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Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature

Received: 18 February 2019     Accepted: 9 April 2019     Published: 6 May 2019
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Abstract

Fibroadenoma (FAD) is the most common type of breast lesion especially in young female individuals. Although malignant transformation in FAD is rare, several reports have described a higher risk of subsequent breast carcinoma amongst patients who have FAD with specific histologic features. The case of a 30-year-old female exhibiting invasive lobular carcinoma arising within an excised fibroadenoma is being presented. The literature was reviewed with regards to the increased likelihood of developing breast cancer in patients with FADs. The incidence of cancer found in an excised FAD is extremely low, but there are specific proliferative changes on the histology after a core needle biopsy, that they should warrant excision biopsy.

Published in Journal of Surgery (Volume 7, Issue 2)
DOI 10.11648/j.js.20190702.12
Page(s) 35-37
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Fibroadenoma, Invasive Lobular Cancer, Core Biopsy, Excision Biopsy

References
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[16] Fukuda M, Nagao K, Nishimuta R, Matsuda M, Baba K, Ueno Y, Morinaga H, Omachi H, Hamada T: Carcinoma arising in fibroadenoma of the breast- a case report and review of the literature. Jpn J Surg 1989; 19:593-596.
[17] Aziza Nassar, Daniel W., Visscher, Amy C. Degnim, Messr. Ryan D. Frank, Messr. Robert A. Vierkant, Marlene Frost, Derek C. Radisky, Celine Vachon, Ruth A. Kraft, Lynn C. Hartmann, Karthik Ghosh. Complex Fibroadenoma and Breast Cancer Risk: Mayo Clinic Benign Breast Disease Cohort Study. Breast Cancer Res Treat 2015; 153(2): 397-405.
[18] Neville G, Neill CO, Murphy R, Corrigan M, Redmond PH, Feeley L, Bennett MW, O'Connell F, Browne TJ. Is excision biopsy of fibroadenomas based solely on size criteria warranted? Breast J 2018 May; 25. doi: 10.1111/tbj.13069.
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Cite This Article
  • APA Style

    Dimitrios Kokkonis, Mohamed Razick Sait, Anne Thorpe, Ralia Bunza, Rajiv Vashisht, et al. (2019). Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature. Journal of Surgery, 7(2), 35-37. https://doi.org/10.11648/j.js.20190702.12

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    ACS Style

    Dimitrios Kokkonis; Mohamed Razick Sait; Anne Thorpe; Ralia Bunza; Rajiv Vashisht, et al. Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature. J. Surg. 2019, 7(2), 35-37. doi: 10.11648/j.js.20190702.12

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    AMA Style

    Dimitrios Kokkonis, Mohamed Razick Sait, Anne Thorpe, Ralia Bunza, Rajiv Vashisht, et al. Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature. J Surg. 2019;7(2):35-37. doi: 10.11648/j.js.20190702.12

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  • @article{10.11648/j.js.20190702.12,
      author = {Dimitrios Kokkonis and Mohamed Razick Sait and Anne Thorpe and Ralia Bunza and Rajiv Vashisht and Musa Barkeji},
      title = {Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature},
      journal = {Journal of Surgery},
      volume = {7},
      number = {2},
      pages = {35-37},
      doi = {10.11648/j.js.20190702.12},
      url = {https://doi.org/10.11648/j.js.20190702.12},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.js.20190702.12},
      abstract = {Fibroadenoma (FAD) is the most common type of breast lesion especially in young female individuals. Although malignant transformation in FAD is rare, several reports have described a higher risk of subsequent breast carcinoma amongst patients who have FAD with specific histologic features. The case of a 30-year-old female exhibiting invasive lobular carcinoma arising within an excised fibroadenoma is being presented. The literature was reviewed with regards to the increased likelihood of developing breast cancer in patients with FADs. The incidence of cancer found in an excised FAD is extremely low, but there are specific proliferative changes on the histology after a core needle biopsy, that they should warrant excision biopsy.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Invasive Lobular Carcinoma within a Fibroadenoma: A Case Report and Review of the Literature
    AU  - Dimitrios Kokkonis
    AU  - Mohamed Razick Sait
    AU  - Anne Thorpe
    AU  - Ralia Bunza
    AU  - Rajiv Vashisht
    AU  - Musa Barkeji
    Y1  - 2019/05/06
    PY  - 2019
    N1  - https://doi.org/10.11648/j.js.20190702.12
    DO  - 10.11648/j.js.20190702.12
    T2  - Journal of Surgery
    JF  - Journal of Surgery
    JO  - Journal of Surgery
    SP  - 35
    EP  - 37
    PB  - Science Publishing Group
    SN  - 2330-0930
    UR  - https://doi.org/10.11648/j.js.20190702.12
    AB  - Fibroadenoma (FAD) is the most common type of breast lesion especially in young female individuals. Although malignant transformation in FAD is rare, several reports have described a higher risk of subsequent breast carcinoma amongst patients who have FAD with specific histologic features. The case of a 30-year-old female exhibiting invasive lobular carcinoma arising within an excised fibroadenoma is being presented. The literature was reviewed with regards to the increased likelihood of developing breast cancer in patients with FADs. The incidence of cancer found in an excised FAD is extremely low, but there are specific proliferative changes on the histology after a core needle biopsy, that they should warrant excision biopsy.
    VL  - 7
    IS  - 2
    ER  - 

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Author Information
  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdom

  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdom

  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdom

  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdomi

  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdom

  • Department of Breast Surgery, West Middlesex University Hospital, London, United Kingdom

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