Mulamba JM, Bankoto H, evolution of the clinical profile and evolution of acute renal failure in children less than 5 years of age infected or by severe pa-ludism. Nephrology &Therapeutics 15(5) September 2019; 380-381.
Soriba, B., Tégui, C. M. L., Aly, T., Yaya, D. A., Fatoumata, K., et al. (2025). Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Science Journal of Clinical Medicine, 14(1), 1-5. https://doi.org/10.11648/j.sjcm.20251401.11
Soriba, B.; Tégui, C. M. L.; Aly, T.; Yaya, D. A.; Fatoumata, K., et al. Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Sci. J. Clin. Med.2025, 14(1), 1-5. doi: 10.11648/j.sjcm.20251401.11
Soriba B, Tégui CML, Aly T, Yaya DA, Fatoumata K, et al. Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Sci J Clin Med. 2025;14(1):1-5. doi: 10.11648/j.sjcm.20251401.11
@article{10.11648/j.sjcm.20251401.11,
author = {Bangoura Soriba and Camara Mohamed Lamine Tégui and Traore Aly and Diallo Amadou Yaya and Kaba Fatoumata and Barry Kadiatou Mamadou Bobo and Kaba Mohamed Lamine and Bah Alpha Oumar},
title = {Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea)},
journal = {Science Journal of Clinical Medicine},
volume = {14},
number = {1},
pages = {1-5},
doi = {10.11648/j.sjcm.20251401.11},
url = {https://doi.org/10.11648/j.sjcm.20251401.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20251401.11},
abstract = {Acute renal failure (ARF) is a major public health problem, with incidence in newborns and children ranging from 4.5 to 82%, and mortality from 19 to 83%. The aim was to determine the frequency of acute renal failure in children admitted to the pediatric ward of the Hospital National Ignace Deen. Patients and Method: This was a dynamic descriptive study covering the period from April 1er to September 30 2023; children under 16 years of age with a sudden rise in creatinine above 1.6 mg/dl were included in the study. Results: The incidence of acute renal failure was 7.93%; mean age 8.04 ±3 years. The sex ratio was 2 in favor of men. Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor (91.67%, 66.67%, 58.33% and 56.25% respectively); proteinuria, hematuria and biluribinuria were found at Urine Test Strip (BU) (54.17%, 29.17% and 41.67% respectively). Stage I ARF predominated, at 52.02%; organic ARF was found in 54.10% of cases. Mortality in this series was 14.58%. Conclusion: the management of pediatric renal failure at the complication stage is currently a major problem for healthcare professionals, due to the lack of nephropediatric services or specialized centers for extra-renal purification in the various health facilities in Guinea.},
year = {2025}
}
TY - JOUR
T1 - Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea)
AU - Bangoura Soriba
AU - Camara Mohamed Lamine Tégui
AU - Traore Aly
AU - Diallo Amadou Yaya
AU - Kaba Fatoumata
AU - Barry Kadiatou Mamadou Bobo
AU - Kaba Mohamed Lamine
AU - Bah Alpha Oumar
Y1 - 2025/01/17
PY - 2025
N1 - https://doi.org/10.11648/j.sjcm.20251401.11
DO - 10.11648/j.sjcm.20251401.11
T2 - Science Journal of Clinical Medicine
JF - Science Journal of Clinical Medicine
JO - Science Journal of Clinical Medicine
SP - 1
EP - 5
PB - Science Publishing Group
SN - 2327-2732
UR - https://doi.org/10.11648/j.sjcm.20251401.11
AB - Acute renal failure (ARF) is a major public health problem, with incidence in newborns and children ranging from 4.5 to 82%, and mortality from 19 to 83%. The aim was to determine the frequency of acute renal failure in children admitted to the pediatric ward of the Hospital National Ignace Deen. Patients and Method: This was a dynamic descriptive study covering the period from April 1er to September 30 2023; children under 16 years of age with a sudden rise in creatinine above 1.6 mg/dl were included in the study. Results: The incidence of acute renal failure was 7.93%; mean age 8.04 ±3 years. The sex ratio was 2 in favor of men. Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor (91.67%, 66.67%, 58.33% and 56.25% respectively); proteinuria, hematuria and biluribinuria were found at Urine Test Strip (BU) (54.17%, 29.17% and 41.67% respectively). Stage I ARF predominated, at 52.02%; organic ARF was found in 54.10% of cases. Mortality in this series was 14.58%. Conclusion: the management of pediatric renal failure at the complication stage is currently a major problem for healthcare professionals, due to the lack of nephropediatric services or specialized centers for extra-renal purification in the various health facilities in Guinea.
VL - 14
IS - 1
ER -
Soriba, B., Tégui, C. M. L., Aly, T., Yaya, D. A., Fatoumata, K., et al. (2025). Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Science Journal of Clinical Medicine, 14(1), 1-5. https://doi.org/10.11648/j.sjcm.20251401.11
Soriba, B.; Tégui, C. M. L.; Aly, T.; Yaya, D. A.; Fatoumata, K., et al. Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Sci. J. Clin. Med.2025, 14(1), 1-5. doi: 10.11648/j.sjcm.20251401.11
Soriba B, Tégui CML, Aly T, Yaya DA, Fatoumata K, et al. Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea). Sci J Clin Med. 2025;14(1):1-5. doi: 10.11648/j.sjcm.20251401.11
@article{10.11648/j.sjcm.20251401.11,
author = {Bangoura Soriba and Camara Mohamed Lamine Tégui and Traore Aly and Diallo Amadou Yaya and Kaba Fatoumata and Barry Kadiatou Mamadou Bobo and Kaba Mohamed Lamine and Bah Alpha Oumar},
title = {Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea)},
journal = {Science Journal of Clinical Medicine},
volume = {14},
number = {1},
pages = {1-5},
doi = {10.11648/j.sjcm.20251401.11},
url = {https://doi.org/10.11648/j.sjcm.20251401.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20251401.11},
abstract = {Acute renal failure (ARF) is a major public health problem, with incidence in newborns and children ranging from 4.5 to 82%, and mortality from 19 to 83%. The aim was to determine the frequency of acute renal failure in children admitted to the pediatric ward of the Hospital National Ignace Deen. Patients and Method: This was a dynamic descriptive study covering the period from April 1er to September 30 2023; children under 16 years of age with a sudden rise in creatinine above 1.6 mg/dl were included in the study. Results: The incidence of acute renal failure was 7.93%; mean age 8.04 ±3 years. The sex ratio was 2 in favor of men. Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor (91.67%, 66.67%, 58.33% and 56.25% respectively); proteinuria, hematuria and biluribinuria were found at Urine Test Strip (BU) (54.17%, 29.17% and 41.67% respectively). Stage I ARF predominated, at 52.02%; organic ARF was found in 54.10% of cases. Mortality in this series was 14.58%. Conclusion: the management of pediatric renal failure at the complication stage is currently a major problem for healthcare professionals, due to the lack of nephropediatric services or specialized centers for extra-renal purification in the various health facilities in Guinea.},
year = {2025}
}
TY - JOUR
T1 - Epidemiological and Clinical Aspects of Arf in the Pediatrics Department of the Ignace Denn National Hospital in Conakry (Guinea)
AU - Bangoura Soriba
AU - Camara Mohamed Lamine Tégui
AU - Traore Aly
AU - Diallo Amadou Yaya
AU - Kaba Fatoumata
AU - Barry Kadiatou Mamadou Bobo
AU - Kaba Mohamed Lamine
AU - Bah Alpha Oumar
Y1 - 2025/01/17
PY - 2025
N1 - https://doi.org/10.11648/j.sjcm.20251401.11
DO - 10.11648/j.sjcm.20251401.11
T2 - Science Journal of Clinical Medicine
JF - Science Journal of Clinical Medicine
JO - Science Journal of Clinical Medicine
SP - 1
EP - 5
PB - Science Publishing Group
SN - 2327-2732
UR - https://doi.org/10.11648/j.sjcm.20251401.11
AB - Acute renal failure (ARF) is a major public health problem, with incidence in newborns and children ranging from 4.5 to 82%, and mortality from 19 to 83%. The aim was to determine the frequency of acute renal failure in children admitted to the pediatric ward of the Hospital National Ignace Deen. Patients and Method: This was a dynamic descriptive study covering the period from April 1er to September 30 2023; children under 16 years of age with a sudden rise in creatinine above 1.6 mg/dl were included in the study. Results: The incidence of acute renal failure was 7.93%; mean age 8.04 ±3 years. The sex ratio was 2 in favor of men. Clinical signs were dominated by fever, physical asthenia, anorexia and conjunctival pallor (91.67%, 66.67%, 58.33% and 56.25% respectively); proteinuria, hematuria and biluribinuria were found at Urine Test Strip (BU) (54.17%, 29.17% and 41.67% respectively). Stage I ARF predominated, at 52.02%; organic ARF was found in 54.10% of cases. Mortality in this series was 14.58%. Conclusion: the management of pediatric renal failure at the complication stage is currently a major problem for healthcare professionals, due to the lack of nephropediatric services or specialized centers for extra-renal purification in the various health facilities in Guinea.
VL - 14
IS - 1
ER -
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