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Lipocryolysis: Cooling Speed Affects Adipocyte Survival

Received: 19 December 2014     Accepted: 23 December 2014     Published: 31 December 2014
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Abstract

New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds.

Published in Journal of Surgery (Volume 3, Issue 1-1)

This article belongs to the Special Issue Breakthroughs in Aesthetic Medicine

DOI 10.11648/j.js.s.2015030101.14
Page(s) 11-13
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Lipocryolysis, Cooling Speed, Adipocyte

References
[1] Pinto H, Arredondo E, Ricart-Jané D. Study for the Evaluation of Adipocytic Changes after a Simil-Lipocryolysis Stimulus. Cryoletters 34(1) (2013)100-5
[2] Pinto H, Pardina E, Ricart-Jané D. X-ray diffraction analysis confirms intra-adipocitary lipid crystallization after a lipocryolysis-like stimulus. Cryoletters 34(6) (2013) 619-23
[3] Pinto H, Pardina E, Ricart-Jané D. X-ray diffraction analysis confirms intra-adipocitary lipid crystallization after a lipocryolysis-like stimulus. Cryoletters 34(6) (2013) 619-23
[4] Coleman S, Sachdeva K, Egbert B, Preciado JA, Allison J. Clinical efficacy of non-invasive Cryolipolysis™ and its effects on peripheral nerves AesthPlast Surg 33(2009) 482–8
[5] Pinto H, García-Cruz E, Melamed G. Study to Evaluate the Action of Lipocryolysis. Cryoletters 33(3) (2013):176-80
[6] Manstein D, Laubach H, Watannabe K, Farinelli W, ZurakowskiD, Anderson RR. Selective cryolysis: a novel method of non-invasive fat reduction. Las in Surg and Med 40(2008)595-604
[7] Zelickson B, Egbert B, Preciado JA, Allison J, Springer K, Manstein D. Cryolipolysis™ for noninvasive fat cell destruction: initial results from a pig model. Dermatol Surg 35(10) (2009) 1462–70
Cite This Article
  • APA Style

    Hernán Pinto, David Ricart-Jané, Eva Pardina, Graciela Melamed. (2014). Lipocryolysis: Cooling Speed Affects Adipocyte Survival. Journal of Surgery, 3(1-1), 11-13. https://doi.org/10.11648/j.js.s.2015030101.14

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    ACS Style

    Hernán Pinto; David Ricart-Jané; Eva Pardina; Graciela Melamed. Lipocryolysis: Cooling Speed Affects Adipocyte Survival. J. Surg. 2014, 3(1-1), 11-13. doi: 10.11648/j.js.s.2015030101.14

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    AMA Style

    Hernán Pinto, David Ricart-Jané, Eva Pardina, Graciela Melamed. Lipocryolysis: Cooling Speed Affects Adipocyte Survival. J Surg. 2014;3(1-1):11-13. doi: 10.11648/j.js.s.2015030101.14

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  • @article{10.11648/j.js.s.2015030101.14,
      author = {Hernán Pinto and David Ricart-Jané and Eva Pardina and Graciela Melamed},
      title = {Lipocryolysis: Cooling Speed Affects Adipocyte Survival},
      journal = {Journal of Surgery},
      volume = {3},
      number = {1-1},
      pages = {11-13},
      doi = {10.11648/j.js.s.2015030101.14},
      url = {https://doi.org/10.11648/j.js.s.2015030101.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.s.2015030101.14},
      abstract = {New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds.},
     year = {2014}
    }
    

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  • TY  - JOUR
    T1  - Lipocryolysis: Cooling Speed Affects Adipocyte Survival
    AU  - Hernán Pinto
    AU  - David Ricart-Jané
    AU  - Eva Pardina
    AU  - Graciela Melamed
    Y1  - 2014/12/31
    PY  - 2014
    N1  - https://doi.org/10.11648/j.js.s.2015030101.14
    DO  - 10.11648/j.js.s.2015030101.14
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 11
    EP  - 13
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.s.2015030101.14
    AB  - New knowledge about crystallization has surfaced recently, since some of the last lipocryolysis publications have focused on how it works [4, 5]. However, although its action is better understood day after day, there is a sense of feeling that its clinical outcome could be improved. Kinetic particularities of crystal formation process allowed us to think that the cooling speed might be determinant in the results achieved in a lipocryolysis session. Adipocytes from six male rats where isolated and then exposed to 1ºC/min, 2ºC/min and 6ºC/min cooling speeds until they reached 8ºC and were kept at that temperature for 30 minutes. Cell damage was significantly higher in 1ºC/min cooling speed than in other cooling speeds.
    VL  - 3
    IS  - 1-1
    ER  - 

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Author Information
  • Aesthetic Specialties and Aging Research Institute (i2e3), Barcelona, Spain

  • Metabolism Research Center (CEREMET), Barcelona, Spain

  • Metabolism Research Center (CEREMET), Barcelona, Spain

  • University Maimonides, Buenos Aires, Argentina

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