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Epilepsy and Depression, Comorbidity Problems of Treatment Tactics

Received: 14 August 2020     Accepted: 24 August 2020     Published: 21 September 2020
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Abstract

Objective: Despite the availability of literary data on the treatment of comorbidity of epilepsy and depression, their therapy has not been fully resolved. However, epilepsy and depression are often combined. Materials and Methods: The aim of the study was development therapy in the comorbidity of epilepsy and depression in adults. The study included 100 patients with epilepsy. The severity of depression was studied by using the Hamilton scale, ICD-10 and DSM-5 criterions. Patients were observed at the Mental Health Center of the Ministry of Health of the Republic of Azerbaijan from January 2018 to January 2020 for 24 months. Patients took standard antiepileptic drugs (depakin-chrono 1000 mg/day, lamotrigine 150 mg/day, levitracetam 3000 mg/day) and antidepressant drug-citalopram was taken 10 mg twice a day, in the morning and in the evening. Results: Depression of varying severity was detected in 70 % of the examined patients 10 cases of mild, 40 moderate and 20 case of severe depression without psychotic symptoms. Conclusion: The combination of anticonvulsants with antidepressants Citalopram 10 mg in morning and evening (per os) reduces the frequency of seizures and reduces the severity of depression. The study of comorbidity of epilepsy and depression is of great theoretical and practical importance. First, it will contribute to the early detection of depression. Second, prevent suicides. Third, it will help reduce refractory epilepsy. Finally, improve their quality of life for patients with epilepsy.

Published in Rehabilitation Science (Volume 5, Issue 3)
DOI 10.11648/j.rs.20200503.11
Page(s) 18-23
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Epilepsy, Depression, Comorbidity, Treatment

References
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Cite This Article
  • APA Style

    Nadir Aliyev, Zafar Aliyev. (2020). Epilepsy and Depression, Comorbidity Problems of Treatment Tactics. Rehabilitation Science, 5(3), 18-23. https://doi.org/10.11648/j.rs.20200503.11

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    ACS Style

    Nadir Aliyev; Zafar Aliyev. Epilepsy and Depression, Comorbidity Problems of Treatment Tactics. Rehabil. Sci. 2020, 5(3), 18-23. doi: 10.11648/j.rs.20200503.11

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    AMA Style

    Nadir Aliyev, Zafar Aliyev. Epilepsy and Depression, Comorbidity Problems of Treatment Tactics. Rehabil Sci. 2020;5(3):18-23. doi: 10.11648/j.rs.20200503.11

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  • @article{10.11648/j.rs.20200503.11,
      author = {Nadir Aliyev and Zafar Aliyev},
      title = {Epilepsy and Depression, Comorbidity Problems of Treatment Tactics},
      journal = {Rehabilitation Science},
      volume = {5},
      number = {3},
      pages = {18-23},
      doi = {10.11648/j.rs.20200503.11},
      url = {https://doi.org/10.11648/j.rs.20200503.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.rs.20200503.11},
      abstract = {Objective: Despite the availability of literary data on the treatment of comorbidity of epilepsy and depression, their therapy has not been fully resolved. However, epilepsy and depression are often combined. Materials and Methods: The aim of the study was development therapy in the comorbidity of epilepsy and depression in adults. The study included 100 patients with epilepsy. The severity of depression was studied by using the Hamilton scale, ICD-10 and DSM-5 criterions. Patients were observed at the Mental Health Center of the Ministry of Health of the Republic of Azerbaijan from January 2018 to January 2020 for 24 months. Patients took standard antiepileptic drugs (depakin-chrono 1000 mg/day, lamotrigine 150 mg/day, levitracetam 3000 mg/day) and antidepressant drug-citalopram was taken 10 mg twice a day, in the morning and in the evening. Results: Depression of varying severity was detected in 70 % of the examined patients 10 cases of mild, 40 moderate and 20 case of severe depression without psychotic symptoms. Conclusion: The combination of anticonvulsants with antidepressants Citalopram 10 mg in morning and evening (per os) reduces the frequency of seizures and reduces the severity of depression. The study of comorbidity of epilepsy and depression is of great theoretical and practical importance. First, it will contribute to the early detection of depression. Second, prevent suicides. Third, it will help reduce refractory epilepsy. Finally, improve their quality of life for patients with epilepsy.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Epilepsy and Depression, Comorbidity Problems of Treatment Tactics
    AU  - Nadir Aliyev
    AU  - Zafar Aliyev
    Y1  - 2020/09/21
    PY  - 2020
    N1  - https://doi.org/10.11648/j.rs.20200503.11
    DO  - 10.11648/j.rs.20200503.11
    T2  - Rehabilitation Science
    JF  - Rehabilitation Science
    JO  - Rehabilitation Science
    SP  - 18
    EP  - 23
    PB  - Science Publishing Group
    SN  - 2637-594X
    UR  - https://doi.org/10.11648/j.rs.20200503.11
    AB  - Objective: Despite the availability of literary data on the treatment of comorbidity of epilepsy and depression, their therapy has not been fully resolved. However, epilepsy and depression are often combined. Materials and Methods: The aim of the study was development therapy in the comorbidity of epilepsy and depression in adults. The study included 100 patients with epilepsy. The severity of depression was studied by using the Hamilton scale, ICD-10 and DSM-5 criterions. Patients were observed at the Mental Health Center of the Ministry of Health of the Republic of Azerbaijan from January 2018 to January 2020 for 24 months. Patients took standard antiepileptic drugs (depakin-chrono 1000 mg/day, lamotrigine 150 mg/day, levitracetam 3000 mg/day) and antidepressant drug-citalopram was taken 10 mg twice a day, in the morning and in the evening. Results: Depression of varying severity was detected in 70 % of the examined patients 10 cases of mild, 40 moderate and 20 case of severe depression without psychotic symptoms. Conclusion: The combination of anticonvulsants with antidepressants Citalopram 10 mg in morning and evening (per os) reduces the frequency of seizures and reduces the severity of depression. The study of comorbidity of epilepsy and depression is of great theoretical and practical importance. First, it will contribute to the early detection of depression. Second, prevent suicides. Third, it will help reduce refractory epilepsy. Finally, improve their quality of life for patients with epilepsy.
    VL  - 5
    IS  - 3
    ER  - 

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Author Information
  • Department of Psychiatry and Drug Addiction, Azerbaijan State Advanced Training Institute for Doctors Named by A. Aliyev, Baku, Azerbaijan Republic

  • Departments of Psychiatry, Azerbaijan Medical State University, Baku City, Azerbaijan Republic

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