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Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review

Received: 23 August 2021     Accepted: 22 September 2021     Published: 30 October 2021
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Abstract

Background: Malignant peritoneal mesothelioma (PeM) is a rare form of malignant mesothelioma that accounts for 10-15% of all cases of mesothelioma. Of these rare tumors, the rhabdoid subtype is exceptionally infrequent with only three cases reported in the current literature. PeM most commonly presents with non-specific symptoms such as abdominal distention, anorexia and weight loss that are difficult to diagnose until the disease is advanced. In this case report, we present a case of malignant peritoneal rhabdoid mesothelioma and review the literature. Case presentation: The patient is a 76-year-old woman who originally presented with necrotizing pancreatitis one year prior to diagnosis. The patient continued to complain of abdominal pain, nausea, vomiting, and weight loss. She experienced recurrent deep vein thrombosis (DVT), recurrent chylous, and mucinous ascites. Diagnostic work-up including MRI, repeat CT, EUS, and MRCP were inconclusive. Additionally, cytology from multiple paracenteses were negative for malignancy. Diagnostic laparoscopy revealed diffuse carcinomatosis, abdominal wall and peritoneal implants and a large epigastric mass. Biopsies of lesions taken during the procedure were identified as peritoneal mesothelioma. Conclusions: To our knowledge, we have presented the first case of PeM with rhabdoid features present in the peritoneum and in gastric polyps. The large amount of histopathogical variation of these tumors requires surgical biopsy, as cytology alone is non-diagnostic.

Published in Journal of Surgery (Volume 9, Issue 5)
DOI 10.11648/j.js.20210905.16
Page(s) 246-251
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Malignant Peritoneal Mesothelioma (PeM), Malignant Mesothelioma (MM), Rhabdoid Mesothelioma

References
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  • APA Style

    Dorcie Gillette, Jennifer Perone, Anna Rotkiewicz, Rawan Dayah, Jing He, et al. (2021). Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review. Journal of Surgery, 9(5), 246-251. https://doi.org/10.11648/j.js.20210905.16

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    ACS Style

    Dorcie Gillette; Jennifer Perone; Anna Rotkiewicz; Rawan Dayah; Jing He, et al. Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review. J. Surg. 2021, 9(5), 246-251. doi: 10.11648/j.js.20210905.16

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    AMA Style

    Dorcie Gillette, Jennifer Perone, Anna Rotkiewicz, Rawan Dayah, Jing He, et al. Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review. J Surg. 2021;9(5):246-251. doi: 10.11648/j.js.20210905.16

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  • @article{10.11648/j.js.20210905.16,
      author = {Dorcie Gillette and Jennifer Perone and Anna Rotkiewicz and Rawan Dayah and Jing He and Douglas Tyler and John Patrick Walker},
      title = {Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review},
      journal = {Journal of Surgery},
      volume = {9},
      number = {5},
      pages = {246-251},
      doi = {10.11648/j.js.20210905.16},
      url = {https://doi.org/10.11648/j.js.20210905.16},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20210905.16},
      abstract = {Background: Malignant peritoneal mesothelioma (PeM) is a rare form of malignant mesothelioma that accounts for 10-15% of all cases of mesothelioma. Of these rare tumors, the rhabdoid subtype is exceptionally infrequent with only three cases reported in the current literature. PeM most commonly presents with non-specific symptoms such as abdominal distention, anorexia and weight loss that are difficult to diagnose until the disease is advanced. In this case report, we present a case of malignant peritoneal rhabdoid mesothelioma and review the literature. Case presentation: The patient is a 76-year-old woman who originally presented with necrotizing pancreatitis one year prior to diagnosis. The patient continued to complain of abdominal pain, nausea, vomiting, and weight loss. She experienced recurrent deep vein thrombosis (DVT), recurrent chylous, and mucinous ascites. Diagnostic work-up including MRI, repeat CT, EUS, and MRCP were inconclusive. Additionally, cytology from multiple paracenteses were negative for malignancy. Diagnostic laparoscopy revealed diffuse carcinomatosis, abdominal wall and peritoneal implants and a large epigastric mass. Biopsies of lesions taken during the procedure were identified as peritoneal mesothelioma. Conclusions: To our knowledge, we have presented the first case of PeM with rhabdoid features present in the peritoneum and in gastric polyps. The large amount of histopathogical variation of these tumors requires surgical biopsy, as cytology alone is non-diagnostic.},
     year = {2021}
    }
    

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    T1  - Malignant Peritoneal Mesothelioma with Rhabdoid Features Masquerading as Idiopathic Necrotizing Pancreatitis with Mucinous Ascites: A Case Report and Literature Review
    AU  - Dorcie Gillette
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    AB  - Background: Malignant peritoneal mesothelioma (PeM) is a rare form of malignant mesothelioma that accounts for 10-15% of all cases of mesothelioma. Of these rare tumors, the rhabdoid subtype is exceptionally infrequent with only three cases reported in the current literature. PeM most commonly presents with non-specific symptoms such as abdominal distention, anorexia and weight loss that are difficult to diagnose until the disease is advanced. In this case report, we present a case of malignant peritoneal rhabdoid mesothelioma and review the literature. Case presentation: The patient is a 76-year-old woman who originally presented with necrotizing pancreatitis one year prior to diagnosis. The patient continued to complain of abdominal pain, nausea, vomiting, and weight loss. She experienced recurrent deep vein thrombosis (DVT), recurrent chylous, and mucinous ascites. Diagnostic work-up including MRI, repeat CT, EUS, and MRCP were inconclusive. Additionally, cytology from multiple paracenteses were negative for malignancy. Diagnostic laparoscopy revealed diffuse carcinomatosis, abdominal wall and peritoneal implants and a large epigastric mass. Biopsies of lesions taken during the procedure were identified as peritoneal mesothelioma. Conclusions: To our knowledge, we have presented the first case of PeM with rhabdoid features present in the peritoneum and in gastric polyps. The large amount of histopathogical variation of these tumors requires surgical biopsy, as cytology alone is non-diagnostic.
    VL  - 9
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Author Information
  • School of Medicine, University of Texas Medical Branch, Galveston, USA

  • Department of Surgery, University of Texas Medical Branch, Galveston, USA

  • Department of Internal Medicine, University of Texas Medical Branch, Galveston, USA

  • Department of Internal Medicine, University of Texas Medical Branch, Galveston, USA

  • Department of Pathology, University of Texas Medical Branch, Galveston, USA

  • Department of Surgery, University of Texas Medical Branch, Galveston, USA

  • Department of Surgery, University of Texas Medical Branch, Galveston, USA

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