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The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection

Received: 4 November 2020     Accepted: 16 November 2020     Published: 9 July 2021
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Abstract

Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.

Published in Pathology and Laboratory Medicine (Volume 5, Issue 2)
DOI 10.11648/j.plm.20210502.11
Page(s) 19-25
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Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection

References
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[19] Zriba, S., Garcia-Gonzalez, D. G., Khalaf, O. H., Wheeler, L., Chaki, S. P., Rice-Ficht, A., Ficht, T. A. and Arenas-Gamboa, A. M., 2019. Vaccine safety studies of Brucella abortus S19 and S19ΔvjbR in pregnant swine. Vaccine: X, 3, p. 100041.
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  • APA Style

    Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. (2021). The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathology and Laboratory Medicine, 5(2), 19-25. https://doi.org/10.11648/j.plm.20210502.11

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    ACS Style

    Hiba Orsud; Ahmed Elmontaser Omer Mergani; Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol. Lab. Med. 2021, 5(2), 19-25. doi: 10.11648/j.plm.20210502.11

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    AMA Style

    Hiba Orsud, Ahmed Elmontaser Omer Mergani, Suliman Elsanousi. The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection. Pathol Lab Med. 2021;5(2):19-25. doi: 10.11648/j.plm.20210502.11

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  • @article{10.11648/j.plm.20210502.11,
      author = {Hiba Orsud and Ahmed Elmontaser Omer Mergani and Suliman Elsanousi},
      title = {The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection},
      journal = {Pathology and Laboratory Medicine},
      volume = {5},
      number = {2},
      pages = {19-25},
      doi = {10.11648/j.plm.20210502.11},
      url = {https://doi.org/10.11648/j.plm.20210502.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.plm.20210502.11},
      abstract = {Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.},
     year = {2021}
    }
    

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    T1  - The Correlation Between Helicobacter pylori SeroPositive Patients and Throat Infection
    AU  - Hiba Orsud
    AU  - Ahmed Elmontaser Omer Mergani
    AU  - Suliman Elsanousi
    Y1  - 2021/07/09
    PY  - 2021
    N1  - https://doi.org/10.11648/j.plm.20210502.11
    DO  - 10.11648/j.plm.20210502.11
    T2  - Pathology and Laboratory Medicine
    JF  - Pathology and Laboratory Medicine
    JO  - Pathology and Laboratory Medicine
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    PB  - Science Publishing Group
    SN  - 2640-4478
    UR  - https://doi.org/10.11648/j.plm.20210502.11
    AB  - Heliocobacter pylori besides being the cause of chronic gastritis it was shown be implicated in various extra gastric manifestation. Gastric juice infected with H. pylori might have important role in upper respiratory tract. However it has not been elucidated. Therefore this study aim to clarify whether H. pylori play a role in the etiology and pathogenesis of throat infection. 307 volunteers were participated in this study. Throat swabs from tonsils and oropharynx were collected, conventional bacteriological methods were applied for identification of pathogenic bacteria, followed by PCR confirmation. Along with, serum sample were collected for determination of anti-H. pylori IgG titer by quantitative ELISA method. Prior ICT antibody-based screening test were performed. Simultaneously questionnaire data form from our participants were collected for statistical analysis. This study was designed as case control study. From throat swabs Streptococcus pyogenes was the most common in our isolates. The mean of IgG antibody titer was 95.21 RU/ml, the positive samples for IgG was quite 88.2%. Clinical respiratory symptoms were observed only in 9.7% of participants in this study 89% of them confirmed with H. pylori. Statistical data showed very high significant correlation between pathogenic bacteria S. pyogenes and H. pylori infection.
    VL  - 5
    IS  - 2
    ER  - 

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Author Information
  • Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan

  • Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan

  • Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum, Khartoum North, Sudan

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