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Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats

Received: 15 December 2014     Accepted: 16 December 2014     Published: 27 February 2015
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Abstract

We investigated the effects of somatostatin on the ileal movements after gravity stress and compared these effects between male and female rats. Using an in vitro preparation, measurements of ileal movements evoked by somatostatin application were done at 1, 3, 15 and 30 days after 3G gravity loading-conditioning. Mixed phasic and tonic patterns were observed in the ileal muscle activities. Gravity-stress decreased or antagonized somatostatin inhibitory effects on tonic ileal contraction at an early stage (at day 3) in females, but not in males, indicating that sex differences exist in the way that changes of somatostatin sensitivity is modulated by stress conditioning.

Published in Journal of Food and Nutrition Sciences (Volume 3, Issue 3-1)

This article belongs to the Special Issue Effects of Foods on Gastrointestinal, Metabolic and Immunological Function

DOI 10.11648/j.jfns.s.2015030301.11
Page(s) 1-4
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Somatostatin, Gravity Stress, Ileum, Sex Difference, Rat

References
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Cite This Article
  • APA Style

    Mari Kimoto, Jorge L. Zeredo, Masato S. Ota, Zenro Nihei, Kazuo Toda. (2015). Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats. Journal of Food and Nutrition Sciences, 3(3-1), 1-4. https://doi.org/10.11648/j.jfns.s.2015030301.11

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    ACS Style

    Mari Kimoto; Jorge L. Zeredo; Masato S. Ota; Zenro Nihei; Kazuo Toda. Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats. J. Food Nutr. Sci. 2015, 3(3-1), 1-4. doi: 10.11648/j.jfns.s.2015030301.11

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    AMA Style

    Mari Kimoto, Jorge L. Zeredo, Masato S. Ota, Zenro Nihei, Kazuo Toda. Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats. J Food Nutr Sci. 2015;3(3-1):1-4. doi: 10.11648/j.jfns.s.2015030301.11

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  • @article{10.11648/j.jfns.s.2015030301.11,
      author = {Mari Kimoto and Jorge L. Zeredo and Masato S. Ota and Zenro Nihei and Kazuo Toda},
      title = {Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats},
      journal = {Journal of Food and Nutrition Sciences},
      volume = {3},
      number = {3-1},
      pages = {1-4},
      doi = {10.11648/j.jfns.s.2015030301.11},
      url = {https://doi.org/10.11648/j.jfns.s.2015030301.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfns.s.2015030301.11},
      abstract = {We investigated the effects of somatostatin on the ileal movements after gravity stress and compared these effects between male and female rats. Using an in vitro preparation, measurements of ileal movements evoked by somatostatin application were done at 1, 3, 15 and 30 days after 3G gravity loading-conditioning. Mixed phasic and tonic patterns were observed in the ileal muscle activities. Gravity-stress decreased or antagonized somatostatin inhibitory effects on tonic ileal contraction at an early stage (at day 3) in females, but not in males, indicating that sex differences exist in the way that changes of somatostatin sensitivity is modulated by stress conditioning.},
     year = {2015}
    }
    

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  • TY  - JOUR
    T1  - Sex Differences in Ileal Somatostatin-Response after Stress Conditioning in Rats
    AU  - Mari Kimoto
    AU  - Jorge L. Zeredo
    AU  - Masato S. Ota
    AU  - Zenro Nihei
    AU  - Kazuo Toda
    Y1  - 2015/02/27
    PY  - 2015
    N1  - https://doi.org/10.11648/j.jfns.s.2015030301.11
    DO  - 10.11648/j.jfns.s.2015030301.11
    T2  - Journal of Food and Nutrition Sciences
    JF  - Journal of Food and Nutrition Sciences
    JO  - Journal of Food and Nutrition Sciences
    SP  - 1
    EP  - 4
    PB  - Science Publishing Group
    SN  - 2330-7293
    UR  - https://doi.org/10.11648/j.jfns.s.2015030301.11
    AB  - We investigated the effects of somatostatin on the ileal movements after gravity stress and compared these effects between male and female rats. Using an in vitro preparation, measurements of ileal movements evoked by somatostatin application were done at 1, 3, 15 and 30 days after 3G gravity loading-conditioning. Mixed phasic and tonic patterns were observed in the ileal muscle activities. Gravity-stress decreased or antagonized somatostatin inhibitory effects on tonic ileal contraction at an early stage (at day 3) in females, but not in males, indicating that sex differences exist in the way that changes of somatostatin sensitivity is modulated by stress conditioning.
    VL  - 3
    IS  - 3-1
    ER  - 

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Author Information
  • Physiological Laboratories, Japan Women's University, Tokyo, Japan

  • Graduate Program in Health Sciences and Technology, University of Brasilia, Brasilia, Brazil

  • Laboratory of Biochemistry and Food Biology, Japan Women's University, Tokyo, Japan

  • Integrative Sensory Physiology, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

  • Physiological Laboratories, Japan Women's University, Tokyo, Japan

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