| Peer-Reviewed

Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example

Received: 29 November 2020     Accepted: 15 December 2020     Published: 25 December 2020
Views:       Downloads:
Abstract

Objective to evaluate the rationality of naloxone injection superdrug specification by evidence-based medicine and adding modified Jadad scale, and to establish the evaluation standard of rational drug use. Methods 540 medical records of naloxone used in 2019 were extracted, and the use of naloxone was analyzed. At the same time, the evidence-based medical evidence used in naloxone superscript was collected and the literature was graded by improved Jadad scale.≥4 points were used as high quality literature. Combined with evidence-based medicine and improved Jadad scale, 540 medical records with naloxone were reviewed. Results In evidence-based medical evidence collection, the guidelines for clinical treatment of craniocerebral trauma clearly put forward that naloxone injection in craniocerebral injury has a clear indication, but also given a clear dosage and course of treatment. By using the modified Jadad scale to screen and score the literature after 2013, it is determined that the coma caused by cerebral infarction is also a reasonable indication of overstatement. Combined with evidence-based medicine and improved Jadad scale method, 87.3% of the indications for the use of naloxone injection in our hospital were within the range of rational use, and the evaluation standard of rational use of naloxone was established. Conclusion: It is a new attempt to provide evidence-based basis for over-explanatory drug use through evidence-based medicine and improved Jadad scale method.

Published in Pharmaceutical Science and Technology (Volume 4, Issue 2)
DOI 10.11648/j.pst.20200402.13
Page(s) 40-44
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Evidence-based Medicine, Modified Jadad Scale Method, Naloxone Injection, Superscript, Rational Application

References
[1] Decree No. 53 of the Ministry of Health of the People's Republic of China on prescription management [J]. Bulletin of the Ministry of Health of the People's Republic of China, 2007 (04): 1-10.
[2] Ministry of Health. Hospital prescription evaluation management standard: trial S]. Health management (2010) 28. 2010-02-10.
[3] Drug risk management group of the professional committee of therapeutic drug monitoring and research of the Chinese Pharmacology Society. Expert consensus on over-the-book drug use Journal of Adverse Drug Reaction, 2015, 17 (2): 101-103.
[4] Evidence-based evaluation of drug over-the-counter use (2015 edition) [J]. Published Drug Evaluation 12 (10): 33.
[5] Liu Hongyi, Jin Runlin, Shi Haoqiang. Study on the Jadad of 5-fluorouracil Injection in Ophthalmology of Hospital [J]. By Scale Chinese Medical Journal, 2020, 55 (6): 636-638.
[6] Jiang Jiyao, Zhu Cheng, Luo Zhong, et al. Guidelines for clinical treatment of craniocerebral trauma: M]. Shanghai: second military Medical University. 2015, 161.
[7] Huang Quanqing. A randomized parallel controlled study of Tongxinluo capsule and acupuncture combined with naloxone in the treatment of acute cerebral infarction [J]. 5 Journal of practical Chinese Medicine 32 (09): 38-41.
[8] Gao Lichen, Jia Hongyan. Effect of naloxone on treatment of senile patients with ischemic cerebral infarction [J]. And Chinese and Foreign Medical Research 15 (24): 13-14.
[9] Xu Chao, Li Bourne, Li Fang, Xing Mingyao, Zhu Hui, Shen Tao. The evaluation of therapeutic value of two different doses of naloxone in patients with severe craniocerebral injury using bispectral index [J].] by bispectral index Journal of Bengbu Medical College 41 (8): 1009-1011.
[10] Li is pleased. Clinical Analysis of Naloxone Treatment in Patients with Acute Cerebral Infarction [J]. Electronic Journal of Cardiovascular Diseases with Integrated Chinese and Western Medicine 4 (22): 36-37.
[11] Qian Jun. Effect of naloxone on senile multi-infarct dementia [J] and Contemporary Chinese Medicine, 2014, 21 (24): 101-102.
[12] Zuo Yongliang, Lei Zhaobao. Analysis of literature on 27 cases of adverse reactions of naloxone [J]. in the report Journal of Drug Epidemiology 20 (02): 106-108.
[13] Zhang Daejeon. An adverse reaction induced by morphine hydrochloride injection and naloxone hydrochloride injection after mixed hemorrhoids operation [J]. Chinese Journal of anorectal Diseases, 2019, 39 (01): 79.
[14] Ding Yuwei, Zeng Shiquan, Yang Haojiang, Xu Jinling. Analysis of 1 case of adverse reaction to facial edema caused by intravenous drip of naloxone [J]. in patients Anti-infective Pharmacy 14 (02): 356-357.
[15] Wu Yongpei, Yan Qing. Interpretation of Management Practices of Hospital Prescription Comment (Trial) and Evaluation of Clinical Use of Drugs. [J] Chinese Pharmacy. 2020, 21 (38): 3553-3557.
[16] Zhang Wen, Wang Lin, Zhao Yongli, et al. Evaluation of the use of evidence-based medicine for the use of alprostadil injection instructions [J]. and Chinese Journal of Hospital Pharmacy 37 (2): 177-180.
[17] Qiu Xiaochun. Meta Analysis of the Application of Bibliometrics in Medical Research [J]. Journal of Postgraduate Medical Sciences, 2014, 27 (7): 733-736.
[18] Instructions for the injection of naloxone hydrochloride Version 2019. Chengdu Tiantai Mountain Pharmaceutical Co., Ltd.
[19] Hong K Kim, Lewis S Nelson. Reducing the harm of opioid overdose with the safe use of naloxone: a pharmacologic review. 2015, 14 (7): 1137-1146.
Cite This Article
  • APA Style

    Zou Qingmei. (2020). Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example. Pharmaceutical Science and Technology, 4(2), 40-44. https://doi.org/10.11648/j.pst.20200402.13

    Copy | Download

    ACS Style

    Zou Qingmei. Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example. Pharm. Sci. Technol. 2020, 4(2), 40-44. doi: 10.11648/j.pst.20200402.13

    Copy | Download

    AMA Style

    Zou Qingmei. Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example. Pharm Sci Technol. 2020;4(2):40-44. doi: 10.11648/j.pst.20200402.13

    Copy | Download

  • @article{10.11648/j.pst.20200402.13,
      author = {Zou Qingmei},
      title = {Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example},
      journal = {Pharmaceutical Science and Technology},
      volume = {4},
      number = {2},
      pages = {40-44},
      doi = {10.11648/j.pst.20200402.13},
      url = {https://doi.org/10.11648/j.pst.20200402.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.pst.20200402.13},
      abstract = {Objective to evaluate the rationality of naloxone injection superdrug specification by evidence-based medicine and adding modified Jadad scale, and to establish the evaluation standard of rational drug use. Methods 540 medical records of naloxone used in 2019 were extracted, and the use of naloxone was analyzed. At the same time, the evidence-based medical evidence used in naloxone superscript was collected and the literature was graded by improved Jadad scale.≥4 points were used as high quality literature. Combined with evidence-based medicine and improved Jadad scale, 540 medical records with naloxone were reviewed. Results In evidence-based medical evidence collection, the guidelines for clinical treatment of craniocerebral trauma clearly put forward that naloxone injection in craniocerebral injury has a clear indication, but also given a clear dosage and course of treatment. By using the modified Jadad scale to screen and score the literature after 2013, it is determined that the coma caused by cerebral infarction is also a reasonable indication of overstatement. Combined with evidence-based medicine and improved Jadad scale method, 87.3% of the indications for the use of naloxone injection in our hospital were within the range of rational use, and the evaluation standard of rational use of naloxone was established. Conclusion: It is a new attempt to provide evidence-based basis for over-explanatory drug use through evidence-based medicine and improved Jadad scale method.},
     year = {2020}
    }
    

    Copy | Download

  • TY  - JOUR
    T1  - Addition of Modified Jadad Method to Evaluate the Rationality of Over-explanatory Drug Use: Taking Naloxone as an Example
    AU  - Zou Qingmei
    Y1  - 2020/12/25
    PY  - 2020
    N1  - https://doi.org/10.11648/j.pst.20200402.13
    DO  - 10.11648/j.pst.20200402.13
    T2  - Pharmaceutical Science and Technology
    JF  - Pharmaceutical Science and Technology
    JO  - Pharmaceutical Science and Technology
    SP  - 40
    EP  - 44
    PB  - Science Publishing Group
    SN  - 2640-4540
    UR  - https://doi.org/10.11648/j.pst.20200402.13
    AB  - Objective to evaluate the rationality of naloxone injection superdrug specification by evidence-based medicine and adding modified Jadad scale, and to establish the evaluation standard of rational drug use. Methods 540 medical records of naloxone used in 2019 were extracted, and the use of naloxone was analyzed. At the same time, the evidence-based medical evidence used in naloxone superscript was collected and the literature was graded by improved Jadad scale.≥4 points were used as high quality literature. Combined with evidence-based medicine and improved Jadad scale, 540 medical records with naloxone were reviewed. Results In evidence-based medical evidence collection, the guidelines for clinical treatment of craniocerebral trauma clearly put forward that naloxone injection in craniocerebral injury has a clear indication, but also given a clear dosage and course of treatment. By using the modified Jadad scale to screen and score the literature after 2013, it is determined that the coma caused by cerebral infarction is also a reasonable indication of overstatement. Combined with evidence-based medicine and improved Jadad scale method, 87.3% of the indications for the use of naloxone injection in our hospital were within the range of rational use, and the evaluation standard of rational use of naloxone was established. Conclusion: It is a new attempt to provide evidence-based basis for over-explanatory drug use through evidence-based medicine and improved Jadad scale method.
    VL  - 4
    IS  - 2
    ER  - 

    Copy | Download

Author Information
  • Department of Pharmacy, Sichuan Chongzhou People's Hospital, Chengdu, China

  • Sections