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Macular Hole Following Retained Subfoveal PFCL

Received: 18 July 2021     Accepted: 3 August 2021     Published: 24 August 2021
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Abstract

Introduction: Perfluorocarbon liquids (PFCLs) were first developed in 1970s as possible substitutes to erythrocytes because of their capacity to dissolve relatively large amounts of oxygen. Based on their properties, PFCL are widely used in complex retinal detachments, but they can cause complications in cases of subretinal retention. Migration of peripherally located subretinal PFCL towards the fovea is well established, but spontaneous resolution of sub-foveal PFCL without surgical evacuation or displacement has rarely been described. Case report: We report a case of a 48 year old male on whom a vitrectomy was performed for a retinal detachment with scleral tear following trauma. PFCL was used for ten days as a temporary intraocular tamponade for retinal flattening. A second vitrectomy was done to replace the PFCL with silicone oil, following which retained sub-foveal PFCL was noted. Result: Fourteen months later, a macular hole developed and PFCL disappeared. Slight superior displacement of the macular area was observed due to contraction of fibrous proliferation superiorly. There was no decrease in visual acuity. Patient was advised to undergo silicon oil removal. CONCLUSION: In the future, improved understanding of the mechanisms of spontaneous resolution may enable the development of non-surgical methods to displace sub-foveal PFCL.

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 3)
DOI 10.11648/j.ijovs.20210603.14
Page(s) 172-175
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

PFCL, Sub Retinal, Macular Hole

References
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[2] Geyer RP. “Bloodless” rats through the use of artificial blood substitutes. Fed Proc. 1975; 34 (6): 1499-505.
[3] Chang S, Zimmerman NJ, Iwamoto T, et al. Experimental vitreous replacement with perfluorotributylamine. Am J Ophthalmol. 1987; 103 (1): 29-37.
[4] Chang S. Low viscosity liquid fluorochemicals in vitreous surgery. Am J Ophthalmol. 1987; 103 (1): 38-43.
[5] Velikay M, Wedrich A, Stolba U, et al. Experimental long-term vitreous replacement with purified and nonpurified perfluorodecalin. Am J Ophthalmol. 1993; 116 (5): 565-70.
[6] Ohji M. Perfluorocarbon Liquid: Handle with Care: A quick guide to avoiding retained subretinal PFCL and removing it when it occurs. Retina Today. March 2016: 26-27.
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[18] Tewari A, Eliott D, Singh CN, Garcia-Valenzuela E, Ito Y, Abrams GW. Changes in retinal sensitivity from retained subretinal perfluorocarbon liquid. Retina. 2009; 29 (2): 248–50.
[19] Mirshahi A, Ghasemi F, Zarei M, Karkhaneh R, Ahmadraji A, Polkinghorne PJ. Removal of subfoveal perfluorocarbon liquid: Report of 3 cases. J Curr Ophthalmol. 2017; 29 (4): 324-8.
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Cite This Article
  • APA Style

    Navneet Mehrotra, Gayathri Mohan, Manish Nagpal, Sham Talati, Akansha Sharma. (2021). Macular Hole Following Retained Subfoveal PFCL. International Journal of Ophthalmology & Visual Science, 6(3), 172-175. https://doi.org/10.11648/j.ijovs.20210603.14

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    ACS Style

    Navneet Mehrotra; Gayathri Mohan; Manish Nagpal; Sham Talati; Akansha Sharma. Macular Hole Following Retained Subfoveal PFCL. Int. J. Ophthalmol. Vis. Sci. 2021, 6(3), 172-175. doi: 10.11648/j.ijovs.20210603.14

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    AMA Style

    Navneet Mehrotra, Gayathri Mohan, Manish Nagpal, Sham Talati, Akansha Sharma. Macular Hole Following Retained Subfoveal PFCL. Int J Ophthalmol Vis Sci. 2021;6(3):172-175. doi: 10.11648/j.ijovs.20210603.14

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  • @article{10.11648/j.ijovs.20210603.14,
      author = {Navneet Mehrotra and Gayathri Mohan and Manish Nagpal and Sham Talati and Akansha Sharma},
      title = {Macular Hole Following Retained Subfoveal PFCL},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {6},
      number = {3},
      pages = {172-175},
      doi = {10.11648/j.ijovs.20210603.14},
      url = {https://doi.org/10.11648/j.ijovs.20210603.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210603.14},
      abstract = {Introduction: Perfluorocarbon liquids (PFCLs) were first developed in 1970s as possible substitutes to erythrocytes because of their capacity to dissolve relatively large amounts of oxygen. Based on their properties, PFCL are widely used in complex retinal detachments, but they can cause complications in cases of subretinal retention. Migration of peripherally located subretinal PFCL towards the fovea is well established, but spontaneous resolution of sub-foveal PFCL without surgical evacuation or displacement has rarely been described. Case report: We report a case of a 48 year old male on whom a vitrectomy was performed for a retinal detachment with scleral tear following trauma. PFCL was used for ten days as a temporary intraocular tamponade for retinal flattening. A second vitrectomy was done to replace the PFCL with silicone oil, following which retained sub-foveal PFCL was noted. Result: Fourteen months later, a macular hole developed and PFCL disappeared. Slight superior displacement of the macular area was observed due to contraction of fibrous proliferation superiorly. There was no decrease in visual acuity. Patient was advised to undergo silicon oil removal. CONCLUSION: In the future, improved understanding of the mechanisms of spontaneous resolution may enable the development of non-surgical methods to displace sub-foveal PFCL.},
     year = {2021}
    }
    

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  • TY  - JOUR
    T1  - Macular Hole Following Retained Subfoveal PFCL
    AU  - Navneet Mehrotra
    AU  - Gayathri Mohan
    AU  - Manish Nagpal
    AU  - Sham Talati
    AU  - Akansha Sharma
    Y1  - 2021/08/24
    PY  - 2021
    N1  - https://doi.org/10.11648/j.ijovs.20210603.14
    DO  - 10.11648/j.ijovs.20210603.14
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
    SP  - 172
    EP  - 175
    PB  - Science Publishing Group
    SN  - 2637-3858
    UR  - https://doi.org/10.11648/j.ijovs.20210603.14
    AB  - Introduction: Perfluorocarbon liquids (PFCLs) were first developed in 1970s as possible substitutes to erythrocytes because of their capacity to dissolve relatively large amounts of oxygen. Based on their properties, PFCL are widely used in complex retinal detachments, but they can cause complications in cases of subretinal retention. Migration of peripherally located subretinal PFCL towards the fovea is well established, but spontaneous resolution of sub-foveal PFCL without surgical evacuation or displacement has rarely been described. Case report: We report a case of a 48 year old male on whom a vitrectomy was performed for a retinal detachment with scleral tear following trauma. PFCL was used for ten days as a temporary intraocular tamponade for retinal flattening. A second vitrectomy was done to replace the PFCL with silicone oil, following which retained sub-foveal PFCL was noted. Result: Fourteen months later, a macular hole developed and PFCL disappeared. Slight superior displacement of the macular area was observed due to contraction of fibrous proliferation superiorly. There was no decrease in visual acuity. Patient was advised to undergo silicon oil removal. CONCLUSION: In the future, improved understanding of the mechanisms of spontaneous resolution may enable the development of non-surgical methods to displace sub-foveal PFCL.
    VL  - 6
    IS  - 3
    ER  - 

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Author Information
  • Department of Retina and Vitreous, Retina Foundation, Ahmedabad, India

  • Department of Retina and Vitreous, Retina Foundation, Ahmedabad, India

  • Department of Retina and Vitreous, Retina Foundation, Ahmedabad, India

  • Department of Retina and Vitreous, Retina Foundation, Ahmedabad, India

  • Department of Retina and Vitreous, Retina Foundation, Ahmedabad, India

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