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Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences

Received: 26 May 2021     Accepted: 8 June 2021     Published: 15 June 2021
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Abstract

The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p<0.05. DM1 patients with stage II severity bacterial keratitis were more prone for longer duration of the disease and worse consequences. Therefore, on day 24 in 33.3% diabetic patients with stage II severity bacterial keratitis corneal ulcer was not found to be healed. Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.

Published in International Journal of Ophthalmology & Visual Science (Volume 6, Issue 2)
DOI 10.11648/j.ijovs.20210602.19
Page(s) 115-121
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2021. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Bacterial Keratitis, Course of Bacterial Keratitis Course, Consequences of Bacterial Keratitis

References
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  • APA Style

    Olesia Zavoloka, Pavlo Bezditko. (2021). Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. International Journal of Ophthalmology & Visual Science, 6(2), 115-121. https://doi.org/10.11648/j.ijovs.20210602.19

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    ACS Style

    Olesia Zavoloka; Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int. J. Ophthalmol. Vis. Sci. 2021, 6(2), 115-121. doi: 10.11648/j.ijovs.20210602.19

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    AMA Style

    Olesia Zavoloka, Pavlo Bezditko. Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences. Int J Ophthalmol Vis Sci. 2021;6(2):115-121. doi: 10.11648/j.ijovs.20210602.19

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  • @article{10.11648/j.ijovs.20210602.19,
      author = {Olesia Zavoloka and Pavlo Bezditko},
      title = {Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences},
      journal = {International Journal of Ophthalmology & Visual Science},
      volume = {6},
      number = {2},
      pages = {115-121},
      doi = {10.11648/j.ijovs.20210602.19},
      url = {https://doi.org/10.11648/j.ijovs.20210602.19},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijovs.20210602.19},
      abstract = {The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.},
     year = {2021}
    }
    

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    T1  - Bacterial Keratitis in Type 1 Diabetic Patients: Course and Consequences
    AU  - Olesia Zavoloka
    AU  - Pavlo Bezditko
    Y1  - 2021/06/15
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    DO  - 10.11648/j.ijovs.20210602.19
    T2  - International Journal of Ophthalmology & Visual Science
    JF  - International Journal of Ophthalmology & Visual Science
    JO  - International Journal of Ophthalmology & Visual Science
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijovs.20210602.19
    AB  - The purpose was to define the peculiarities of the course and consequences of bacterial keratitis in patients with type 1 diabetes mellitus (DM1) depending on the stage of its severity. Methods. 34 DM1 patients (34 eyes) with bacterial keratitis whose initial bacteriological examination revealed pathogen sensitivity to the antibiotic ofloxacin participated in this study. All patients were treated topically with ofloxacin, antiseptics, repairing agents, antioxidants, mydriatics, artificial tears and systemically with anti-inflammatory agents. Patients were divided into two groups according to the severity of bacterial keratitis at the first visit. Research methods were as follows: visual acuity, tonometry, slit-lamp biomicroscopy of anterior and posterior eye segments, fluorescein dye test, non-contact corneal esthesiometry, anterior eye OCT and bacteriological studies. Results. Compared to the stage I, DM1 patients with stage II severity bacterial keratitis showed higher degree of pericorneal injection, larger and deeper corneal ulcer defect, deeper corneal infiltration and edema, higher mean corneal sensitivity threshold at all time point of the study, p Conclusions. Course and consequences of bacterial keratitis in type 1 diabetes mellitus patients depend on the stage of severity of bacterial keratitis.
    VL  - 6
    IS  - 2
    ER  - 

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Author Information
  • Department of Ophthalmology, Kharkiv National Medical University, Kharkiv, Ukraine

  • Department of Ophthalmology, Kharkiv National Medical University, Kharkiv, Ukraine

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